arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2011-17-4-293-304arthyper-1629Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESФибрилляция предсердий у больных артериальной гипертензиейAtrial fibrillation and arterial hypertensionБарановаЕ. И.BaranovaE. I.eibaranova@yahoo.comГОУ ВПО «Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова Росздрава»РоссияPavlov St Petersburg State Medical UniversityRussian Federation201128082011174293304Copyright © Баранова Е.И., 20112011Баранова Е.И.Baranova E.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1629

Обзор литературы посвящен фибрилляции предсердий у больных артериальной гипертензией. Рассмотрены патологические механизмы (гемодинамические, структурные и электрофизиологические) формирования фибрилляции предсердий при артериальной гипертензии и роль ренин-ангиотензин-альдостероновой системы в патогенезе аритмии. В нем освещены проблемы первичной и вторичной профилактики фибрилляции предсердий с помощью антигипертензивной терапии, в том числе при использовании ингибиторов ангиотензинпревращающего ферменты, блокаторов рецепторов ангиотензина II 1 типа и других антигипертензивных средств. В обзоре приведены современные представления о проведении профилактики тромбоэмболий у больных фибрилляцией предсердий с артериальной гипертензией.

Review deals with atrial fibrillation and arterial hypertension. Possible pathological mechanisms of atrial fibrillation due to hypertension include haemodynamic effects, structural and electrophysiological heart remodeling partly connected with activation of renin-angiotensin-aldosterone system. Problems of primary and secondary prevention of atrial fibrillation in hypertensive patients are discussed, particularly the role of antihypertensive treatment including angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers. Risk stratification for stroke and thromboembolism and anticoagulation therapy are discussed.

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The authors declare that there are no conflicts of interest present.