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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2011--2-</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1604</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Лечение артериальной гипертензии в XXI веке. Вопрос выбора монотерапии заменен на выбор рациональной комбинированной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Antihypertensive treatment in XXI century. Monotherapy or reasonable combination therapy?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Большакова</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Bolshakova</surname><given-names>O. O.</given-names></name></name-alternatives><email xlink:type="simple">oobolshakova@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ «Федеральный Центр сердца, крови и эндокринологии имени В.А. Алмазова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2011</year></pub-date><volume>17</volume><issue>2</issue><fpage>150</fpage><lpage>155</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Большакова О.О., Конради А.О., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Большакова О.О., Конради А.О.</copyright-holder><copyright-holder xml:lang="en">Bolshakova O.O., Konradi A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1604">https://htn.almazovcentre.ru/jour/article/view/1604</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>монотерапия</kwd><kwd>комбинирвоанная терапия</kwd><kwd>блокаторы ренин-ангиотензин-альдостероновой системы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>monotherapy</kwd><kwd>combination therapy</kwd><kwd>renin-angiotensin-aldosterone blockers</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lewington S., Clarke R., Qizilbash N., Peto R., Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies // Lancet. - 2002. - Vol. 360, № 9349. - P. 1903-1913.</mixed-citation><mixed-citation xml:lang="en">Lewington S., Clarke R., Qizilbash N., Peto R., Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies // Lancet. - 2002. - Vol. 360, № 9349. - P. 1903-1913.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mengen T., Uen S., Bramlage P. Management of hypertension with fixed dose combinations of candesartan cilexetil and hydrochlorothiazide: patient perspectives and clinical utility // Vasc. Health Risk Manag. - 2009. - Vol. 5. - P. 1043-1058. 3.</mixed-citation><mixed-citation xml:lang="en">Mengen T., Uen S., Bramlage P. Management of hypertension with fixed dose combinations of candesartan cilexetil and hydrochlorothiazide: patient perspectives and clinical utility // Vasc. Health Risk Manag. - 2009. - Vol. 5. - P. 1043-1058. 3.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Всероссийское научное общество кардиологов. Национальные клинические рекомендации. - М., 2009. - С. 7-34.</mixed-citation><mixed-citation xml:lang="en">Всероссийское научное общество кардиологов. Национальные клинические рекомендации. - М., 2009. - С. 7-34.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Mancia G., De Backer G &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22De%20Backer%20G%22%5BAuthor%5D&gt;., Dominiczak A &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22Dominiczak%20A%22%5BAuthor%5D&gt;. et al. Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // Eur. Heart J. - 2007. - Vol. 28, № 12. - P. 1462-1536.</mixed-citation><mixed-citation xml:lang="en">Mancia G., De Backer G &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22De%20Backer%20G%22%5BAuthor%5D&gt;., Dominiczak A &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22Dominiczak%20A%22%5BAuthor%5D&gt;. et al. Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // Eur. Heart J. - 2007. - Vol. 28, № 12. - P. 1462-1536.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mancia G., Laurent S., Agabiti-Rosei E. et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document // J. Hypertens. - 2009. - Vol. 27, № 11. - P. 212-215.</mixed-citation><mixed-citation xml:lang="en">Mancia G., Laurent S., Agabiti-Rosei E. et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document // J. Hypertens. - 2009. - Vol. 27, № 11. - P. 212-215.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Wolf-Maier K., Cooper R.S., Kramer H. et al. Hypertension treatment and control in five European countries, Canada, and the United States // Hypertension. - 2004. - Vol. 43, № 1. - P. 10-17.