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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2022-28-6-614-626</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2234</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры и лекции</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Биохимические и молекулярно-генетические маркеры повреждения почек при артериальной гипертензии</article-title><trans-title-group xml:lang="en"><trans-title>Biochemical and molecular genetic markers of kidney damage in hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4892-0861</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спиридонов</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Spiridonov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Спиридонов Александр Николаевич — врач-ординатор по специальности «Кардиология» НИИТПМ – филиал ИЦиГ СО РАН</p><p>ул. Бориса Богаткова, д. 175/1, Новосибирск, 630089.</p><p> </p></bio><bio xml:lang="en"><p>Aleksandr N. Spiridonov, Doctor Resident in the Specialty “Cardiology”</p><p>175/1 Borisa Bogatkova str., Novosibirsk, 630089</p></bio><email xlink:type="simple">Spiridonov.al16@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7875-1566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Худякова</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Khudiakova</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Худякова Алена Дмитриевна — кандидат медицинских наук, руководитель лаборатории генетических и средовых де- терминант жизненного цикла человека НИИТПМ – филиал ИЦиГ СО РАН</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Alena D. Khudiakova, PhD, Head of the Laboratory of Genetic and Environmental Determinants of the Human Life Cycle</p><p>Novosibirsk</p></bio><email xlink:type="simple">alene.elene@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5316-4664</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрюкова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Striukova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Стрюкова Евгения Витальевна — кандидат медицинских наук, научный сотрудник лаборатории клинических биохимических и гормональных исследований терапевтических заболеваний НИИТПМ – филиал ИЦиГ СО РАН</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Evgeniia V. Striukova, PhD, Researcher at the Laboratory of Clinical Biochemical and hormonal studies of Therapeutic Diseases</p><p>Novosibirsk</p></bio><email xlink:type="simple">stryukova.j@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт  терапии и профилактической медицины — филиал Федерального государственного бюджетного научного учреждения&#13;
«Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии  наук»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Internal and Preventive Medicine — Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>01</day><month>08</month><year>2022</year></pub-date><volume>28</volume><issue>6</issue><fpage>614</fpage><lpage>626</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Спиридонов А.Н., Худякова А.Д., Стрюкова Е.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Спиридонов А.Н., Худякова А.Д., Стрюкова Е.В.</copyright-holder><copyright-holder xml:lang="en">Spiridonov A.N., Khudiakova A.D., Striukova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2234">https://htn.almazovcentre.ru/jour/article/view/2234</self-uri><abstract><p>В настоящем обзоре представлены результаты исследований в области изучения ассоциаций биохимических и молекулярно-генетических маркеров повреждения почек при артериальной гипертензии. Использованы сведения по теме из публикаций баз данных PubMed, Google Scholar.</p></abstract><trans-abstract xml:lang="en"><p>This review presents the results of research in the field of studying associations of biochemical and molecular genetic markers of kidney damage in arterial hypertension. Information on the topic from publications of PubMed, Google Scholar databases was used. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>биохимические маркеры</kwd><kwd>гипертоническая нефропатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>biochemical markers</kwd><kwd>hypertensive nephropathy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Литературный обзор выполнен в рамках бюджетной темы «Формирование когорт детского, подросткового, молодого населения для изучения механизмов и особенностей жизненного цикла человека в российской популяции». Регистрационный номер 122031700115–7.</funding-statement><funding-statement xml:lang="en">The literature review was carried out within the framework of the budget topic “Formation of cohorts of children, adolescents, and young people to study the mechanisms and features of the human life cycle in the Russian population”. Registration number 122031700115–7.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Seccia TM, Caroccia B, Calò LA. Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms. J Hypertens. 2017;35(2):205–212. doi:10.1097/HJH.0000000000001170</mixed-citation><mixed-citation xml:lang="en">Seccia TM, Caroccia B, Calò LA. Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms. 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