arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2021-27-3-300-308arthyper-2053Research ArticleОБЗОРREVIEWПоказатели жесткости аорты при дегенеративном аортальном стенозеAortic stiffness in degenerative aortic stenosishttps://orcid.org/0000-0002-6516-3180ПротасовК. В.ProtasovK. V.

Протасов Константин Викторович — доктор медицинских наук, профессор, заместитель директора по науке и развитию, заведующий кафедрой кардиологии и функциональной диагностики

Иркутск

Konstantin V. Protasov, MD, PhD, DSc, Professor, Vice-Director for Research, Head, Cardiology and Functional DiagnosticsDepartment

Irkutsk

protassov_k@rambler.ruhttps://orcid.org/0000-0002-0486-9657МакароваА. С.MakarovaA. S.

Макарова Александра Сергеевна — аспирант кафедры кардиологии и функциональной диагностики Иркутской  ГМАПО — филиала ФГБОУ ДПО РМАНПО Минздрава  России, врач-кардиолог кардиохирургического отделения № 1 ГБУЗ «Иркутская областная ордена «Знак Почета» клиническая больница»

Микрорайон Юбилейный-100, Иркутск, 664049. Тел.: 8(3952)46–11–35

Alexandra S. Makarova, MD, Postgraduate Student, Cardiology and Functional Diagnostics Department, Irkutsk State Medical Academy of Postgraduate Education, Cardiologist of Cardiosurgical Department, Irkutsk Regional Clinical Hospital

Microdistrict Yubileiny-100, Irkutsk, 664049. Phone: 8(3952)46–11–35

MakarovaAlexandraS@yandex.ruhttps://orcid.org/0000-0002-5333-0850БатёхаВ. И.BatekhaV. I.

Батёха Вячеслав Игоревич — врач-сердечно-сосудистый хирург кардиохирургического отделения № 1

Иркутск

Vyacheslav I. Batekha, MD, Cardiovascular Surgeon, Cardiosurgical Department

Irkutsk

bateha_vi@mail.ruhttps://orcid.org/0000-0002-3269-0195ЖелтовскийЮ. В.ZheltovskiyY. V.

Желтовский Юрий Всеволодович — доктор медицинских наук, профессор, заведующий кафедрой сердечно-сосудистой хирургии и клинической ангиологии Иркутской ГМАПО — филиала ФГБОУ ДПО РМАНПО Минздрава России, заведующий кардиохирургическим отделением № 1 ГБУЗ «Иркутская областная ордена «Знак Почета» клиническая больница»

Иркутск

Yuri V. Zheltovskiy, MD, PhD, DSc, Professor, Head, Cardiovascular Surgery and Clinical Angiology Department, Irkutsk State Medical Academy of Postgraduate Education, Head, Cardiosurgical Department, Irkutsk Regional Clinical Hospital

Irkutsk

jeltoff@mail.ruИркутская государственная медицинская академия последипломного образования — филиал федерального государственного бюджетного образовательного учреждения дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской ФедерацииРоссияIrkutsk State Medical Academy of Postgraduate EducationRussian FederationИркутская государственная медицинская академия последипломного образования — филиал федерального государственного бюджетного образовательного учреждения дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения «Иркутская областная ордена «Знак Почета» клиническая больница»РоссияIrkutsk State Medical Academy of Postgraduate Education; Irkutsk Regiona Clinical HospitalRussian FederationГосударственное бюджетное учреждение здравоохранения «Иркутская областная ордена «Знак Почета» клиническая больница»РоссияIrkutsk Regional Clinical HospitalRussian FederationИркутская государственная медицинская академия последипломного образования — филиал федерального государственного бюджетного образовательного учреждения дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской ФедерацииРоссияIrkutsk State Medical Academy of Postgraduate Education; Irkutsk Regiona Clinical HospitalRussian Federation202122072021273300308Copyright © Протасов К.В., Макарова А.С., Батёха В.И., Желтовский Ю.В., 20212021Протасов К.В., Макарова А.С., Батёха В.И., Желтовский Ю.В.Protasov K.V., Makarova A.S., Batekha V.I., Zheltovskiy Y.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/2053

Аортальный стеноз (АС) является одним из наиболее распространенных сердечно-сосудистых заболеваний. Распространенность АС и сосудистая жесткость ассоциированы с возрастом. Повышенная артериальная жесткость является независимым фактором риска сердечно-сосудистых событий. Патогенетические и клинические взаимосвязи дегенеративного АС и жесткости аорты мало изучены. В настоящем обзоре отражены современные представления о взаимосвязях дегенеративного АС и аортальной ригидности. Описаны результаты исследований о влиянии хирургической и эндоваскулярной коррекции порока на показатели жесткости аорты. Обсуждены возможности их использования для прогноза течения АС и исходов протезирования клапана. Определены нерешенные вопросы и направления дальнейших исследований в этой области.

Aortic stenosis (AS) is one of the most common cardiovascular diseases. The prevalence of AS and vascular stiffness are significantly associated with age. Elevated arterial stiffness is an independent risk factor for cardiovascular events. The pathogenetic and clinical relationship of degenerative AS and aortic stiffness is poorly known. This review reflects the current understanding of the relationship between degenerative AS and aortic stiffness. The existing evidence on the effects of surgical and endovascular correction of the defect on aortic stiffness is described. The potential predictors of AS prognosis and outcomes of valve replacement are discussed. Unresolved issues and directions for further research are clarified.

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The authors declare that there are no conflicts of interest present.