arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2009-15-2-218-222arthyper-1345Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESРаспространенность сердечно-сосудистых заболеваний и сахарного диабета тип 2 у женщин перименопаузального возраста с синдромом поликистозных яичников в анамнезеPrevalence of cardiovascular diseases and type 2 diabetes mellitus in perimenopausal women with a history of the polycystic ovary syndromeПоповаП. В.PopovaP.pvpopova@yandex.ruБарановаЕ. В.BaranovaE. V.noemail@neicon.ruГриневаЕ. Н.GrinevaE. N.noemail@neicon.ruСанкт-Петербургский государственный медицинский университет им. академика И.П. ПавловаРоссияSt Petersburg Pavlov state UniversityRussian Federation200928042009152218222Copyright © Попова П.В., Баранова Е.В., Гринева Е.Н., 20092009Попова П.В., Баранова Е.В., Гринева Е.Н.Popova P., Baranova E.V., Grineva E.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1345

Целью работы явилось изучение распространенности сахарного диабета тип 2, артериальной гипертензии и ишемической болезни сердца (ИБС) у женщин перименопаузального возраста с синдромом поликистозных яичников (СПКЯ) в анамнезе. С помощью архивных данных было найдено 38 женщин в возрасте от 45 до 59 лет, наблюдавшихся в разных стационарах города по поводу СПКЯ в период с 1972 по 1989 г. Группу контроля составили 308 сопоставимых по возрасту женщин, проходивших профилактический осмотр. Исследуемая группа больных СПКЯ и группа сравнения не отличались по индексу массы тела, объёму талии и пропорции женщин с ожирением. В группе СПКЯ средний уровень гликемии натощак был достоверно выше, чем в группе контроля, чаще наблюдалась нарушенная гликемия натощак. При сравнении уровня общего холестерина и показателей липидного спектра достоверной разницы между группами выявлено не было. Частота сахарного диабета тип 2 и артериальной гипертензии оказалась достоверно выше в группе больных СПКЯ. По частоте встречаемости ИБС различий не оказалось.

The aim of our study was to evaluate the prevalence of type 2 diabetes mellitus (DM), arterial hypertension and coronary artery disease (CAD) in perimenopausal women with a history of polycystic ovary syndrome (PCOS) treatment. A group of 38 women aged 45-59 years, who had been treated for typical symptoms of PCOS in different hospitals of St Petersburg in 1972-1989 years, were included in the study. An age-matched sample of women without PCOS (N = 308) was selected. There was no difference in waist circumference, body mass index and in the proportions of women with obesity between these two groups. The mean fasting glucose was significantly higher and the impaired fasting glucose was found more often in PCOS women, than in controls. The mean concentrations of lipids showed no difference in the groups. Patients with PCOS had significantly higher prevalence of type 2 DM and arterial hypertension. There was no difference in the prevalence of CAD.

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The authors declare that there are no conflicts of interest present.