arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2009-15-6-648-651arthyper-1447Research ArticleОБЗОРREVIEWОсобенности течения кардиомиопатий, обусловленных мутациями гена тропонина IClinical features of cardiomiopathies caused by cardiac troponin I mutations (review)ЮщенкоМ. В.YouschenkoM. V.ten_puppies@mail.ruШляхтоЕ. В.ShlyakhtoE. V.noemail@neicon.ruНовикГ. А.NovikG. A.noemail@neicon.ruКостареваА. А.KostarevaA. A.noemail@neicon.ruГудковаА. Я.GudkovaA. Ya.noemail@neicon.ruГОУ ВПО «Санкт-Петербургская государственная педиатрическая медицинская академия Федерального агенства по здравоохранению и социальному развитию»РоссияSt Petersburg State Pediatric Medical AcademyRussian FederationФГУ «Федеральный Центр сердца, крови и эндокринологии имени академика В.А. Алмазова Росмедтехнологий»РоссияAlmazov Federal Heart, Blood and Endocrinology CentreRussian FederationГОУ ВПО «Санкт Петербургский государственный медицинский университет имени академика И.П. Павлова Федерального агенства по здравоохранению и социальному развитию»РоссияPavlov State Medical UniversityRussian Federation200928122009156648651Copyright © Ющенко М.В., Шляхто Е.В., Новик Г.А., Костарева А.А., Гудкова А.Я., 20092009Ющенко М.В., Шляхто Е.В., Новик Г.А., Костарева А.А., Гудкова А.Я.Youschenko M.V., Shlyakhto E.V., Novik G.A., Kostareva A.A., Gudkova A.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1447

Представлен обзор литературы, посвященный клиническим и генетическим аспектам кардиомиопатий, обусловленных мутациями гена сердечного тропонина I. Отражены значительная клиническая гетерогенность заболевания с развитием как гипертрофического, так и рестриктивного фенотипов и высокий риск внезапной смерти.

Clinical and genetic aspects of cardiomyopathies caused by cardiac troponin I mutations are observed. Apparent clinical heterogeneity with development of both hypertrophic and restrictive phenotypes and high risk of sudden death are presented.

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The authors declare that there are no conflicts of interest present.