arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2009-15-3-309-313arthyper-1361Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESУровень адипонектина, показатели липидного и углеводного обменов у паци-ентов с абдоминальным ожирениемAdiponectin levels, lipid profile and glucose metabolism in patients with abdomi-nal obesityБеляеваО. Д.BelyaevaO.olga_bel@pisem.netБаженоваЕ. А.BazhenovaE. A.noemail@neicon.ruБерезинаА. В.BerezinaA. V.noemail@neicon.ruБольшаковаО. О.Bolsha-KovaO. O.noemail@neicon.ruЧубенкоЕ. А.ChubenkoE. A.noemail@neicon.ruГаранинаА. Е.GaraninaA. E.noemail@neicon.ruБарановаЕ. И.BaranovaE. I.noemail@neicon.ruБерковичО. А.BerkovichO. A.noemail@neicon.ruШляхтоЕ. В.ShlyakhtoE. V.noemail@neicon.ruГОУ ВПО «Санкт-Петербургский государственный медицинский университет им .акад. И.П. Павлова ФАЗСР»РоссияSt Petersburg Pavlov State Medical UniversityRussian FederationГОУ ВПО «Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова ФАЗСР», Институт сердечно-сосудистых заболеванийРоссияSt Petersburg Pavlov State Medical UniversityRussian Federation200928062009153309313Copyright © Беляева О.Д., Баженова Е.А., Березина А.В., Большакова О.О., Чубенко Е.А., Гаранина А.Е., Баранова Е.И., Беркович О.А., Шляхто Е.В., 20092009Беляева О.Д., Баженова Е.А., Березина А.В., Большакова О.О., Чубенко Е.А., Гаранина А.Е., Баранова Е.И., Беркович О.А., Шляхто Е.В.Belyaeva O., Bazhenova E.A., Berezina A.V., Bolsha-Kova O.O., Chubenko E.A., Garanina A.E., Baranova E.I., Berkovich O.A., Shlyakhto E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1361

В работе оценивали уровни адипонектина, показатели липидного и углеводного обменов у больных абдоминальным ожирением. Уровень адипонектина снижался по мере увеличения индекса массы тела. Установлены связи между уровнями адипонектина, триглицеридов и холестерина липопротеинов высокой плотности у больных абдоминальным ожирением. У больных артериальной гипертензией и абдоминальным ожирением значения общего холестерина, холестерина липопротеинов низкой плотности и триглицеридов были достоверно выше, чем у больных абдоминальным ожирением без артериальной гипертензии. С увеличением индекса массы тела возрастали уровень инсулина и индекс инсулинорезистентности (HOMA-IR). Установлены связи между индексом инсулинорезистентности и окружностью талии, индексом массы тела, уровнем адипонектина.

Adiponectin levels, lipid profile and parameters of glucose metabolism were evaluated in patients with abdominal obesity. It was found that adiponectin level negatively correlated with body mass index (BMI). The significant correlations were found between levels of adiponectin, triglycerides, and high-density lipoprotein (HDL) cholesterol in patients with abdominal obesity. Patients with abdominal obesity and arterial hypertension had higher levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides comparing to non-hypertensive patients with abdominal obesity. BMI increase positively correlated with insulin level and insulin resistance index estimated by homeostasis model assessment (HOMA-IR). Positive correlations were also determined between HOMA-IR and waist circumference, BMI, and adiponectin level.

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The authors declare that there are no conflicts of interest present.