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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2011-17-3-264-268</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1625</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Электромеханические и гемодинамические нарушения, связанные с блокадой левой ножки пучка Гиса, у пациентов с артериальной гипертензией и ишемической болезнью сердца</article-title><trans-title-group xml:lang="en"><trans-title>Electromechanical and hemodynamical disturbances associated with left bundle branch block in hypertensive patients with coronary artery disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вождаева</surname><given-names>З. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vozhdaeva</surname><given-names>Z. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дупляков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Duplyakov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сысуенкова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sysuenkova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Землянова</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemlyanova</surname><given-names>M. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухова</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Gluckova</surname><given-names>V. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лотина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lotina</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хохлунов</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khokhlunov</surname><given-names>S. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУЗ СМКЦ ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Medical Center FMBA RF, Togliatti</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Самарский областной клинический кардиологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Regional Cardiology Clinic, Samara</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2011</year></pub-date><volume>17</volume><issue>3</issue><fpage>264</fpage><lpage>268</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вождаева З.И., Дупляков Д.В., Сысуенкова Е.В., Землянова М.Е., Глухова В.Л., Лотина А.С., Хохлунов С.М., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Вождаева З.И., Дупляков Д.В., Сысуенкова Е.В., Землянова М.Е., Глухова В.Л., Лотина А.С., Хохлунов С.М.</copyright-holder><copyright-holder xml:lang="en">Vozhdaeva Z.I., Duplyakov D.V., Sysuenkova E.V., Zemlyanova M.E., Gluckova V.L., Lotina A.S., Khokhlunov S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1625">https://htn.almazovcentre.ru/jour/article/view/1625</self-uri><abstract><p>изучить особенности электрической и механической диссинхронии на фоне полной блокады левой ножки пучка Гиса (ПБЛНПГ) у пациентов с артериальной гипертензией (АГ) и ишемической болезнью сердца (ИБС). Материалы и методы. Группу 1 составили 38 человек (16 мужчин/22 женщины, средний возраст составил 53,0 ± 9,7 года) без серьезных заболеваний сердечно-сосудистой системы. В группу 2 включили 24 пациентов (19 мужчин/5 женщин, средний возраст - 58,8 ± 8,9 года) с перенесенным инфарктом миокарда (ИМ) или перенесенной операцией коронарного шунтирования (КШ). Диссинхронию оценивали на трех уровнях: атриовентрикулярном (АВ), межжелудочковом (МЖ) и внутрижелудочковом (ВЖ). Результаты и заключение. Пациенты группы 1 имели меньшие объемные показатели (конечнодиастолический и конечносистолический объемы), лучшую сократительную способность, достоверных различий в состоянии диастолической функции левого желудочка, за исключением времени изоволюметрического расслабления (IVRT), отмечено не было. Параметры диссинхронии на АВ и ВЖ уровнях значимо не различались, однако на МЖ уровне пациенты с перенесенным инфарктом и операцией КШ имели достоверно более высокие значения (69,6 ± 18,9 против 59,7 ± 15,0 мс, р &lt; 0,03). Мы не получили значимой корреляции между продолжительностью комплекса QRS и проявлениями диссинхронии на различных уровнях ни в одной из групп. Между тем ряд параметров, отражающих гипертрофию левого желудочка, имел достоверную связь с параметрами диссинхронии.</p></abstract><trans-abstract xml:lang="en"><p>To assess electromechanical features of dyssynchrony associated with complete left bundle branch block in hypertensive patients with coronary artery disease. Design and methods. 1st group included 38 subjects (16 males and 22 females, mean age - 53,0 ± 9,7 years) without cardiovascular diseases. 