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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2020-26-4-468-484</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2002</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>COVID-19: каковы риски для пациентов с нарушениями сна?</article-title><trans-title-group xml:lang="en"><trans-title>COVID-19: what are the risks for patients with sleep disorders?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростовцева</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korostovtseva</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коростовцева Людмила Сергеевна — кандидат медицинских наук, старший научный сотрудник группы по сомнологии научно-исследовательского отдела артериальной гипертензии, доцент кафедры кардиологии.</p></bio><bio xml:lang="en"><p>Lyudmila S. Korostovtseva, MD, PhD, Senior Researcher, Somnology Group, Research Department for Hypertension, Associate Professor, Faculty Department of Cardiology, Almazov NMRC.</p></bio><email xlink:type="simple">ag_journal@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7408-9613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочкарев</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochkarev</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бочкарев Михаил Викторович — кандидат медицинских наук, старший научный сотрудник группы по сомнологии на-учно-исследовательского отдела артериальной гипертензии.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Mikhail V. Bochkarev, MD, PhD, Senior Researcher, Somnology Group, Research Department for Hypertension.</p><p>St Petersburg</p></bio><email xlink:type="simple">bochkarev_mv@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шумейко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shumeyko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шумейко Анастасия Александровна — лаборант-иссле-дователь группы по сомнологии научно-исследовательского отдела артериальной гипертензии.</p></bio><bio xml:lang="en"><p>AnastasiaA. Shumeyko - MD, Laboratory Assistant, Somnology Group, Research Department for Hypertension.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучеренко</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucherenko</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кучеренко Наталия Григорьевна — кандидат медицинских наук, руководитель Центра респираторной терапии и сомнологии ФГБУ СЗОНКЦ им. Л. Г. Соколова ФМБА России, ассистент кафедры госпитальной терапии и кардиологии им. М. С. Кушаковского СЗГМУ им. И. И. Мечникова.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Natalia G. Kucherenko - MD, PhD, Head, Center of Respiratory Therapy and Somnology, North-Western Regional Medical Research Center named after L. G. Sokolov; Assistant, Department of Internal Diseases and Cardiology n. a. M.S. Kushakovskiy, NWRMRC named after I. I. Mechnikov.</p></bio><email xlink:type="simple">nataliadoc@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бебех</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bebekh</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бебех Антон Николаевич—аспирант кафедры госпитальной терапии и кардиологии им. М. С. Кушаковского СЗГМУ им. И. И. Мечникова; врач-терапевт ФГБУ СЗОНКЦ им. Л. Г. Соколова ФМБА России.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Anton N. Bebekh - MD, PhD Student, Assistant, Department of Internal Diseases and Cardiology n. a. M. S. Kushakovskiy, North-Western State Medical University named after I.I. Mechnikov; Physician, NWRMRC named after L. G. Sokolov.</p><p>St Petersburg</p></bio><email xlink:type="simple">vizier3@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горелов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorelov</surname><given-names>А. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Горелов Александр Игоревич—доктор медицинских наук, профессор, главный терапевт, заведующий терапевтическим отделением ФГБУ СЗОНКЦ им. Л.Г. Соколова ФМБА России, профессор кафедры госпитальной терапии и кардиологии им. М. С. Кушаковского СЗГМУ им. И.И. Мечникова.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Alexander I. Gorelov - MD, PhD, DSc, Professor, Main Physician, Head, Department of Internal Diseases, North-Western Regional Medical Research Center named after L. G. Sokolov; Professor, Department of Internal Diseases and Cardiology n. a. M.S. Kushakovskiy, NWSMUnamed after I. I. Mechnikov.</p><p>St Petersburg</p></bio><email xlink:type="simple">prof.gorelov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3170-0451</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свиряев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sviryaev</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Свиряев Юрий Владимирович — доктор медицинских наук, руководитель группы по сомнологии научно-исследовательского отдела артериальной гипертензии НМИЦ им. В. А. Алмазова, руководитель лаборатории сравнительной сомнологии и нейроэндокринологии ИЭФБ им. И. М. Сеченова РАН.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Yurii V Sviryaev - MD, PhD, DSc, Head, Somnology Group, Research Department for Hypertension, Almazov NMRC; Head, Laboratory of Comparative Somnology and Neuroendocrinology, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences.</p><p>St Petersburg</p></bio><email xlink:type="simple">sviryaev_yuv@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8169-7812</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Конради Александра Олеговна — доктор медицинских наук, профессор, руководитель НИО АГ, заместитель генерального директора по научной работе НМИЦ им. В. А. Алмазова, руководитель Института трансляционной медицины Университета ИТМО.</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Aleksandra O. Konradi - MD, PhD, DSc, Professor, Head, Research Department for Arterial Hypertension, Deputy General Director on Research, Almazov NMRC; Head; Institute of Translational Medicine, ITMO University.