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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2021-27-1-110-116</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-1998</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Этиологическая структура и коморбидность кардиоэмболического инсульта</article-title><trans-title-group xml:lang="en"><trans-title>Etiological structure and comorbidity of cardioembolic stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2233-0257</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чухловина</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Chukhlovina</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чухловина Мария Лазаревна — доктор медицинских наук, профессор кафедры неврологии и психиатрии.</p><p>Ул. Аккуратова, д. 2, Санкт-Петербург, 197341</p></bio><bio xml:lang="en"><p>Mariya L. Chukhlovina - MD, PhD, DSc, Professor,  Department of Neurology and Psychiatry.</p><p>2 Akkuratova street, St Petersburg, 197341</p></bio><email xlink:type="simple">alexei.chukh@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4441-1165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Татьяна Михайловна — доктор медицинских наук, доцент, заведующая кафедрой неврологии и психиатрии.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Tat’ayna M. Alekseeva - MD, PhD, DSc, Associate Professor, Head, Department of Neurology and Psychiatry.</p><p>St Petersburg</p></bio><email xlink:type="simple">alekseeva_tm@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8695-2816</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Екатерина Сергеевна — клинический ординатор кафедры неврологии и психиатрии.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Ekaterina S. Efremova - MD, Resident, Department of Neurology and Psychiatry.</p><p>St Petersburg</p></bio><email xlink:type="simple">catharinaephraim@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение Национальный медицинский исследовательский центр  имени В.А. Алмазова Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>07</day><month>04</month><year>2021</year></pub-date><volume>27</volume><issue>1</issue><fpage>110</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чухловина М.Л., Алексеева Т.М., Ефремова Е.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Чухловина М.Л., Алексеева Т.М., Ефремова Е.С.</copyright-holder><copyright-holder xml:lang="en">Chukhlovina M.L., Alekseeva T.M., Efremova E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/1998">https://htn.almazovcentre.ru/jour/article/view/1998</self-uri><abstract><p>В последнее время в структуре инсульта все более значимая доля отводится кардиоэмболическому (КЭ) подтипу. В связи с этим возникает вопрос о причинах КЭ инсульта на современном этапе. Клинический опыт свидетельствует, что наличие коморбидных расстройств оказывает большое влияние на течение заболевания, его раннюю диагностику, терапию и прогноз. При этом данные о структуре КЭ инсульта и коморбидных состояниях немногочисленны и противоречивы.</p><p>Целью работы было изучение этиологической структуры КЭ инсульта и его коморбидности на основе работы Регионального сосудистого центра.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 62 больных в остром периоде ишемического инсульта в возрасте от 44 до 96 лет. Для оценки ожидаемого риска инсульта за год у обследованных больных была использована шкала CHA2DS2-VASc. Результаты исследования свидетельствуют, что в этиологической структуре КЭ инсульта доминирует фибрилляция предсердий, затем следует острый инфаркт миокарда. Установлено, что, по сравнению с атеротромботическим инсультом, КЭ инсульт отличается более высоким индексом коморбидности, что, видимо, является одним из факторов, ухудшающим его прогноз. Определение суммарного балла по шкале CHA2DS2-VASc у пациентов, перенесших КЭ инсульт, показало высокий риск повторного острого нарушения мозгового кровообращения.</p></sec><sec><title>Заключение</title><p>Заключение. В связи с вышесказанным необходим междисциплинарный подход к диагностическому и лечебному процессу с участием кардиолога и невролога для повышения эффективности терапии и улучшения прогноза заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. Cardioembolic (CE) subtype has recently become increasingly important in the structure of brain stroke. This raises the question about the causes of CE stroke at the present stage. Clinical experience shows that the presence of comorbid disorders has a great influence on the course, early diagnosis, therapy and prognosis of the disease. However, the data on the structure of CE stroke and comorbid disorders are contradictory. This article aimed at studying etiological structure of CE stroke and its comorbidities.</p></sec><sec><title>Design and methods</title><p>Design and methods. The study included 62 patients at the acute phase of ischemic stroke aged from 44 to 96 years. The CHA2DS2-VASc scale was used to evaluate the expected annual stroke risk. Results. Our data show that the etiological structure of the CE stroke is presented predominantly by atrial fibrillation, followed by acute myocardial infarction. Compared to atherothrombotic stroke, the CE stroke was found to have a higher comorbidity index. CHA2DS2-VASc total score in patients with CE stroke showed a high risk of recurrent acute cerebrovascular accident.</p></sec><sec><title>Conclusions</title><p>Conclusions. Thus, an interdisciplinary approach to the diagnostic and treatment process involving a cardiologist and neurologist is required in order to improve the effectiveness of therapy and prognosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>кардиоэмболический инсульт</kwd><kwd>коморбидность</kwd><kwd>структура инсульта</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>cardioembolic stroke</kwd><kwd>comorbidity</kwd><kwd>etiological structure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шляхто Е. В., Звартау Н. Э., Виллевальде С. В., Яковлев А. Н., Соловьева А. Е., Авдонина Н. Г. 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