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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2023-29-2-231-240</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2323</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Ингибитор ангиотензинпревращающего фермента, антагонист кальция и диуретик — три ведущих компонента терапии в лечении артериальной гипертензии. Какие преимущества может дать тройная фиксированная комбинация?</article-title><trans-title-group xml:lang="en"><trans-title>ACE-inhibitor, calcium antagonist and diuretic as three major components of antihypertensive therapy. Potential advantages of fixed triple combinations</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8169-7812</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Конради Александра Олеговна — доктор медицинских наук, профессор, академик Российской академии наук, заведующая кафедрой организации, управления и экономики здравоохранения Института медицинского образования, заместитель генерального директора по научной работе ФГБУ «НМИЦ им. В.А. Алмазова» Минздрава России.</p><p>ул. Аккуратова, д. 2, Санкт-Петербург, 197341</p><p>Тел.: 8 (812) 702-37-33</p></bio><bio xml:lang="en"><p>Aleksandra O. Konradi - MD, PhD, DSc, Professor, Academician of the Russian Academy of Sciences, Head, the Department of Organization, Management and Economics of Healthcare of the Institute of Medical Education, Deputy Director General for Scientific Work, Almazov National Medical Research Centre.</p><p>2 Akkuratov str., St Petersburg, 197341</p><p>Phone: 8(812)702-37-33</p></bio><email xlink:type="simple">konradi@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В.А. Алмазова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>05</month><year>2023</year></pub-date><volume>29</volume><issue>2</issue><fpage>231</fpage><lpage>240</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Конради А.О., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Конради А.О.</copyright-holder><copyright-holder xml:lang="en">Konradi A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2323">https://htn.almazovcentre.ru/jour/article/view/2323</self-uri><abstract><p>Статья описывает текущую ситуацию в мире и в России в отношении информированности пациентов о наличии у них артериальной гипертензии и приверженности к лечению. Рассматривается роль тройных фиксированных комбинаций, в частности комбинации амлодипина, индапамида и периндоприла, для повышения комплаентности пациентов и улучшения прогноза.</p></abstract><trans-abstract xml:lang="en"><p>The article describes the current situation in hypertension awareness and treatment, the role of treatment adherence and fixed-dose combinations in its improvement. The real world data form recent studies concerning adherence and outcome on the triple combination of amlodipine/indapamide/perindopril are demonstrated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>фиксированные комбинации препаратов</kwd><kwd>амлодипин</kwd><kwd>индапамид</kwd><kwd>периндоприл</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>fixed combinations</kwd><kwd>amlodipine</kwd><kwd>perindopril</kwd><kwd>indapamide</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена при информационной поддержке компании «Сервье» (Франция), что никоим образом не повлияло на мнение автора и материал статьи.</funding-statement><funding-statement xml:lang="en">The article was prepared with the informational support of the Servier company (France), which in no way affected the opinion of the author and the presented data.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2019 Risk Factors Collaborators. 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