</p><p>St Petersburg</p></bio><email xlink:type="simple">konradi_ao@almazovcentre.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение Национальный медицинский исследовательский центр имени В.А. Алмазова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение Северо-Западный окружной научно-клинический центр имени Л.Г. Соколова Федерального медико-биологического агентства; Федеральное государственное бюджетное образовательное учреждение высшего образования Северо-Западный государственный медицинский университет имени И.И. Мечникова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western Regional Medical Research Center named after L.G. Sokolov; North-Western State Medical University named after I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение Национальный медицинский исследовательский центр имени В.А. Алмазова Минздрава России; Федеральное государственное бюджетное учреждение науки Институт эволюционной физиологии и биохимии имени И.М. Сеченова Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre; Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение Национальный медицинский исследовательский центр имени В.А. Алмазова Минздрава России; Университет ИТМО</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre; ITMO University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>08</month><year>2020</year></pub-date><volume>26</volume><issue>4</issue><fpage>468</fpage><lpage>484</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коростовцева Л.С., Бочкарев М.В., Шумейко А.А., Кучеренко Н.Г., Бебех А.Н., Горелов А.И., Свиряев Ю.В., Конради А.О., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Коростовцева Л.С., Бочкарев М.В., Шумейко А.А., Кучеренко Н.Г., Бебех А.Н., Горелов А.И., Свиряев Ю.В., Конради А.О.</copyright-holder><copyright-holder xml:lang="en">Korostovtseva L.S., Bochkarev M.V., Shumeyko A.A., Kucherenko N.G., Bebekh A.N., Gorelov А.I., Sviryaev Y.V., Konradi A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2002">https://htn.almazovcentre.ru/jour/article/view/2002</self-uri><abstract><p>Коронавирусная пандемия внесла значительные изменения в жизнь людей во всем мире, и бороться с последствиями этих изменений — медицинскими, социальными, психологическими, экономическими и прочими—предстоит еще на протяжении не одного месяца. В период, когда отмечается снижение темпов стремительного роста заболеваемости инфекцией, вызванной вирусом SARS-CoV-2, на первый план выходят новые вопросы, касающиеся долгосрочного прогноза и реабилитации пациентов, перенесших данную инфекцию, стойкости иммунитета и возможности повторного заражения, подходов к профилактике новых случаев инфекции, повышения иммунитета. Ожидается увеличение числа случаев стресс-ассоциированных соматических и психических заболеваний в долгосрочной перспективе, в том числе и нарушений сна, что обусловлено целым рядом причин, действующим в период пандемии (изменение привычного образа жизни, режима работы, снижение физической активности в условиях самоизоляции, увеличение времени воздействия искусственного освещения, в том числе от экранов компьютеров, мобильных телефонов, и многие другие факторы). Полученные к настоящему времени данные говорят о существенном вкладе сна в состояние здоровья и благополучие населения. В статье суммированы данные, свидетельствующие о роли сна в регуляции иммунной системы. Особое внимание уделено нарушениям дыхания во время сна, которые ассоциированы с повышением риска как инфицирования SARS-CoV-2, так и более тяжелого течения заболевания, а также другим изменениям качества и продолжительности сна, наблюдаемым в период пандемии. Освещены подходы к коррекции возникающих в стрессовой ситуации нарушений сна, которые могут способствовать как более успешной реабилитации выздоравливающих после перенесенного COVID-19 пациентов, так и укреплению здоровья населения, подвергнувшегося стрессовому воздействию.</p></abstract><trans-abstract xml:lang="en"><p>Coronavirus pandemic significantly changed our lives, leading to long-lasting medical, social, economic, psychological consequences. Currently, when the COVID-19 morbidity growth is less galloping, the more important are the issues of long-lasting prognosis, rehabilitation, immunity stability, risk of recurrent infection etc. An increased incidence of stress-induced somatic and mental diseases is envisaged. Among them, sleep disorders appear to be significant and can result from various reasons: change in habitual life style, work regimen, decrease in physical activity during self-isolation, lesser daylight exposure and greater exposure to artificial light (including screens of electronic devices). The evidence confirms an important role of sleep in human health and wellbeing. The paper summarizes data on the role of sleep in immune system regulation. We pay special attention to sleep-disordered breathing which is associated with the higher risk of infection by SARS-CoV-2 and more severe COVID-19. Other sleep disorders, including changes in sleep quality and duration during the pandemic, are also discussed. The paper reviews the existing approaches to manage stress-induced sleep disorders which are applicable in the pandemic and can be implemented in rehabilitation procedures.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>сон</kwd><kwd>нарушения сна</kwd><kwd>инсомния</kwd><kwd>качество сна</kwd><kwd>реабилитация</kwd><kwd>хронотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronavirus infection</kwd><kwd>COVID-19</kwd><kwd>sleep</kwd><kwd>sleep disorders</kwd><kwd>insomnia</kwd><kwd>sleep quality</kwd><kwd>rehabilitation</kwd><kwd>chronotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lee L, Iyer S, Jose RJ, Manuel A. COVID-19 follow-up planning: what will we be missing? 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