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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2010--2-</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1528</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Жесткость сосудистой стенки среди лиц с факторами риска сердечно-сосудистых заболеваний</article-title><trans-title-group xml:lang="en"><trans-title>Vascularstiffness in healthy subjects with cardiovascularrisk factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ротарь</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rotar</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">ahleague@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иваненко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanenko</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фурсова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fursova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солнцев</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Solntsev</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>O. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киталаева</surname><given-names>К. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kitalaeva</surname><given-names>K. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростовцева</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korostovtseva</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубровская</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubrovskaya</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзюбенко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzyubenko</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сокальская</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokalskaya</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шляхто</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Schlyakhto</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ «Федеральный Центр сердца, крови и эндокринологии им. В.А. Алмазова&#13;
Росмедтехнологий»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2010</year></pub-date><volume>16</volume><issue>2</issue><fpage>144</fpage><lpage>149</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ротарь О.П., Иваненко В.В., Фурсова И.В., Солнцев В.Н., Яковлева О.И., Киталаева К.Т., Коростовцева Л.С., Дубровская О.Б., Дзюбенко Н.А., Сокальская Е.А., Конради А.О., Шляхто Е.В., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Ротарь О.П., Иваненко В.В., Фурсова И.В., Солнцев В.Н., Яковлева О.И., Киталаева К.Т., Коростовцева Л.С., Дубровская О.Б., Дзюбенко Н.А., Сокальская Е.А., Конради А.О., Шляхто Е.В.</copyright-holder><copyright-holder xml:lang="en">Rotar O.P., Ivanenko V.V., Fursova I.V., Solntsev V.N., Yakovleva O.I., Kitalaeva K.T., Korostovtseva L.S., Dubrovskaya O.B., Dzyubenko N.A., Sokalskaya E.A., Konradi A.O., Schlyakhto E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1528">https://htn.almazovcentre.ru/jour/article/view/1528</self-uri><abstract><p>Целью настоящего исследования явилась оценка жесткости сосудистой стенки у относительно здоровых лиц, имеющих один фактор риска (компонент метаболического синдрома) или более, и ее взаимосвязь с выраженностью других оранных поражений и другими факторами риска. Материалы и методы. Обследовано 117 человек, имеющих по крайней мере один компонент метаболического синдрома. Гипертрофия левого желудочка выявлена у 45 %, микроальбуминурия - у 27 %, снижение лодыжечно-плечевого индекса - у 25 %, бессимптомный атеросклероз сонных артерий - у 25 % обследованных. Результаты. Ни один человек из обследованных не имел повышения скорости распространения пульсовой волны. Последняя коррелировала только с возрастом и уровнем артериального давления, а также с другими органными поражениями, но не была связана с метаболическим синдромом.</p></abstract><trans-abstract xml:lang="en"><p>Objective. The aim of the study was to assess vascular stiffness in healthy subjects with different cardiovascular risk factors (components of metabolic syndrome) and its relation to other target organ damage. Design and methods. We examined 117 patients having at least one metabolic syndrome component. Left ventricular hypertrophy according to ASE 2006 was detected in 45 %, microalbuminuria - in 27 %, decreased ankle-brachial index - in 24 %, carotid plaques in - 15 %. Results. None of the subjects had pulse wave velocity (PWV, carotid-femoral) more than 12 m/s. PWV was related only to age and blood pressure and correlated with other target organ damage level.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>жесткость сосудистой стенки</kwd><kwd>метаболический синдром</kwd><kwd>гипертрофия левого желудочка</kwd><kwd>лодыжечно-плечевой индекс</kwd><kwd>поражение органов мишеней</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vascular stiffness</kwd><kwd>metabolic syndrome</kwd><kwd>left ventricular hypertrophy</kwd><kwd>ankle-brachial index</kwd><kwd>target organ damage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines for the Management of Arterial Hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // J. 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