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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2014-20-4-249-253</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-11</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ БЕТА-АДРЕНОБЛОКАТОРОВ НА ЭТАПАХ СЕРДЕЧНО-СОСУДИСТОГО КОНТИНУУМА</article-title><trans-title-group xml:lang="en"><trans-title>BETA-BLOCKERS AT DIFFERENT STAGES OF CARDIOVASCULAR CONTINUUM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недошивин</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedoshivin</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, ученый секретарь ФГБУ «Федеральный медицинский исследовательский центр имени В.А. Алмазова» Минздрава России (ФМИЦ им. В.А. Алмазова)</p></bio><email xlink:type="simple">ms_olgavla@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, научный сотрудник научно-исследовательской лаборатории профилактической кардиологии ФМИЦ им. В.А. Алмазова </p><p>Контактная информация: ФГБУ «Федеральный медицинский центр им. В.А. Алмазова» Минздрава России, ул. Аккуратова, д. 2, Санкт-Петербург, Россия, 197341. E-mail: ms_olgavla@mail.ru (Орлова Ольга Владимировна).</p></bio><bio xml:lang="en"><p>Corresponding author: Federal Almazov Medical Research Centre, 2 Akkuratov st., St Petersburg, Russia, 197341. E-mail: ms_olgavla@mail.ru (Olga V. Orlova, PhD, Researcher at the Research Department of Preventive Cardiology).</p></bio><email xlink:type="simple">ms_olgavla@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральный медицинский исследовательский центр имени В.А. Алмазова, Санкт-Петербург<country>Россия</country></aff><aff xml:lang="en">Federal Almazov Medical Research Centre, St Petersburg<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2015</year></pub-date><volume>20</volume><issue>4</issue><fpage>249</fpage><lpage>253</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Недошивин А.О., Орлова О.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Недошивин А.О., Орлова О.В.</copyright-holder><copyright-holder xml:lang="en">Nedoshivin A.O., Orlova O.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/11">https://htn.almazovcentre.ru/jour/article/view/11</self-uri><abstract><p>В статье представлен обзор данных литературы и современных клинических рекомендаций по применению бета-адреноблокаторов в комплексной терапии сердечно-сосудистых заболеваний на различных этапах сердечно-сосудистого континуума</p></abstract><trans-abstract xml:lang="en"><p>A review of the current literature data and clinical recommendations on the use of beta-blockers in complex therapy of cardiovascular diseases at different stages of the cardiovascular continuum</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бета-адреноблокаторы</kwd><kwd>метопролол CR/XL</kwd><kwd>сердечно-сосудистый континуум</kwd></kwd-group><kwd-group xml:lang="en"><kwd>beta-blockers</kwd><kwd>metoprolol CR/XL</kwd><kwd>cardiovascular continuum</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ESH/ESC Guidelines for the management of arterial hypertension // Eur. 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