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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2022-28-6-718-727</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2245</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Первый случай успешного применения низкопрофильного потокперенаправляющего стента в лечении инфекционной церебральной аневризмы у пациентки с механическим клапаном сердца. Клиническое наблюдение и обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>First case of successful usage of a low-profile flow-diverting stent for treatment of intracranial infectious aneurysm in patient with a mechanical heart valve. Clinical case and literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3904-2393</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коломин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolomin</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коломин Егор Геннадьевич — врач-нейрохирург нейрохирургического отделения № 3, младший научный сотрудник научно-исследовательской лаборатории хирургии сосудов головного и спинного мозга </p><p>ул. Маяковская, д. 12, Санкт-Петербург, 191014</p></bio><bio xml:lang="en"><p>Egor G. Kolomin, neurosurgeon of the neurosurgical department no. 3, junior researcher at the research laboratory of surgery of cerebral and spinal vessels </p><p>12 Mayakovskaya street, St Petersburg, 191014 </p></bio><email xlink:type="simple">neurokolomin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0974-460X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожченко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhchenko</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рожченко Лариса Витальевна — кандидат медицинских наук, руководитель научно-исследовательской лаборатории хирургии сосудов головного и спинного мозга, врач-нейрохирург нейрохирургического отделения № 3, </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Larisa V. Rozhchenko, MD, PhD, head of research laboratory of surgery of cerebral and spinal vessels, neurosurgeon of the neurosurgical department No. 3</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0956-6994</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бобинов</surname><given-names>В. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Bobinov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бобинов Василий Витальевич — научный сотрудник НИЛ хирургии сосудов головного и спинного мозга, врачнейрохирург нейрохирургического отделения № 3</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vasiliy V. Bobinov, researcher of research laboratory of surgery of cerebral and spinal vessels, neurosurgeon of the neurosurgical department No. 3,</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7297-3213</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горощенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Goroshchenko</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Горощенко Сергей Анатольевич — кандидат медицинских наук, старший научный сотрудник НИЛ хирургии сосудов головного и спинного мозга, врач-нейрохирург нейрохирургического отделения № 3 </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Sergey A. Goroshchenko, MD, PhD, senior researcher of research laboratory of surgery of cerebral and spinal vessels, neurosurgeon of the neurosurgical department No. 3</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3112-6584</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Андрей Евгеньевич — врач-нейрохирург, заведующий нейрохирургическим отделения № 3</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Andrey E. Petrov, neurosurgeon and head of the neurosurgical department no. 3</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4952-2219</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фролова Ольга Андреевна — врач-терапевт </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Olga A. Frolova, therapist</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5295-4912</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самочерных</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Samochernykh</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самочерных Константин Александрович — доктор медицинских наук, директор </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Konstantin A. Samochernykh, MD, PhD, DSc, Professor, Director</p><p>St Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский  научно-исследовательский  нейрохирургический институт имени профессора А. Л. Поленова — филиал Федеральное государственное бюджетное учреждение «Национальный  медицинский  исследовательский  центр имени В. А. Алмазова» Министерства здравоохранения  Российской  Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polenov Research Neurosurgical Institute — branch of Almazov National Medical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>22</day><month>11</month><year>2022</year></pub-date><volume>28</volume><issue>6</issue><fpage>718</fpage><lpage>727</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коломин Е.Г., Рожченко Л.В., Бобинов В.B., Горощенко С.А., Петров А.Е., Фролова О.А., Самочерных К.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Коломин Е.Г., Рожченко Л.В., Бобинов В.B., Горощенко С.А., Петров А.Е., Фролова О.А., Самочерных К.А.</copyright-holder><copyright-holder xml:lang="en">Kolomin E.G., Rozhchenko L.V., Bobinov V.V., Goroshchenko S.A., Petrov A.E., Frolova O.A., Samochernykh K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2245">https://htn.almazovcentre.ru/jour/article/view/2245</self-uri><abstract><p>Инфекционные аневризмы (ИА) — это церебральные аневризмы, формирующиеся вследствие инфекционного воспаления стенки артерии. Они являются достаточно редкой патологией и в большинстве случаев — осложнением инфекционного (бактериального) эндокардита левых камер сердца. Своевременная диагностика ИА в догеморрагическом периоде является проблематичной из-за вариабельности клинической картины ИА, стертого или малосимптомного клинического течения, возможности формирования ИА в отдаленном периоде после септических эмболий, даже на фоне проводимой антибактериальной терапии. Представленный клинический случай иллюстрирует первое успешное применение низкопрофильного потокотклоняющего стента для лечения пациентки молодого возраста с механическим клапаном сердца и ИА левой средней мозговой артерии, развившейся на месте септической эмболии в остром периоде септического бактериального эндокардита, сопровождавшегося ишемическим инсультом. Данное наблюдение демонстрирует эффективность выбранного метода лечения, особенности адекватной предоперационной подготовки, возможные послеоперационные осложнения и детализированную коррекцию антикоагулянтной и дезагрегантной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Infectious aneurysms (IA) are cerebral aneurysms that are formed due to the infectious inflammation of the arterial wall. They are a rather rare pathology and in most cases prove to be a complication of infectious (bacterial) endocarditis of the left heart chambers. Timely diagnosis of IA in the pre-hemorrhagic period is problematic due to the variability of the clinical picture of IA, frequent blurred or low-symptomatic clinical course, the possibility of IA formation in the remote period after septic embolism, even despite the background of antibiotic therapy. The presented clinical case illustrates the first successful use of a low-profile flow-diverting stent for the treatment of a young patient with a mechanical heart valve and an infectious aneurysm of the left middle cerebral artery, developed at the site of septic embolism in the acute period of septic bacterial endocarditis accompanied by ischemic stroke. This observation demonstrates the effectiveness of the chosen method of treatment, peculiarities of adequate preoperative preparation, possible postoperative complications and detailed correction of anticoagulant and antiplatelet therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекционная церебральная аневризма</kwd><kwd>инфекционный эндокардит</kwd><kwd>механический клапан сердца</kwd><kwd>низкопрофильный потокоперенаправляющий стент</kwd><kwd>дезагрегантная и антикоагулянтная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>infectious cerebral aneurysm</kwd><kwd>infective endocarditis</kwd><kwd>mechanical heart valve</kwd><kwd>low-profile flowdiverting stent</kwd><kwd>antiplatelet and anticoagulant therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sonneville R, Mirabel M, Hajage D, Tubach F, Vignon P, Perez P et al. 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