</mixed-citation><mixed-citation xml:lang="en">Wolf-Maier K., Cooper R.S., Kramer H. et al. Hypertension treatment and control in five European countries, Canada, and the United States // Hypertension. - 2004. - Vol. 43, № 1. - P. 10-17.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kearney P.M., Whelton M., Reynolds K., Muntner P., Whelton P.K., He J. Global burden of hypertension: analysis of worldwide data // Lancet. - 2005. - Vol. 365, № 9455. - P. 217-223.</mixed-citation><mixed-citation xml:lang="en">Kearney P.M., Whelton M., Reynolds K., Muntner P., Whelton P.K., He J. Global burden of hypertension: analysis of worldwide data // Lancet. - 2005. - Vol. 365, № 9455. - P. 217-223.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gaddam K.K., Oparil S. Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients? // Curr. Opin. Nephrol. Hypertens. - 2008. - Vol. 17, № 5. - P. 484-490.</mixed-citation><mixed-citation xml:lang="en">Gaddam K.K., Oparil S. Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients? // Curr. Opin. Nephrol. Hypertens. - 2008. - Vol. 17, № 5. - P. 484-490.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Pimento E., Oparil S. Role of aliskeren in cario-renal protection and use in hypertensives with multiple risk factors // Vasc. Health Risk Manag. - 2009. - Vol. 5. - P. 453-463. 10.</mixed-citation><mixed-citation xml:lang="en">Pimento E., Oparil S. Role of aliskeren in cario-renal protection and use in hypertensives with multiple risk factors // Vasc. Health Risk Manag. - 2009. - Vol. 5. - P. 453-463. 10.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">PROGESS Collaborative Study Group. Randomised trial period of perindopril-based blood pressure-lowering regimen among 6108 individuals with previous stroke or transient ischemic attack // Lancet. - 2001. - Vol. 358, № 9287. - P. 1033-1041.</mixed-citation><mixed-citation xml:lang="en">PROGESS Collaborative Study Group. Randomised trial period of perindopril-based blood pressure-lowering regimen among 6108 individuals with previous stroke or transient ischemic attack // Lancet. - 2001. - Vol. 358, № 9287. - P. 1033-1041.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Marre M., Puig J.G., Kokot F. et al. Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study // J. Hypertens. - 2004. - Vol. 22, № 8. - P. 1613-1622. 12.</mixed-citation><mixed-citation xml:lang="en">Marre M., Puig J.G., Kokot F. et al. Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study // J. Hypertens. - 2004. - Vol. 22, № 8. - P. 1613-1622. 12.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Dahlöf B., Gosse P., Guéret P. et al. Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study // J. Hypertens. - 2005. - Vol. 23, № 11. - P. 2063-2070. 13.</mixed-citation><mixed-citation xml:lang="en">Dahlöf B., Gosse P., Guéret P. et al. Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study // J. Hypertens. - 2005. - Vol. 23, № 11. - P. 2063-2070. 13.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">ADVANCE Collaborative Group. Rationale and design of the ADVANCE Study: a randomised trial of blood pressure lowering and intensive glucose control in high risk individuals with type 2 diabetes mellitus // J. Hypertens. - 2001. - Vol. 19, Suppl. 4. - P. S21-S28. 14.</mixed-citation><mixed-citation xml:lang="en">ADVANCE Collaborative Group. Rationale and design of the ADVANCE Study: a randomised trial of blood pressure lowering and intensive glucose control in high risk individuals with type 2 diabetes mellitus // J. Hypertens. - 2001. - Vol. 19, Suppl. 4. - P. S21-S28. 14.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">ADVANCE Collaborative Group. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial // Lancet. - 2007. - Vol. 370, № 9564. - P. 829-840.</mixed-citation><mixed-citation xml:lang="en">ADVANCE Collaborative Group. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial // Lancet. - 2007. - Vol. 370, № 9564. - P. 829-840.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Campbell N.R.C., Leiter L.A., Lachochelle P. et al. Hypertension in diabetes: a call to action // Can. J. Cardiol. - 2009. - Vol. 25, № 5. - P. 299-302.</mixed-citation><mixed-citation xml:lang="en">Campbell N.R.C., Leiter L.A., Lachochelle P. et al. Hypertension in diabetes: a call to action // Can. J. Cardiol. - 2009. - Vol. 25, № 5. - P. 299-302.