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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2014-20-6-538-545</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-159</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ СУТОЧНОГО ПРОФИЛЯ АРТЕРИАЛЬНОГО ДАВЛЕНИЯ У БОЛЬНЫХ ХРОНИЧЕСКИМ КАРДИОРЕНАЛЬНЫМ СИНДРОМОМ</article-title><trans-title-group xml:lang="en"><trans-title>CIRCADIAN BLOOD PRESSURE PROFILE IN PATIENTS WITH CHRONIC CARDIORENAL SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Serov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор кафедры терапии и профессиональных болезней медицинского факультета Ульяновского государственного университета.</p><p>Контактная информация: Серов Валерий Анатольевич, Ульяновский государственный университет, ул. Льва Толстого, 42, Ульяновск, Россия, 432027.Тел.: + 7 (8422)55–27–08. E-mail: Valery_serov@mail.ru</p></bio><bio xml:lang="en"><p>Corresponding author: Valeriy A. Serov, MD, PhD, Professor, Ulyanovsk State University, L. Tolstoy street, Ulyanovsk, 432027 Russia. Phone: + 7 (8422)55–27–08. E-mail: Valery_serov@mail.ru </p></bio><email xlink:type="simple">Valery_serov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шутов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shutov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующий кафедрой терапии и профессиональных болезней медицинского факультета Ульяновского государственного университета </p><p> </p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor, Head, Department of Internal and Professional Diseases, Medical Faculty</p></bio><email xlink:type="simple">Valery_serov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серова</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Serova</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, PhD student, Department of Internal and Professional Diseases, Medical Faculty</p></bio><email xlink:type="simple">Valery_serov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Head, Cardiology Department</p></bio><email xlink:type="simple">Valery_serov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмелькова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmelkova</surname><given-names>E. U.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Deputy Chief Physician</p></bio><email xlink:type="simple">Valery_serov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Ульяновский государственный университет, Ульяновск<country>Россия</country></aff><aff xml:lang="en">Ulyanovsk State University, Ulyanovsk<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Центральная городская клиническая больница г.Ульяновска, Ульяновск<country>Россия</country></aff><aff xml:lang="en">Ulyanovsk Central City Hospital, Ulyanovsk<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>06</day><month>03</month><year>2015</year></pub-date><volume>20</volume><issue>6</issue><fpage>538</fpage><lpage>545</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Серов В.А., Шутов А.М., Серова Д.В., Шевченко С.В., Шмелькова Е.Ю., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Серов В.А., Шутов А.М., Серова Д.В., Шевченко С.В., Шмелькова Е.Ю.</copyright-holder><copyright-holder xml:lang="en">Serov V.A., Shutov A.M., Serova D.V., Shevchenko S.V., Shmelkova E.U.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/159">https://htn.almazovcentre.ru/jour/article/view/159</self-uri><abstract><p>Цель исследования — изучение особенностей суточного профиля артериального давления (АД)</p><p>у больных хронической сердечной недостаточностью (ХСН) в зависимости от функционального состояния почек.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Обследовано 211 больных ХСН (126 мужчин и 85 женщин), из них 125 (59,2 %) пациентов с кардиоренальным синдромом и 86 (40,8 %) больных без хронической болезни почек (ХБП). Средний возраст составил 58,1 ± 10,8 года. ХБП диагностирована согласно Рекомендациям Национального общества нефрологов России 2012 года.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлено увеличение индексов времени и площади артериальной гипотонии у больных ХСН, ассоциированной с ХБП 3Б стадии и уменьшение степени ночного снижения как систолического, так и диастолического АД по мере нарастания тяжести ХБП.</p></sec><sec><title>Выводы</title><p>Выводы. 1. Для больных хроническим кардиоренальным синдромом характерно уменьшение степени ночного снижения АД при увеличении индексов времени и площади артериальной гипотонии в дневные часы. 2. Суточное мониторирование АД позволяет получить дополнительную информацию о состоянии гемодинамики у больных ХСН и может быть рекомендовано для включения в обследование данной категории больных.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To determine the features of circadian blood pressure (BP) profile depending on renal function in patients with chronic heart failure (CHF).</p></sec><sec><title>Design and methods</title><p>Design and methods. We examined 211 patients with CHF (126 men and 85 women), including 125 (59,2 %) patients with cardiorenal syndrome and 86 (40,8 %) patients without chronic kidney disease (CKD). Mean age was 58,1 ± 10,8 years. CKD was diagnosed according to the Scientific Society of Russian Nephrologists guidelines 2012.</p></sec><sec><title>Results</title><p>Results. An increase in time and area indices of arterial hypotension in patients with CHF, associated with CKD 3B stage was detected. Also, the nocturnal BP fall reduction was associated with increasing severity of CKD.</p></sec><sec><title>Conclusions</title><p>Conclusions. 1. The increase in nocturnal BP fall is associated with increasing in daytime area and time indices of arterial hypotension in patients with cardiorenal syndrome. 2. Twenty-four-hour ambulatory BP monitoring allows to obtain additional information on hemodynamic parameters in patients with CHF and should be recommended for this group of patients.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>хроническая болезнь почек</kwd><kwd>суточное мониторирование артериального давления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>chronic kidney disease</kwd><kwd>twenty-four-hour ambulatory blood pressure monitoring</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнов А. В., Добронравов В. А., Каюков И. Г. Проблема хронической болезни почек в современной медицине. Артериальная гипертензия. 2006; 12(3):185–193. [Smirnov AV, Dobronravov VA, Kayukov IG. Chronic kidney disease nowadays. 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