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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2014-20-4-238-248</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>МЕТАБОЛИЧЕСКИЙ СИНДРОМ И КОГНИТИВНЫЕ ДИСФУНКЦИИ У ЛИЦ ПОЖИЛОГО ВОЗРАСТА: ЖЕНЩИНЫ — ГРУППА РИСКА</article-title><trans-title-group xml:lang="en"><trans-title>METABOLIC SYNDROME AND COGNITIVE DYSFUNCTIONS IN OLDER ADULTS: WOMEN ARE A RISK GROUP</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубинина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubinina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат психологических наук, доцент, доцент кафедры клинической психологии и психологической помощи ФГБОУ ВПО «Российский государственный педагогический университет им. А.И. Герцена» (РГПУ им. А.И. Герцена);</p><p>научный сотрудник ФГБУ «Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева» Минздрава России.</p><p>Контактная информация: ФГБОУ ВПО «Российский государственный педагогический университет им. А.И. Герцена», наб. р. Мойки, 48, Санкт-Петербург, Россия, 191186. E-mail: trifonovahelen@yandex.ru (Елена Александровна Дубинина).</p></bio><bio xml:lang="en"><p>Corresponding author: Russian Herzen State Pedagogical University, 48 Moyka emb., St Petersburg, Russia, 191186. E-mail: trifonovahelen@yandex.ru (Elena A. Dubinina, PhD of Psychological Science, an Associate Professor at the Department of Clinical Psychology and Psychological Assistance at the Russian Herzen State Pedagogical University).</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ротарь</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rotar</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, заведующая научно-исследовательской лабораторией (НИЛ) Эпидемиологии артериальной гипертензии научно-исследовательского отдела артериальной гипертензии (НИО АГ) ФМИЦ им. В.А. Алмазова</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Могучая</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moguchaia</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аспирант, научный сотрудник НИЛ Эпидемиологии артериальной гипертензии НИО АГ ФМИЦ им. В.А. Алмазова и РГПУ им. А.И. Герцена</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бояринова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boyarinova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аспирант, научный сотрудник НИЛ Эпидемиологии артериальной гипертензии НИО АГ ФМИЦ им. В.А. Алмазова и РГПУ им. А.И. Герцена</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колесова</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolesova</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аспирант, научный сотрудник НИЛ Эпидемиологии артериальной гипертензии НИО АГ ФМИЦ им. В.А. Алмазова и РГПУ им. А.И. Герцена</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селикова</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Selikova</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аспирант кафедры клинической психологии и психологической помощи РГПУ им. А.И. Герцена</p></bio><bio xml:lang="en"><p>Russian Herzen State Pedagogical University, St Petersburg</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алёхин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekhin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующий кафедрой клинической психологии и психологической помощи РГПУ им. А.И. Герцена</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заместитель директора по научной работе ФМИЦ им. В.А. Алмазова, руководитель НИО АГ ФМИЦ им. В.А. Алмазова</p></bio><email xlink:type="simple">trifonovahelen@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский государственный педагогический университет им. А.И. Герцена, Санкт-Петербург&#13;
&#13;
Федеральное государственное бюджетное учреждение «Санкт-Петербургского научно-исследовательского психоневрологического института им. В.М. Бехтерева», Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Herzen State Pedagogical University, St Petersburg&#13;
St Petersburg Psychoneurological Research Institute n.a. V.M. Bekhterev, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный медицинский исследовательский центр имени В.А. Алмазова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Almazov Medical Research Centre, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Аспирант, научный сотрудник НИЛ Эпидемиологии артериальной гипертензии НИО АГ ФМИЦ им. В.А. Алмазова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Almazov Medical Research Centre, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-4"><institution>Российский государственный педагогический университет &#13;
