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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2012-18-4-298-302</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1711</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Риск развития артериальной гипертензии и личностная тревожность в открытой популяции среди женщин 25-64 лет (16-летнее эпидемиологическое исследование — программа ВОЗ «MONICA-psychosocial»)</article-title><trans-title-group xml:lang="en"><trans-title>Risk of arterial hypertension and personal anxiety in 25—64 years old female population: A 16-year epidemiological study based on the WHO program «MONICA-psychosocial»</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеваний» СО РАМН; ФГБУ «Научно-исследовательский институт терапии» СО РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Collaborative Laboratory of Cardiovascular Diseases Epidemiology SB RAMS. Novosibirsk, Russia; Laboratory of Psychological and Sociological Issues of Internal Medicine, Institute of Internal Medicine SB RAMS. Novosibirsk, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2012</year></pub-date><volume>18</volume><issue>4</issue><fpage>298</fpage><lpage>302</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Панов Д.О., Громова Е.А., Гагулин И.В., Гафарова А.В., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Панов Д.О., Громова Е.А., Гагулин И.В., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Panov D.O., Gromova E.A., Gagulin I.V., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1711">https://htn.almazovcentre.ru/jour/article/view/1711</self-uri><abstract><p>Цель исследования — определение влияния личностной тревожности на относительный риск (ОР) развития артериальной гипертензии (АГ) в течение 16 лет в открытой популяции среди женщин 25-64 лет. Материалы и методы. В рамках программы ВОЗ «MONICA-psychosocial» в 1994 г. была обследована случайная репрезентативная выборка женщин (n = 870) в возрасте 25-64 лет, жителей одного из района Новосибирска. Личностная тревожность была изучена при помощи теста Спилбергера. В течение 16-летнего периода (1994-2010 гг.) в когорте исследовали все впервые возникшие случаи АГ. Для оценки ОР развития сердечно-сосудистых заболеваний (ССЗ) использовали регрессионную модель Кокса. Результаты. В течение первых 5 лет ОР развития АГ был в 2,38 раза (95 % ДИ = 1,137-4,993; p &lt; 0,05); в течение 10 лет — в 1,85 раза (95 % ДИ = 1,075-3,194; p &lt; 0,05); в течение 14 лет — в 1,46 раза (95 % ДИ = 0,992-2,040; p &lt; 0,05) выше у женщин с высоким уровнем личностной тревожности. Частота возникновения АГ была выше у замужних женщин, руководителей, работниц физического труда, лиц с низким уровнем образования с высоким уровнем личностной тревожности. Заключение. Максимальный риск развития АГ в открытой популяции среди женщин 25-64 лет с высоким уровнем личностной тревожности наблюдается в течение первых 5 лет, причем на развитие АГ влияет профессиональный уровень, семейный статус, образовательный уровень. </p></abstract><trans-abstract xml:lang="en"><p>Objective. To determine the effect of personal anxiety on the relative risk of arterial hypertension (AH) in female population 25-64 years during 16 years. Design and methods. Within the framework of the third screening of the WHO «MONICA-psychosocial» program random representative sample of women aged 25-64 years (n = 870), who were residents of one district in Novosibirsk, were surveyed. Personal anxiety was measured by Spilberger’s test. From 1995 to 2010 women were followed up for 16 years for the incidence of AH. Cox proportional regression model was used for the estimation of relative risk. Results. During the first 5 years the relative risk of AH development was 2,38 times higher (95 % CI = 1,137-4,993; p &lt; 0,05); for 10 years — 1,85 times higher (95 % CI = 1,075-3,194; p &lt; 0,05); for 16 years — 1,46 times higher (95 % CI = 0,992-2,040; p &lt; 0,05) in women with high levels of anxiety. The rate of AH incidence was higher in married women, managers, physical labour employees and in those with low level of education. Conclusion. Risk of AH incidence in population of women aged 25-64 years with high level of personal anxiety was the highest during the first 5 years of follow-up. Incidence of AH is affected by occupation and marital status, educational level. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпидемиология</kwd><kwd>личностная тревожность у женщин</kwd><kwd>артериальная гипертензия</kwd><kwd>относительный риск</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epidemiology</kwd><kwd>personal anxiety in women</kwd><kwd>arterial hypertension</kwd><kwd>relative risk</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alboni P., Alboni M. Psychosocial factors as predictors of atherosclerosis and cardiovascular events: contribution from animal models // G. Ital. Cardiol. (Rome). — 2006. — Vol. 7, № 11. — Р. 747-753.