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Leenen F.H., Dumais J., McInnis N.H. et al. Results of the Ontario survey on the prevalence and control of hypertension// Can. Med. Assoc. J. - 2008. - Vol. 178, № 11. - P. 1441-1449.</mixed-citation><mixed-citation xml:lang="en">Leenen F.H., Dumais J., McInnis N.H. et al. Results of the Ontario survey on the prevalence and control of hypertension// Can. Med. Assoc. J. - 2008. - Vol. 178, № 11. - P. 1441-1449.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Tuomilehto J., Rastenyte D., Birkenhager W.H. et al. Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. Systolic Hypertension in Europe Trial Investigators // N. Engl. J. Med. - 1999. - Vol. 340, № 9. - P. 677-684. 18.</mixed-citation><mixed-citation xml:lang="en">Tuomilehto J., Rastenyte D., Birkenhager W.H. et al. Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. Systolic Hypertension in Europe Trial Investigators // N. Engl. J. Med. - 1999. - Vol. 340, № 9. - P. 677-684. 18.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 // Br. Med. J. - 1998. - Vol. 317, № 7160. - P. 703-713.</mixed-citation><mixed-citation xml:lang="en">UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 // Br. Med. J. - 1998. - Vol. 317, № 7160. - P. 703-713.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Hansson L., Zanchetti A., Carson D.S. et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial // Lancet. - 1998. - Vol. 351, № 9142. - P. 1755-1761.</mixed-citation><mixed-citation xml:lang="en">Hansson L., Zanchetti A., Carson D.S. et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial // Lancet. - 1998. - Vol. 351, № 9142. - P. 1755-1761.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Mourad J., Waeber B., Zannad F. et al. on behalf of the investigators of the STRATHE trial. Comparison of different therapeutic strategies in hypertension: a low dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped care approach // J. Hypertens. - 2004. - Vol. 22, № 12. - P. 2386.</mixed-citation><mixed-citation xml:lang="en">Mourad J., Waeber B., Zannad F. et al. on behalf of the investigators of the STRATHE trial. Comparison of different therapeutic strategies in hypertension: a low dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped care approach // J. Hypertens. - 2004. - Vol. 22, № 12. - P. 2386.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Mogensen C.E., Viberti G., Halimi S. et al. Effect of a low-dose perindopril/indapamide on albuminuria in diabetes. Preterax in albuminuria regression: PREMIER // Hypertens. - 2003. - Vol. 41, № 5. - P. 1063-1071.</mixed-citation><mixed-citation xml:lang="en">Mogensen C.E., Viberti G., Halimi S. et al. Effect of a low-dose perindopril/indapamide on albuminuria in diabetes. Preterax in albuminuria regression: PREMIER // Hypertens. - 2003. - Vol. 41, № 5. - P. 1063-1071.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Asmar R.G., London G.M., O'Rourke M.F. Safar M.E. on behalf of the REASON Project Coordinators and investigators. Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patient: a comparison with atenolol &lt;http://www.ncbi.nlm.nih.gov/pubmed/11641310&gt; // Hypertension. - 2001. - Vol. 38. - P. 922-926.</mixed-citation><mixed-citation xml:lang="en">Asmar R.G., London G.M., O'Rourke M.F. Safar M.E. on behalf of the REASON Project Coordinators and investigators. Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patient: a comparison with atenolol &lt;http://www.ncbi.nlm.nih.gov/pubmed/11641310&gt; // Hypertension. - 2001. - Vol. 38. - P. 922-926.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Mourad J.J., Hanon O., Deverre J.R. et al. Improvement of impaired coronary vasodilator reserve in hypertensive patients by low-dose ACE inhibitor/diuretic therapy: a pilot PET study // J. Renin Angiotensin Aldosterone Syst. - 2003. - Vol. 4, № 2. - P. 94-95.</mixed-citation><mixed-citation xml:lang="en">Mourad J.J., Hanon O., Deverre J.R. et al. Improvement of impaired coronary vasodilator reserve in hypertensive patients by low-dose ACE inhibitor/diuretic therapy: a pilot PET study // J. Renin Angiotensin Aldosterone Syst. - 2003. - Vol. 4, № 2. - P. 94-95.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
