arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2007-13-1-69-75arthyper-1109Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESОценка спонтанного артериального барорефлекса методом совместного анализа показателей кратковременной изменчивости артериального давления и сердечного ритмаThe calculation of spontaneous arterial barorexlex sensitivity via joint analysis of arterial blood pressure and heart ratebeat-to-beat fluctuationБогачевМ. И.BogachevM. I.noemail@neicon.ruМамонтовО. В.MamontovO. V.noemail@neicon.ruКонрадиА. О.ConradyA. O.noemail@neicon.ruУльяницкийЮ. Д.UlyanitskiyY. D.noemail@neicon.ruФедеральный Центр сердца, крови и эндокринологии Росздрава им. В.А. АлмазоваРоссияAlmazov Federal Center of Heart, Blood and EndocrinologyRussian FederationСанкт-Петербургский государственный электротехнический университет «ЛЭТИ»РоссияSt. Petersburg Electrotechnocal universityRussian Federation2007280220071316975Copyright © Богачев М.И., Мамонтов О.В., Конради А.О., Ульяницкий Ю.Д., 20072007Богачев М.И., Мамонтов О.В., Конради А.О., Ульяницкий Ю.Д.Bogachev M.I., Mamontov O.V., Conrady A.O., Ulyanitskiy Y.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1109

Автономная дисфункция ассоциируется с негативным прогнозом у больных, как с патологией сердечно-сосудистой системы, так и при ряде других заболеваний. Чувствительность артериального барорефлекса является важным маркером, отражающим состояние автономной регуляции кровообращения. Настоящая работа посвящена новому подходу в оценке спонтанного артериального барорефлекса, позволяющему улучшить качество анализа данных, получаемых при неинвазивной непрерывной регистрации артериального давления и ритмограммы. Предложенный метод оценки совместной плотности вероятности артериального давления и R-R интервалов позволяет повысить эффективность использования фрагментов записи за счет включения в анализ большего числа отчетов, отличается лучшей воспроизводимостью и, вероятно, чувствительностью, по сравнению с традиционными методиками. Кроме того, предложенный метод позволяет оценить ряд дополнительных показателей, характеризующих артериальный барорефлекс. Все это существенно расширяет сферу использования характеристик спонтанного барорефлекса за счет возможности применения новой методики на более коротких записях, в том числе при ряде переходных состояний, упрощая расчеты и сокращая время записи гемодинамических параметров.

Autonomic dysfunction is associated with negative prognosis in cardiovascular patiens and several other pathologies. Arterial baroreflex sensitivity is an important marker of autonomic regulation. Present work is devoted to the new approach to spontaneous baroreflex estimation, which permit to improve quality of the continious blood pressure and ECG monitoring analysis. The method of combined estimation of probability density of blood pressure and R-R intervals is proposed in this article, which improves efficacy of use of date records due to the increased number of included beats in calculation. This method is appeared to have better reproducibility and, probably, sensitivity for autonomic dysfunction diagnosis compared to traditional approaches. Moreover, offered method allow to measure additional arterial barorexlex characteristics. Thus, the calculation of barorexlex sensitivity combined probability density allows to wide the sphere of spontaneous baroreflex estimation, including changeable conditions.

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The authors declare that there are no conflicts of interest present.