arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2020-26-3-317-326arthyper-1979Research ArticleОБЗОРЫREVIEWSНеврологические и психические расстройства, ассоциированные с COVID-19Neurological and mental disorders associated with COVID-19https://orcid.org/0000-0001-8469-1635НовиковаЛ. Б.NovikovaL. B.

Новикова Лилия Бареевна — доктор медицинских наук, профессор, заведующая кафедрой неврологии института дополнительного профессионального образования (ИДПО)

ул. Ленина, д. 3, Уфа, 450008Тел.: 8(347)255–10–38

Liliia B. Novikova, MD, PhD, DSc, Professor, Head, Department of Neurology, Institute for Continuing Professional Education (ICPE)

3 Lenin street, Ufa, 450008Phone: 8(347)255–10–38

novicova@inbox.ruhttps://orcid.org/0000-0001-8436-5610АкопянА. П.AkopianA. P.

Акопян Анаит Погосовна — кандидат медицинских наук, доцент кафедры неврологии ИДПО

Уфа

Anait P. Akopian, MD, PhD, Associate Professor, Department of Neurology, ICPE

Ufa

ano-akopian@yandex.ruhttps://orcid.org/0000-0002-8552-6233ШараповаК. М.SharapovaK. M.

Шарапова Карина Маратовна — ассистент кафедры неврологии ИДПО

Уфа

Karina M. Sharapova, MD, Assistant, Department of Neurology, ICPE

Ufa

sharapovakarina.2020@gmail.comhttps://orcid.org/0000-0001-7231-8534ЛатыповаР. Ф.LatypovaR. F.

Латыпова Раушания Фанисовна — ассистент кафедры неврологии ИДПО

Уфа

Raushaniya F. Latypova, MD, Assistant, Department of Neurology, ICPE

Ufa

rau.lat@yandex.ruФедеральное государственное образовательное учреждение высшего образования «Башкирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияBashkir State Medical UniversityRussian Federation202016062020263317326Copyright © Новикова Л.Б., Акопян А.П., Шарапова К.М., Латыпова Р.Ф., 20202020Новикова Л.Б., Акопян А.П., Шарапова К.М., Латыпова Р.Ф.Novikova L.B., Akopian A.P., Sharapova K.M., Latypova R.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/1979

В статье представлен обзор научной литературы, клинических наблюдений, содержащий данные о патогенезе, особенностях неврологических проявлений и психических расстройств, осложнениях со стороны нервной системы при новой коронавирусной инфекции, иллюстрированный клиническими примерами. Неврологические нарушения возникают примерно у 36,4 % пациентов с COVID-19. В последнее время описаны тяжелый вирусный геморрагический энцефалит, токсическая энцефалопатия, острые демиелинизирующие поражения периферической нервной системы, острые нарушения мозгового кровообращения, расстройства в поведенческой и эмоциональной сфере. Несмотря на многочисленные публикации о поражении нервной системы, в контексте эпидемии COVID-19 остаются неясными вопросы патогенеза, наличия факторов риска, аргументированной связи неврологических расстройств с коронавирусной инфекцией. Несомненно, необходима систематизация накопленных данных о поражении нервной системы в период эпидемии COVID-19 для их использования в практической работе невролога, дальнейшей разработки оптимальной стратегии лечения и осуществления эффективных профилактических мероприятий.

The article presents a narrative review, clinical observations. Special attention is given to the pathogenesis, features of neurological manifestations and mental disorders, neurological complications in coronavirus infection, illustrated by clinical cases. Neurological disorders occur in approximately 36,4 % patients with COVID-19. Currently, severe viral hemorrhagic encephalitis, toxic encephalopathy, acute demyelinating lesions of the peripheral nervous system, stroke, behavioral and emotional disorders have been described. Despite numerous publications on the neurological pathology in COVID-19, pathogenesis, risk factors, and relation between neurological disorders and coronavirus infection remain unclear. There is a need for systematization of the accumulated data on the damage to the nervous system during the COVID-19 epidemic for clinical routine use, further development of the optimal treatment strategy and implementation of effective preventive measures.

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The authors declare that there are no conflicts of interest present.