</mixed-citation><mixed-citation xml:lang="en">Alboni P., Alboni M. Psychosocial factors as predictors of atherosclerosis and cardiovascular events: contribution from animal models // G. Ital. Cardiol. (Rome). — 2006. — Vol. 7, № 11. — Р. 747-753.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Buchholz K., Schorr U., Turan S. et al. Emotional irritability and anxiety in salt-sensitive persons at risk for essential hypertension // Psych. Med. — 1999. — Vol. 8, № 49. — Р. 284-289.</mixed-citation><mixed-citation xml:lang="en">Buchholz K., Schorr U., Turan S. et al. Emotional irritability and anxiety in salt-sensitive persons at risk for essential hypertension // Psych. Med. — 1999. — Vol. 8, № 49. — Р. 284-289.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ibatov A. Anxiety and prognosis of patients with ischemic heart disease // EuroPRevent, 2009, Abstract book. — Р106. — 2009. — Р. 35.</mixed-citation><mixed-citation xml:lang="en">Ibatov A. Anxiety and prognosis of patients with ischemic heart disease // EuroPRevent, 2009, Abstract book. — Р106. — 2009. — Р. 35.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Saboya P.M., Zimmermann P.R., Bodanese L.C. Association between anxiety or depressive symptoms and arterial hypertension, and their impact on the quality of life // Int. J. Psychiatry Med. — 2010. — Vol. 40, № 3. — Р. 307-320.</mixed-citation><mixed-citation xml:lang="en">Saboya P.M., Zimmermann P.R., Bodanese L.C. Association between anxiety or depressive symptoms and arterial hypertension, and their impact on the quality of life // Int. J. Psychiatry Med. — 2010. — Vol. 40, № 3. — Р. 307-320.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">MONICA Psychosocial Optional Study. Suggested measurement instruments. — WHO Facsimile Urgent 3037 MRC, 1988. — Р. 33.</mixed-citation><mixed-citation xml:lang="en">MONICA Psychosocial Optional Study. Suggested measurement instruments. — WHO Facsimile Urgent 3037 MRC, 1988. — Р. 33.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Spielberger C.D. Anxiety as an emotional state / In: Anxiety: current trends in theory and research. — Vol. 1. — NY: Academic Press, 1972. — Р. 24-49.</mixed-citation><mixed-citation xml:lang="en">Spielberger C.D. Anxiety as an emotional state / In: Anxiety: current trends in theory and research. — Vol. 1. — NY: Academic Press, 1972. — Р. 24-49.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jonas B., Lando J. Negative affect as a prospective risk factor for hypertension // Psychosom. Med. — 2000. — Vol. 62, № 2. — P. 188-196.</mixed-citation><mixed-citation xml:lang="en">Jonas B., Lando J. Negative affect as a prospective risk factor for hypertension // Psychosom. Med. — 2000. — Vol. 62, № 2. — P. 188-196.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Markovitz J., Matthews K., Wing R. et al. Psychological, biological and health behavior predictors of blood pressure changes in middle-aged women // J. Hypertens. — 1991. — Vol. 9, № 5. — Р. 399-406.</mixed-citation><mixed-citation xml:lang="en">Markovitz J., Matthews K., Wing R. et al. Psychological, biological and health behavior predictors of blood pressure changes in middle-aged women // J. Hypertens. — 1991. — Vol. 9, № 5. — Р. 399-406.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Orth-Gomer K., Wamala S.P., Horsten M. et al. Marital stress worsens prognosis in women with coronary heart disease: The Stockholm Female Coronary Risk Study // J. Am. Med. Assoc. — 2001. — Vol. 285, № 10. — Р. 1289-1290.</mixed-citation><mixed-citation xml:lang="en">Orth-Gomer K., Wamala S.P., Horsten M. et al. Marital stress worsens prognosis in women with coronary heart disease: The Stockholm Female Coronary Risk Study // J. Am. Med. Assoc. — 2001. — Vol. 285, № 10. — Р. 1289-1290.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Balog P., Janszky I., Leineweber C. et al. Depressive symptoms in relation to marital and work stress in women with and without coronary heart disease. The Stockholm Female Coronary Risk Study // J. Psychosom. Res. — 2003. — Vol. 54, № 2. — Р. 113-119.</mixed-citation><mixed-citation xml:lang="en">Balog P., Janszky I., Leineweber C. et al. Depressive symptoms in relation to marital and work stress in women with and without coronary heart disease. The Stockholm Female Coronary Risk Study // J. Psychosom. Res. — 2003. — Vol. 54, № 2. — Р. 113-119.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brook J.S., Brook D.W., Zhang C. Psychosocial predictors of nicotine dependence in Black and Puerto Rican adults: a longitudinal study // Nicotine Tob. Res. — 2008. — Vol. 10, № 6. — Р. 959-967.</mixed-citation><mixed-citation xml:lang="en">Brook J.S., Brook D.W., Zhang C. Psychosocial predictors of nicotine dependence in Black and Puerto Rican adults: a longitudinal study // Nicotine Tob. Res. — 2008. — Vol. 10, № 6. — Р. 959-967.