arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2009-15-1-31-41arthyper-1314Research ArticleОБЗОРREVIEWОсобенности лечения сахарного диабета 2 типа у пациентов с коморбидной патологиейFeatures of treatment of type 2 diabetes mellitus in patients with concomitant pathologyШляхтоЕ. В.ShlyakhtoE. V.noemail@neicon.ruГриневаЕ. Н.GrinevaE. N.noemail@neicon.ruБабенкоА. Ю.BabenkoA. Yu.noemail@neicon.ruДроноваА. В.DronovaA. V.noemail@neicon.ruФГУ «Федеральный Центр сердца, крови и эндокринологии им. В.А. Алмазова»РоссияFederal Almazov Heart, Blood and Endocrinology CentreRussian Federation2009280220091513141Copyright © Шляхто Е.В., Гринева Е.Н., Бабенко А.Ю., Дронова А.В., 20092009Шляхто Е.В., Гринева Е.Н., Бабенко А.Ю., Дронова А.В.Shlyakhto E.V., Grineva E.N., Babenko A.Y., Dronova A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1314

У пациентов с сахарным диабетом типа 2 распространенность заболеваний сердечно-сосудистой системы крайне высока, а риск развития фатальных сердечно-сосудистых событий у них в 2-6 раз выше, чем у пациентов без сахарного диабета. У пациентов с сахарным диабетом типа 2 высока частота макрососудистых осложнений, таких как инсульт, атеросклероз периферических артерий, и сердечно-сосудистые осложнения являются основной причиной смерти у этой группы людей. В данном обзоре рассматриваются вопросы эффективности и безопасности различных сахароснижающих препаратов у пациентов с сахарным диабетом типа 2 и сопутствующей патологией. Обсуждается проблема лечения лиц пожилого возраста с сахарным диабетом типа 2 и сопутствующими заболеваниями, также в статье представлен предлагаемый алгоритм ведения таких пациентов.

Cardiovascular morbidity is widely spread in patients with type 2 diabetes mellitus. Cardiovascular mortality risk in patients with type 2 diabetes mellitus is twice to six times as high as in patients without diabetes. The incidence of macrovascular complications, such as strokes and peripheral arterial disease is very high, and the cardiovascular events associated with type 2 diabetes are the major cause of mortality in these patients. This article reviews the efficacy and safety of various antidiabetic drugs in patients with concomitant diseases, and regards diabetes management in elderly population. The available evidence on treatment of elder adults with type 2 diabetes and concomitant diseases is discussed, and a general approach to therapy is suggested.

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The authors declare that there are no conflicts of interest present.