2nd group consisted of 24 patients (19 males and 5 females, mean age - 58,8 ± 8,9 years) who survived through myocardial infarction or coronary bypass surgery in past. Dyssynchrony was assessed at atrioventricular (AV), interventricular (IV) and intraventricular (VV) levels. Results and conclusion. Subjects from the 1st group showed lower volume of left ventricle (end-diastolic and end-systolic volumes), better contractility, and parameters of diastolic function (besides isovolumic relaxation time) did not differ between the groups. Dyssynchrony was comparable at AV and IV levels, but patients with verified coronary artery disease ahd significantly higher VV dyssynchrony (69,6 ± 18,9 vs. 59,7 ± 15,0 msec, р &lt; 0,03). There was no correlation between QRS duration and dyssynchrony at any level. However, left ventricular hypertrophy correlated with dyssynchrony.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>блокада левой ножки пучка Гиса</kwd><kwd>диссинхрония левого желудочка</kwd><kwd>эхокардиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>coronary artery disease</kwd><kwd>left bundle branch block</kwd><kwd>dyssynchrony</kwd><kwd>echocardiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Диагностика и лечение хронической сердечной недостаточности. Национальные клинические рекомендации. Сб. / Под ред. Р.Г. Оганова. - 3-е издание. - М.: «Сицилия-Полиграф», 2010. - С. 70-163.</mixed-citation><mixed-citation xml:lang="en">Диагностика и лечение хронической сердечной недостаточности. Национальные клинические рекомендации. Сб. / Под ред. Р.Г. Оганова. - 3-е издание. - М.: «Сицилия-Полиграф», 2010. - С. 70-163.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vernooy K., Verbeek H., Peschar M. et al. Left bundle branch block induces ventricular remodeling and functional septal hypoperfusion // Eur. Heart J. - 2005. - Vol. 26, № 1. - P. 91-98.</mixed-citation><mixed-citation xml:lang="en">Vernooy K., Verbeek H., Peschar M. et al. Left bundle branch block induces ventricular remodeling and functional septal hypoperfusion // Eur. Heart J. - 2005. - Vol. 26, № 1. - P. 91-98.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Eriksson P., Hansson H.O., Eriksson H., Dellborg M. Bundle-brunch block in general male population: the study of men born 1913 // Circulation. - 1998. - Vol. 98, № 22. - P. 2494-2500.</mixed-citation><mixed-citation xml:lang="en">Eriksson P., Hansson H.O., Eriksson H., Dellborg M. Bundle-brunch block in general male population: the study of men born 1913 // Circulation. - 1998. - Vol. 98, № 22. - P. 2494-2500.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Tabuchi H., Kawain N., Sawayama T. Evaluation of left ventricular systolic function based on electrocardiogram with left bundle branch block // J. Cardiol. - 1998. - Vol. 31, № 1. - P. 23-30.</mixed-citation><mixed-citation xml:lang="en">Tabuchi H., Kawain N., Sawayama T. Evaluation of left ventricular systolic function based on electrocardiogram with left bundle branch block // J. Cardiol. - 1998. - Vol. 31, № 1. - P. 23-30.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Devereux R.B., Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method // Circulation. - 1977. - Vol. 55, № 4. - P. 613-618.</mixed-citation><mixed-citation xml:lang="en">Devereux R.B., Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method // Circulation. - 1977. - Vol. 55, № 4. - P. 613-618.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines for the management of arterial hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // Euro. Heart J. - 2007. - Vol. 28, № 12. - P. 1462-1536.</mixed-citation><mixed-citation xml:lang="en">Guidelines for the management of arterial hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // Euro. Heart J. - 2007. - Vol. 28, № 12. - P. 1462-1536.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Vidal B., Brugada J. Assessing mechanical cardiac asynchrony by echography. - [Электронный ресурс]. Available at: www.escardio.org.</mixed-citation><mixed-citation xml:lang="en">Vidal B., Brugada J. Assessing mechanical cardiac asynchrony by echography. - [Электронный ресурс]. Available at: www.escardio.org.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Кузнецов В.А. Сердечная ресинхронизирующая терапия: избранные вопросы. - М.: «Абис», 2007. - С. 37-68.</mixed-citation><mixed-citation xml:lang="en">Кузнецов В.А. Сердечная ресинхронизирующая терапия: избранные вопросы. - М.: «Абис», 2007. - С. 37-68.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Li Z.B., Dahlo F.B., Okin P.M. et al. Bundle branch block and cardiovascular morbidity and mortality in hypertensive patients with left ventricular hypertrophy: the losartan intervention for endpoint reduction in hypertension study // J. Hypertens. - 2008. - Vol. 26, № 4. - P. 1244-1249.</mixed-citation><mixed-citation xml:lang="en">Li Z.B., Dahlo F.B., Okin P.M. et al. Bundle branch block and cardiovascular morbidity and mortality in hypertensive patients with left ventricular hypertrophy: the losartan intervention for endpoint reduction in hypertension study // J. Hypertens. - 2008. - Vol. 26, № 4. - P. 1244-1249.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
