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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2019-25-4-357-375</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1859</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры и лекции</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Артериальная гипертония у пациентов старших возрастных групп: когда и кому нужен гериатрический подход?</article-title><trans-title-group xml:lang="en"><trans-title>Arterial hypertension in older adults:  who needs geriatric approach?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котовская</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotovskaya</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котовская Юлия Викторовна — профессор, заместитель директора по научной работе1‑я ул. Леонова, д. 16, Москва,  129226</p></bio><bio xml:lang="en"><p>Yulia V. Kotovskaya, MD, PhD, Professor, Deputy Director on Research, Russian Clinical and Research Center of Gerontology, Pirogov Russian National Research Medical University</p><p>1st Leonova street, 16, Moscow,  129226</p></bio><email xlink:type="simple">kotovskaya_yv@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткачёва Ольга Николаевна — доктор медицинских наук, профессор, директор ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пи­рогова» Минздрава России, Российский геронтологический научно-клинический центрМосква</p></bio><bio xml:lang="en"><p>Olga N. Tkacheva, MD, PhD, DSc, Professor, Director, Pirogov Russian National Research Medical University of Ministry of Health of Russian federation “Russian Gerontology Research and Clinical Centre”Moscow</p></bio><email xlink:type="simple">tkacheva@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Обособленное структурное подразделение  «Российский геронтологический научно-клинический центр» Федерального государственного автономного  образовательного учреждения высшего образования  «Российский национальный исследовательский  медицинский университет имени Н. И. Пирогова»  Минздрава России</institution></aff><aff xml:lang="en"><institution>Russian Clinical and Research Center of Gerontology,  Pirogov National Research Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2019</year></pub-date><volume>25</volume><issue>4</issue><fpage>357</fpage><lpage>375</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Котовская Ю.В., Ткачева О.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Котовская Ю.В., Ткачева О.Н.</copyright-holder><copyright-holder xml:lang="en">Kotovskaya Y.V., Tkacheva O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1859">https://htn.almazovcentre.ru/jour/article/view/1859</self-uri><abstract><p>Повышенное артериальное давление (АД) является важным фактором риска не только сердечно-сосудистой заболеваемости и смертности, но и снижения когнитивных функций и утраты автономности в более позднем периоде жизни. Рандомизированные клинические исследования (РКИ) в популяциях пациентов старшего возраста, проживающих дома, с невысокой коморбидностью и сохранной автономностью указывают на пользу снижения повышенного АД у пациентов старше 80 лет. Пациенты старшего возраста со старческой астенией, с утратой автономности и рядом других гериатрических проблем систематически исключались из РКИ, а наблюдательные исследования у этих групп пациентов указывают на повышение заболеваемости и смертности при более низком уровне АД и на фоне антигипертензивной терапии.  Очевидно, что у очень пожилых пациентов не может применяться универсальная стратегия лечения АГ в виду значительной гетерогенности их функционального статуса. В обзоре обсуждается подход с позиции гериатрической медицины, который предполагает оценку функционального статуса пациента, наличия старческой астении и степени сохранности автономности для выбора тактики антигипертензивной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Elevated blood pressure (BP) is an important risk factor not only for cardiovascular morbidity and mortality, but also for cognitive decline and loss of autonomy in later life. Randomized clinical trials (RCTs) in populations of older patients living at home with low comorbidity and preserved autonomy showed benefits of decreasing the elevated BP in patients older than 80 years. Older patients with frailty, loss of autonomy and other geriatric problems were systematically excluded from the RCTs. Observational studies in these groups of patients showed an increase in morbidity and mortality at a lower level of BP during antihypertensive therapy. Obviously, in very elderly patients a universal strategy for the BP lowering cannot be applied due to the significant heterogeneity of their functional status. In this review geriatric approach based on assessment of the functional status of the elderly patient, the presence of frailty and degree of loss of autonomy as a basis for decision-making process regarding the antihypertensive therapy is discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>старение</kwd><kwd>старческая астения</kwd><kwd>артериальная гипертония</kwd><kwd>автономность</kwd><kwd>комплексная гериатрическая оценка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>frailty</kwd><kwd>hypertension</kwd><kwd>autonomy</kwd><kwd>comprehensive geriatric assessment</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена в рамках выполне¬ния государственного задания ОСП РГНКЦ ФГБОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России</funding-statement><funding-statement xml:lang="en">The paper is prepared within the State Governmental Task of the Russian Clinical and Research Center of Gerontology, Pirogov National Research Medical University</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">National Institute on Aging, National Institutes of Health. Global Health and Aging. NIH Publication no. 11–7737. Washington, DC: World Health Organization, 2011.</mixed-citation><mixed-citation xml:lang="en">National Institute on Aging, National Institutes of Health. Global Health and Aging. NIH Publication no. 11–7737. Washington, DC: World Health Organization, 2011.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">[Electronic resource] Health at a Glance 2009. OECD indicators. 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