им. А.И. Герцена, Санкт-Петербург</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Российский государственный педагогический университет &#13;
им. А.И. Герцена, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Herzen State Pedagogical University, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2015</year></pub-date><volume>20</volume><issue>4</issue><fpage>238</fpage><lpage>248</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дубинина Е.А., Ротарь О.П., Могучая Е.В., Бояринова М.А., Колесова Е.П., Селикова А.Ю., Алёхин А.Н., Конради А.О., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Дубинина Е.А., Ротарь О.П., Могучая Е.В., Бояринова М.А., Колесова Е.П., Селикова А.Ю., Алёхин А.Н., Конради А.О.</copyright-holder><copyright-holder xml:lang="en">Dubinina E.A., Rotar O.P., Moguchaia E.V., Boyarinova M.A., Kolesova E.P., Selikova A.Y., Alekhin A.N., Konradi A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/10">https://htn.almazovcentre.ru/jour/article/view/10</self-uri><abstract><p>Цель исследования — определение соотношений между метаболическим синдромом (МС) и его компонентами и когнитивными дисфункциями у лиц пожилого возраста.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Было обследовано 196 лиц (53 мужчины и 143 женщины) в возрасте от 64 до 86 лет, переживших блокаду Ленинграда и не имеющих в анамнезе острых нарушений мозгового кровообращения. При диагностике МС использовались критерии IDF и АНА/NHLBI (2009). Когнитивные функции оценивались с использованием шкалы Mini-Mental State Examination (MMSE).</p></sec><sec><title>Результаты</title><p>Результаты. У 48 % обследованных был диагностирован МС. Доминирующими компонентами являлись повышенное артериальное давление, центральное ожирение, гипергликемия. По результатам MMSE не было выявлено лиц с выраженными признаками деменции, но в 40 % случаев отмечались когнитивные нарушения разной степени. В структуре когнитивных дисфункций преобладали нарушения памяти и внимания. Итоговый показатель MMSE был связан с пониженными показателями оперативной слухоречевой памяти у женщин в возрастной подгруппе  70 лет (p &lt; 0,05). С когнитивными нарушениями были связаны отдельные компоненты МС, но только у женщин и преимущественно в возрастной подгруппе ≤70 лет. В этой группе при кардиометаболических отклонениях в наибольшей мере были снижены показатели по шкалам «Повтор фразы» и «Последовательность действий», при этом компонентом МС, наиболее тесно ассоциированным с когнитивными дисфункциями, являлась гипертриглицеридемия.</p></sec><sec><title>Выводы</title><p>Выводы. Женщины c МС (особенно при наличии гипертриглицеридемии) являются группой риска в отношении развития когнитивных дисфункций.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To determine relationship between metabolic syndrome (MS), its components and cognitive dysfunction among older adults.</p></sec><sec><title>Design and methods</title><p>Design and methods. Altogether 196 subjects who did not have a history of cerebrovascular events (53 males, 143 females aged 64–86) — survivors of Leningrad Siege — were examined. IDF и АНА/NHLBI (2009) criteria for MS were used. Cognitive function was assessed applying Mini-Mental State Examination scale (MMSE).</p></sec><sec><title>Results</title><p>Results. MS was identifi ed in 48 % subjects. The prevailing components were hypertension, central obesity, hyperglycemia. According to MMSE results there were no participants with signs of dementia, but in 40 % cognitive dysfunction of different degree was found. Memory and attention were most impaired. Total MMSE score was associated with decreased verbal auditory working memory in women of the age group ≤ 70 years old (p &lt; 0,05). Individual components of MS were associated with cognitive dysfunction, but only in women under or 70 years old. In this group participants with cardiometabolic disorders had the lowest scores at “Repetition” and “Sequence of actions” subscales. Hypertriglyceridemia was the component of MS most tightly associated with cognitive dysfunctions.</p></sec><sec><title> Conclusions</title><p> Conclusions. Women with MS (especially with hyper-triglyceridemia) are a risk group of cognitive dysfunctions.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>пожилой возраст</kwd><kwd>когнитивные дисфункции</kwd><kwd>гипертриглицеридемия</kwd><kwd>половые различия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>old age</kwd><kwd>cognitive dysfunctions</kwd><kwd>hypertriglyceridemia</kwd><kwd>sex differences</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Raffaitin C., Gin H., Empana J.P. et al. 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