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Andersen I., Diderichsen F., Kornerup H. et al. Major life events and the risk of ischaemic heart disease: does accumulation increase the risk? // Int. J. Epidemiol. — 2011. — Vol. 40, № 4. — Р. 904-913.</mixed-citation><mixed-citation xml:lang="en">Andersen I., Diderichsen F., Kornerup H. et al. Major life events and the risk of ischaemic heart disease: does accumulation increase the risk? // Int. J. Epidemiol. — 2011. — Vol. 40, № 4. — Р. 904-913.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Petersen H., Boysen G., Prescott E. et al. Major life events and the risk of cardiovascular disease: findings from Copenhagen city heart study // EuroPRevent, 2008. Abstract book.</mixed-citation><mixed-citation xml:lang="en">Petersen H., Boysen G., Prescott E. et al. Major life events and the risk of cardiovascular disease: findings from Copenhagen city heart study // EuroPRevent, 2008. Abstract book.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kozakiewicz K., Wojakowski W, Michalewska-Wludarc-zyk A. Inverse correlation between socioeconomic status and risk of cardiovascular death // Eur. Heart J. — 2008. — Vol. 29, Abstr. Suppl. — P. 856.</mixed-citation><mixed-citation xml:lang="en">Kozakiewicz K., Wojakowski W, Michalewska-Wludarc-zyk A. Inverse correlation between socioeconomic status and risk of cardiovascular death // Eur. Heart J. — 2008. — Vol. 29, Abstr. Suppl. — P. 856.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Honjo K., Iso H. Education, social roles, and the risk of cardiovascular disease among middle-aged Japanese women // Stroke. — 2008. — Vol. 39, № 10. — P. 2886-2890.</mixed-citation><mixed-citation xml:lang="en">Honjo K., Iso H. Education, social roles, and the risk of cardiovascular disease among middle-aged Japanese women // Stroke. — 2008. — Vol. 39, № 10. — P. 2886-2890.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Rosengren A., Subramanian S.V., Islam S. Education and risk for acute myocardial infarction in 52 high, middle and low-income countries: INTERHEART case-control study // Heart. — 2009. — Vol. 95, № 24. — Р. 2014-2022.</mixed-citation><mixed-citation xml:lang="en">Rosengren A., Subramanian S.V., Islam S. Education and risk for acute myocardial infarction in 52 high, middle and low-income countries: INTERHEART case-control study // Heart. — 2009. — Vol. 95, № 24. — Р. 2014-2022.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Гафарова А.В., Гафаров В.В., Громова Е.А. и др. Личностная тревожность, как свойство личности, ее связь с другими психосоциальными факторами и ишемической болезнью сердца // Мир науки, культуры, образования. — 2009. — Т. 17, № 5. — С. 197-199.</mixed-citation><mixed-citation xml:lang="en">Гафарова А.В., Гафаров В.В., Громова Е.А. и др. Личностная тревожность, как свойство личности, ее связь с другими психосоциальными факторами и ишемической болезнью сердца // Мир науки, культуры, образования. — 2009. — Т. 17, № 5. — С. 197-199.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В. и др. Нарушения сна и риск в течение 14 лет возникновения артериальной гипертензии в популяции мужчин 25-64 лет (эпидемиологическое исследование на основе программы ВОЗ «MONICA-psychosocial») // Артериальная гипертензия. — 2009. — Т. 15, № 4. — С. 431-435</mixed-citation><mixed-citation xml:lang="en">Гафаров В.В., Громова Е.А., Гагулин И.В. и др. Нарушения сна и риск в течение 14 лет возникновения артериальной гипертензии в популяции мужчин 25-64 лет (эпидемиологическое исследование на основе программы ВОЗ «MONICA-psychosocial») // Артериальная гипертензия. — 2009. — Т. 15, № 4. — С. 431-435</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kivimaki M., Leino-Arjas P., Luukkonen R. Work stress and risk of cardiovascular mortality: prospective cohort study of industrial employees // Br. Med. J. — 2002. — Vol. 325, № 7377. — Р. 1386.</mixed-citation><mixed-citation xml:lang="en">Kivimaki M., Leino-Arjas P., Luukkonen R. Work stress and risk of cardiovascular mortality: prospective cohort study of industrial employees // Br. Med. J. — 2002. — Vol. 325, № 7377. — Р. 1386.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Gallo W.T., Teng H.M., Falba T.A., Kasl S.V., Krum-holz H.M., Bradley E.H. The impact of late career job loss on myocardial infarction and stroke: a 10-year follow up using the health and retirement survey // Occup. Environ. Med. — 2006. — Vol. 63, № 10. — Р. 683-687.</mixed-citation><mixed-citation xml:lang="en">Gallo W.T., Teng H.M., Falba T.A., Kasl S.V., Krum-holz H.M., Bradley E.H. The impact of late career job loss on myocardial infarction and stroke: a 10-year follow up using the health and retirement survey // Occup. Environ. Med. — 2006. — Vol. 63, № 10. — Р. 683-687.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
