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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2008-14-4-320-323</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1249</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Гомоцистеинемия как фактор риска диабетической нефропатии у детей и подростков</article-title><trans-title-group xml:lang="en"><trans-title>Homocysteinemia as a risk factor of diabetic nephropathy in children and adolescents</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шуцкая</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shutskaya</surname><given-names>Zh. V.</given-names></name></name-alternatives><email xlink:type="simple">zhanna_shuckaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Городской Диабетологический Центр для детей и подростков ГУЗ ГП44<country>Россия</country></aff><aff xml:lang="en">Municipal Diabetes Center for Children and Adolescents, municipal clinics № 44<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2008</year></pub-date><volume>14</volume><issue>4</issue><fpage>320</fpage><lpage>323</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шуцкая Ж.В., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Шуцкая Ж.В.</copyright-holder><copyright-holder xml:lang="en">Shutskaya Z.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1249">https://htn.almazovcentre.ru/jour/article/view/1249</self-uri><abstract><p>В статье обобщены данные литературы о влиянии гомоцистеинемии на развитие патологических изменений сосудов у пациентов с различными нозологическими формами, включая сахарный диабет типов 1 и 2. Обсуждается вопрос о роли повышенного уровня гомоцистеина как независимого фактора риска диабетической нефропатии у детей и подростков. Рассматриваются вопросы фармакологической коррекции гомоцистеинемии</p></abstract><trans-abstract xml:lang="en"><p>This article summarizes data on homocysteinemia and its influence on vascular pathologic changes in patients with different diseases including diabetes type 1 and type 2. The role of homocystein as an independent risk factor for diabetic nephropathy in children and adolescents is discussed. The problem of homocysteinemia treatment is reviewed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>диабетическая нефропатия</kwd><kwd>дети</kwd><kwd>подростки</kwd><kwd>гомоцистеинемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Diabetic nephropathy</kwd><kwd>children</kwd><kwd>adolescents</kwd><kwd>homocysteinemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111-28.</mixed-citation><mixed-citation xml:lang="en">McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. 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