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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2020-26-1-37-42</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1860</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Распространенность артериальной гипертензии и ортостатической гипотонии у супердолгожителей: предварительные результаты московского исследования 100-летних</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence and coincidence of hypertension and orthostatic hypotension in pre- and centenarians and their effect on mortality: preliminary results of Moscow centenarian study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0048-268X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ерусланова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Eruslanova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ерусланова Ксения Алексеевна — младший научный сотрудник лаборатории сердечно-сосудистого старения </p><p>ул. 1-я Леонова, д. 16, Москва, 129226</p></bio><bio xml:lang="en"><p>Kseniia A. Eruslanova, MD, MSc, Researcher, Laboratory of General Gerontology and Neuro-gerontology, Russian Clinical and Research Center of Gerontology</p><p>16 1st Leonova street, Moscow, 129226</p></bio><email xlink:type="simple">kae.07@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2028-3939</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мачехина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Matchekhina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мачехина Любовь Викторовна — кандидат медицинский наук, научный сотрудник лаборатории возрастных метаболических и эндокринных нарушений </p><p>Москва</p></bio><bio xml:lang="en"><p>Lubov V. Matchekhina, MD, PhD, Senior Researcher, Laboratory of Endocrinology, Russian Clinical and Research Center of Gerontology</p><p>Moscow</p></bio><email xlink:type="simple">mlv66@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1628-5093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котовская</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotovskaya</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котовская Юлия Викторовна — доктор медицинских наук, профессор, заместитель директора по научной работе</p><p>Москва</p></bio><bio xml:lang="en"><p>Yulia V. Kotovskaya, MD, PhD, DSc, Professor, Deputy Director, Russian Clinical and Research Center of Gerontology, Head, Laboratory of Cardiovascular Ageing</p><p>Moscow</p></bio><email xlink:type="simple">kotovskaya@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5272-0454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рунихина</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Runikhina</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рунихина Надежда Константиновна — доктор медицинских наук, профессор, заместитель директора по гериатрической работе</p><p>Москва</p></bio><bio xml:lang="en"><p>Nadezhda K. Runikhina, MD, PhD, DSc, Professor, Deputy Director, Russian Clinical and Research Center of Gerontology, Head, Laboratory of Ambulatory Geriatrics</p><p>Moscow</p></bio><email xlink:type="simple">nkrunihina@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткачева Ольга Николаевна — доктор медицинских наук, профессор, директор </p><p>Москва</p></bio><bio xml:lang="en"><p>Olga N. Tkacheva, MD, PhD, DSc, Professor, Director, Russian Clinical and Research Center of Gerontology</p><p>Moscow</p></bio><email xlink:type="simple">tkacheva@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н. И. Пирогова» Минздрава России, Российский геронтологический научно-клинический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (RNRMU)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2019</year></pub-date><volume>26</volume><issue>1</issue><fpage>37</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ерусланова К.А., Мачехина Л.В., Котовская Ю.В., Рунихина Н.К., Ткачева О.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ерусланова К.А., Мачехина Л.В., Котовская Ю.В., Рунихина Н.К., Ткачева О.Н.</copyright-holder><copyright-holder xml:lang="en">Eruslanova K.A., Matchekhina L.V., Kotovskaya Y.V., Runikhina N.K., Tkacheva O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1860">https://htn.almazovcentre.ru/jour/article/view/1860</self-uri><abstract><p>Цель исследования — оценить распространенность и влияние на смертность артериальной гипертензии (АГ) и ортостатической гипотонии (ОГ) у супердолгожителей (95 лет и старше) города Москвы.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Участниками исследования стали 82 супердолгожителя города Москвы в возрасте от 95 лет и старше (минимальный возраст 95 лет, максимальный — 105 лет), которым на дому была выполнена комплексная гериатрическая оценка мультидисциплинарной командой (врач-гериатр, медицинская сестра и социальный работник). Проспективное наблюдение составило 3 года (36 месяцев).</p></sec><sec><title>Результаты</title><p>Результаты. Анамнез АГ отмечен у 78 %. Среднее систолическое артериальное давление (САД) в положении лежа составило 151 ± 27,9 мм рт. ст. (от 100 до 216 мм рт. ст.), а диастолическое артериальное давление (ДАД) 74 ± 12,8 мм рт. ст. (от 44 до 197 мм рт. ст.). ОГ выявлена у 31 % из 61 долгожителя, выполнившего ортостатическую пробу. Наличие ОГ не было ассоциировано с большим приемом антигипертензивных препаратов. В течение 3 лет умерли 44 участника исследования. Уровень артериального давления (АД), анамнез АГ и наличие ОГ не влияли на смертность (р &gt; 0,05).</p></sec><sec><title>Выводы</title><p>Выводы. У супердолгожителей выявляются широкий диапазон САД и ДАД, высокая распространенность АГ и ОГ. Уровень АД, наличие АГ и ОГ не влияли на смертность в течение 3 лет. Необходимо проведение дополнительных исследований для лучшего понимания состояния здоровья долгожителей и факторов, влияющих на прогноз.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To estimate the prevalence and impact on mortality of arterial hypertension (HTN) and orthostatic hypotension (OH) in centenarians (95 years and older) in Moscow.</p></sec><sec><title>Design and methods</title><p>Design and methods. The study participants were 82 super-long-livers of Moscow city aged 95 years and older (minimum age of 95 years, maximum 105 years), who underwent a comprehensive geriatric assessment at home by a multidisciplinary team (geriatrician, nurse and social worker). The following prospective observation lasted for three years (36 months).</p></sec><sec><title>Results</title><p>Results. Past medical history of HTN was noted in 78 %. The mean systolic blood pressure (SBP) in the supine position was 151 ± 27,9 mm Hg (100–216 mm Hg), and the diastolic blood pressure (DBP) 74 ± 12,8 mm Hg (44–197 mm Hg). OH was detected in 31 % of 61 long-livers who was able to perform an orthostatic test. The presence of OH was not associated with the higher intake of antihypertensive drugs. Within three years, 44 study participants died. The level of blood pressure (BP), history of HTN, and the presence of OH did not affect mortality (p &gt; 0,05).</p></sec><sec><title>Conclusions</title><p>Conclusions. Centenarians have a wide range of SBP and DBP, high prevalence of HTN and OH. BP level, presence of HTN and OH did not affect mortality over 3 year period. Further investigation is needed to understand better the health status of long-livers and factors affecting the prognosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гериатрия</kwd><kwd>долгожители</kwd><kwd>ортостатическая гипотония</kwd><kwd>артериальная гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>geriatrics</kwd><kwd>centenarians</kwd><kwd>orthostatic hypotension</kwd><kwd>hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organisation (WHO). Global Health Observatory (GHO) data. Raised blood pressure. [Electronic resource]. 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