arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2006-12-2-117-120arthyper-1053Research ArticleПРИГЛАШЕНИЕ К ДИСКУССИИDISCUSSIONИмеет ли значение артериальная гипертензия во время беременности в патогенезе метаболического синдрома у женщин?Does hypertension during pregnancy contribute to female metabolic syndrome?ТкачеваО. Н.TkachevaO. N.noemail@neicon.ruРазгуляеваН. Ф.RazgulaevaN. F.noemail@neicon.ruГусеваК. Ю.GusevaK. Y.noemail@neicon.ruСамсоненкоН. С.SamsonenkoN. S.noemail@neicon.ruМишинаИ. Е.MishinaI. E.noemail@neicon.ruБарабашкинаА. В.BarabashkinaA. V.noemail@neicon.ruМаксименкоЛ. П.MaksimenkoL. P.noemail@neicon.ruМокееваИ. П.MokeevaI. P.noemail@neicon.ruМГМСУRussian FederationГОУ ВПО ИвГМА РосздраваRussian FederationВладимирская областная клиническая больницаRussian FederationМУЗ «Городская клиническая больница №3 г. Иванова»Russian Federation200628042006122117120Copyright © Ткачева О.Н., Разгуляева Н.Ф., Гусева К.Ю., Самсоненко Н.С., Мишина И.Е., Барабашкина А.В., Максименко Л.П., Мокеева И.П., 20062006Ткачева О.Н., Разгуляева Н.Ф., Гусева К.Ю., Самсоненко Н.С., Мишина И.Е., Барабашкина А.В., Максименко Л.П., Мокеева И.П.Tkacheva O.N., Razgulaeva N.F., Guseva K.Y., Samsonenko N.S., Mishina I.E., Barabashkina A.V., Maksimenko L.P., Mokeeva I.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1053

Исследование предполагало в ходе проспективного наблюдения выявить особенности течения артериальной гипертензии и наличие метаболических нарушений у женщин, имевших различные варианты гипертензивных расстройств во время беременности. Через 10 лет после родов обследовано 38 женщин, которые имели во время беременности различные варианты АГ или высокое нормальное АД. В контрольную группу вошли 16 пациенток с нормотензивной беременностью. Выявлено, что наличие АГ во время беременности способствует не только стабилизации АД на высоких цифрах и поражению органов-мишеней, но и создает предпосылки к раннему формированию компонентов метаболического синдрома. Материнский вес до беременности и прибавка массы тела после родов, возможно, являются предикторами развития MC у женщин. Показано также, что применение препарата Энап в дозе 5-20 мг в сутки в течение 2-X месяцев позволяет не только достоверно снизить АД, но и улучшить показатели углеводного и липидного обмена у женщин с метаболическими нарушениями.

The aim of the study was to assess metabolic abnormalities in women with different patterns of hypertension during pregnancy in a prospective long-term observational study. 38 females were followed for 10 years after pregnancy. 16 females with normal pregnancy served as a control group. It is shown than hypertension during pregnancy predispose to blood pressure stabilization, target organ damage as well as metabolic disturbances and can predispose to metabolic syndrome manifestation. Maternal weight before pregnancy, and weight increase during pregnancy are predictors of future metabolic syndrome. It was shown also that enalapril 5-20 mg per day can significantly reduce blood pressure and improve metabolic glucose and lipid parameters in such women.

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The authors declare that there are no conflicts of interest present.