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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">arthyper-1304</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Возрастание резистентности к ритуксимабу в комбинации с полихимиотерапией при рецидивах индолентных лимфом. Обзор литературы и собственный опыт</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Ю. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вабищевич</surname><given-names>Р. И.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горюнова</surname><given-names>Е. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гиршова</surname><given-names>Л. Л.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Н. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зарицкий</surname><given-names>А. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГУЗ Городская больница № 31<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2008</year></pub-date><volume>14</volume><issue>1-S2</issue><fpage>108</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Ю.А., Вабищевич Р.И., Горюнова Е.Н., Гиршова Л.Л., Петров А.В., Медведева Н.В., Зарицкий А.Ю., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Алексеева Ю.А., Вабищевич Р.И., Горюнова Е.Н., Гиршова Л.Л., Петров А.В., Медведева Н.В., Зарицкий А.Ю.</copyright-holder><copyright-holder xml:lang="en">Алексеева Ю.А., Вабищевич Р.И., Горюнова Е.Н., Гиршова Л.Л., Петров А.В., Медведева Н.В., Зарицкий А.Ю.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1304">https://htn.almazovcentre.ru/jour/article/view/1304</self-uri><abstract><p>Пациенты с индолентными неходжкинскими лимфомами исходно чувствительны к комбинации химиотерапии и ритуксимаба. В рецидиве же ответ на лечение снижается до 50 %. В статье обсуждаются возможные механизмы резистентности к ритуксимабу.</p></abstract><kwd-group xml:lang="ru"><kwd>неходжкинская лимфома</kwd><kwd>резистентность к ритуксимабу</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Armitage J.O. and Weisenburger DD. (1998). J. Clin. Oncol. 16. 2780-2795.</mixed-citation><mixed-citation xml:lang="en">Armitage J.O. and Weisenburger DD. (1998). J. Clin. Oncol. 16. 2780-2795.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ghielmini M., Rufibach K., Salles G. et al. Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group of Clinical Cancer Research (SAKK). Ann Oncol. 2005: doi: 10.1093.</mixed-citation><mixed-citation xml:lang="en">Ghielmini M., Rufibach K., Salles G. et al. Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group of Clinical Cancer Research (SAKK). Ann Oncol. 2005: doi: 10.1093.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">McLaughlin P., Grillo-Lopez A.J., Link U.K., Levy R. Czuczman M.S. Williams M.E., Heyman M.R., Henee-Bruekler I., White C.A., Cahanillas L., Jain V.I., In A.D., Lister J., Wey K., Shen D. and Dallaire B.K. (1998). / Clin. Oncol., 8, 2825-2833.</mixed-citation><mixed-citation xml:lang="en">McLaughlin P., Grillo-Lopez A.J., Link U.K., Levy R. Czuczman M.S. Williams M.E., Heyman M.R., Henee-Bruekler I., White C.A., Cahanillas L., Jain V.I., In A.D., Lister J., Wey K., Shen D. and Dallaire B.K. (1998). / Clin. Oncol., 8, 2825-2833.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Witzig Т.Е., Flinn I.W., Gordon L.I. et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma. J Clin Oncol, 2002; 20: 3262-3269.</mixed-citation><mixed-citation xml:lang="en">Witzig Т.Е., Flinn I.W., Gordon L.I. et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma. J Clin Oncol, 2002; 20: 3262-3269.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Harjunpaa A., Wikiund T., Collan J., Janes R., Rosenberg J., Lee D., Gfillo-Lopez A. and Meri S. (2001). Leukemia Lymphoma, 42, 731-738.</mixed-citation><mixed-citation xml:lang="en">Harjunpaa A., Wikiund T., Collan J., Janes R., Rosenberg J., Lee D., Gfillo-Lopez A. and Meri S. (2001). Leukemia Lymphoma, 42, 731-738.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Osterborg A., Dyer M.J., Bunjes D., Pangalis G.A., Bastion Y., Catovsky D. and Mellstedt H. (1997). J. Clin. Oncol., 15, 1567-1574.</mixed-citation><mixed-citation xml:lang="en">Osterborg A., Dyer M.J., Bunjes D., Pangalis G.A., Bastion Y., Catovsky D. and Mellstedt H. (1997). J. Clin. Oncol., 15, 1567-1574.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jazirehi A.R., Bonavida B. Cellular and molecular signal transduction pathways modulated by rituximab (rituxan. anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention. Oncogene. 2005: 24: 2121-2143.</mixed-citation><mixed-citation xml:lang="en">Jazirehi A.R., Bonavida B. Cellular and molecular signal transduction pathways modulated by rituximab (rituxan. anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention. Oncogene. 2005: 24: 2121-2143.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Nieves Diaz M.D. Eugeny A., Osmanov M.D., Yulia A., Alexeeva M.D. Mikhail Yu., Byakhov M.D., Oleg N., Lipatov M.D., Sergey K., Kravchenko M.D., Ilya S., Zuzgin M.D., Felix T., Garzon M.D., Laurence Elias M.D. and Philippe Solal-Celigny M.D. Safety and Tdleiahiliiy of the Combination of Interleukin-2 (rIL-2) and Rituximab in Patients with Refractory Relapsed Follicular Non I lodgkin Lymphoma. Preliminary Data from the Pearl Study. Blond (ASH Annual Meeting Abstracts) 2005 106: Abstract 4783.</mixed-citation><mixed-citation xml:lang="en">Nieves Diaz M.D. Eugeny A., Osmanov M.D., Yulia A., Alexeeva M.D. Mikhail Yu., Byakhov M.D., Oleg N., Lipatov M.D., Sergey K., Kravchenko M.D., Ilya S., Zuzgin M.D., Felix T., Garzon M.D., Laurence Elias M.D. and Philippe Solal-Celigny M.D. Safety and Tdleiahiliiy of the Combination of Interleukin-2 (rIL-2) and Rituximab in Patients with Refractory Relapsed Follicular Non I lodgkin Lymphoma. Preliminary Data from the Pearl Study. Blond (ASH Annual Meeting Abstracts) 2005 106: Abstract 4783.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Jolay J., Zaffaroni L., Vaccari Т. еt al. Biologic response ot В lymphoma cells to anti-CD59 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis. Blood. 2000: 95: 3900-3908.</mixed-citation><mixed-citation xml:lang="en">Jolay J., Zaffaroni L., Vaccari Т. еt al. Biologic response ot В lymphoma cells to anti-CD59 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis. Blood. 2000: 95: 3900-3908.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
