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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2011-17-4-372-378</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1640</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL TRIALS</subject></subj-group></article-categories><title-group><article-title>Снижение риска осложнений у больных артериальной гипертензией: преимущества комбинированной гипотензивной терапии периндоприлом и амлодипином
(по материалам Конгресса Европейского общества артериальной гипертонии 2011 года)</article-title><trans-title-group xml:lang="en"><trans-title>The decrease of complication rate in hypertensives: Benefits of combined antihypertensive treatment by Perindopril and Amlodipine
(adapted from the materials from the Annual Scientific Meeting of the European Society of Hypertension [ESH], 2011)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>Y. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шубина</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Shubina</surname><given-names>A. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ РК НПК Минздравсоцразвития РФ, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Russian Cardiology Research and Production Complex of the Ministry of Health and Social Development of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2011</year></pub-date><volume>17</volume><issue>4</issue><fpage>372</fpage><lpage>378</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Карпов Ю.А., Шубина А.Т., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Карпов Ю.А., Шубина А.Т.</copyright-holder><copyright-holder xml:lang="en">Karpov Y.A., Shubina A.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1640">https://htn.almazovcentre.ru/jour/article/view/1640</self-uri><abstract><p>Эффективный контроль уровня артериального давления (АД) остается ключевым фактором снижения сердечно-сосудистой заболеваемости и смертности. Основными критериями выбора рациональной гипотензивной терапии являются: оптимальный гипотензивный эффект и доказанное снижение риска сердечно-сосудистых осложнений и смертности. 18 июня 2011 года в рамках Европейского Конгресса по артериальной гипертензии (АГ) и сердечно-сосудистой профилактике состоялся симпозиум «Смертельна ли АГ сегодня?», на котором рассматривались вопросы эффективной гипотензивной терапии у больных АГ с помощью фиксированной комбинации периндоприла и амлодипина (препарат престанс). Препарат может быть рекомендован больным с неконтролируемой АГ, с высоким риском развития осложнений, сахарным диабетом или ишемической болезнью сердца.</p></abstract><trans-abstract xml:lang="en"><p>Effective blood pressure (BP) control remains a key factor in the reduction of cardiovascular morbidity and mortality. Main criteria of choice of rational antihypertensive therapy include optimal antihypertensive effect and documented reduction of the risk of cardiovascular events and mortality. On 18th June, 2011, at the European Meeting on Hypertension and Cardiovascular Prevention, the symposium «Is hypertension a fatal disease today?» was held with discussions on the effective antihypertensive therapy in hypertensive patients using fixed-dose combination of perindopril and amlodipine (Prestance). This treatment can be recommended as preferable for hypertensive patients with uncontrolled BP, with high risk of complications, with diabetes mellitus and coronary heart disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>сердечно-сосудистые осложнения</kwd><kwd>предикторы осложнений</kwd><kwd>целевое артериальное давление</kwd><kwd>фиксированные комбинации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>cardiovascular complications</kwd><kwd>predictors of complications</kwd><kwd>target blood pressure</kwd><kwd>fixed-dose combinations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lawes C.M &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22Lawes%20CM%22%5BAuthor%5D&gt;., Vander Hoorn S &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22Vander%20Hoorn%20S%22%5BAuthor%5D&gt;., Rodgers A &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22Rodgers%20A%22%5BAuthor%5D&gt;; International Society of Hypertension &lt;http://www.ncbi.nlm.nih.gov/pubmed?term=%22International%20Society%20of%20Hypertension%22%5BCorporate%20Author%5D&gt;. 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