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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2024-2395</article-id><article-id custom-type="edn" pub-id-type="custom">FQXFKU</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2395</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Фибрилляция предсердий и синдром обструктивного апноэ во сне: результаты ретроспективного исследования</article-title><trans-title-group xml:lang="en"><trans-title>Atrial fibrillation and obstructive sleep apnea syndrome: results of a retrospective study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8479-0331</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердышева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdysheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бердышева Виктория Александровна—ассистент кафедры терапии факультетской с курсом эндокринологии, кардиологии с клиникой им. акад. Г. Ф. Ланга</p><p>ул. Льва Толстого, д. 6/8, СанктПетербург, 197022</p></bio><bio xml:lang="en"><p>Viktoria A. Berdysheva, MD, Assistant, Department of Internal Diseases № 2</p><p>6/8 Lev Tolstoy str., St Petersburg, 197022</p></bio><email xlink:type="simple">ilingina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7293-1144</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ионин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ionin</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ионин Валерий Александрович —кандидат медицинских наук, доцент кафедры терапии факультетской с курсом эндокринологии, кардиологии с клиникой им. акад. Г. Ф. Ланга, старший научный сотрудник Научно-исследовательского института сердечно-сосудистых заболеваний Научно-клинического исследовательского центра</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Valery A. Ionin, MD, PhD, Senior Researcher, Associate Professor, Department of Internal Diseases № 2</p><p> St Petersburg</p></bio><email xlink:type="simple">ionin.v.a@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-5604-4741</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вакуленко</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakulenko</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вакуленко Анастасия Сергеевна — студент 6 ‑го курса лечебного факультета</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Anastasia S. Vakulenko, 6th year Student</p><p> St Petersburg</p></bio><email xlink:type="simple">vakullenko@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-4914-4180</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шунчева</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shuncheva</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шунчева Валерия Владимировна —студент 6 ‑го курса лечебного факультета</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Valeria V. Shuncheva, 6th year Student, Medical Faculty</p><p> St Petersburg</p></bio><email xlink:type="simple">lerashuncheva@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-5084-8723</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакулин</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakulin</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бакулин Геннадий Геннадьевич — клинический ординатор кафедры терапии факультетской с курсом эндокринологии, кардиологии с клиникой им. акад. Г. Ф. Ланга</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Gennady G. Bakulin, MD, Resident, Department of Internal Diseases № 2</p><p> St Petersburg</p></bio><email xlink:type="simple">bakulin@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8788-0076</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баранова Елена Ивановна — доктор медицинских наук, профессор кафедры терапии факультетской с курсом эндокринологии, кардиологии с клиникой им. акад. Г. Ф. Ланга</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Elena I. Baranova, MD, PhD, DSc, FESC, Professor, Department of Internal Diseases № 2</p><p> St Petersburg</p></bio><email xlink:type="simple">baranova.grant2015@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>02</month><year>2024</year></pub-date><volume>30</volume><issue>1</issue><fpage>58</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бердышева В.А., Ионин В.А., Вакуленко А.С., Шунчева В.В., Бакулин Г.Г., Баранова Е.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Бердышева В.А., Ионин В.А., Вакуленко А.С., Шунчева В.В., Бакулин Г.Г., Баранова Е.И.</copyright-holder><copyright-holder xml:lang="en">Berdysheva V.A., Ionin V.A., Vakulenko A.S., Shuncheva V.V., Bakulin G.G., Baranova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2395">https://htn.almazovcentre.ru/jour/article/view/2395</self-uri><abstract><p>Цель исследования – изучить встречаемость и факторы риска фибрилляции предсердий (ФП) у пациентов с синдромом обструктивного апноэ сна (СОАС), верифицированным по данным скринингового ночного респираторного мониторирования, выполненного в рамках госпитализации в терапевтический стационар. Материалы и методы. В исследовании выполнен ретроспективный анализ 291 истории болезни пациентов, госпитализированных в терапевтическую клинику в 2021-2022гг. Всем пациентам в рамках первичного скринингового обследования на предмет наличия нарушений дыхания во сне выполнялось ночное респираторное мониторирование. Результаты. Синдром обструктивного апноэ сна был выявлен у 216 больных, легкой степени тяжести – у 27,8%, средней степени – у 20,3%, тяжелой степени – у 26,1% пациентов. Встречаемость фибрилляции предсердий у пациентов с диагностированным СОАС составила 28,7% и была достоверно выше у пациентов с тяжелой степенью апноэ по сравнению с больными с легкой степенью (р=0,043). По результатам анализа причин, лежащих в основе развития ФП у больных с верифицированным апноэ, артериальная гипертензия выявлена у 96,8% пациентов, хроническая сердечная недостаточность у 72,6%, ишемическая болезнь сердца у 51,6%, тиреотоксикоз у 6,5%, синдром слабости синусового узла у 4,8% больных, 19,4% пациентов – без структурного поражения сердца. При тяжелой степени апноэ чаще встречалась постоянная форма ФП (p=0,008), а при легком течении СОАС – пароксизмальная (р=0,024). Установлено, что объемы левого и правого предсердий у пациентов с ФП и СОАС тяжелой степени больше, чем у пациентов с апноэ легкой степени. Заключение. ФП при СОАС часто встречается у пациентов без органических заболеваний сердца. Наиболее часто встречающимися факторами риска ФП у пациентов с СОАС являлись артериальная гипертензия, установленная у 96,8% обследуемых, а также ожирение (у 74,2%). Встречаемость ФП у больных с тяжелым апноэ выше, чем у пациентов с апноэ легкой степени. Постоянная форма ФП выявляется чаще, объемы предсердий больше у пациентов с СОАС тяжелой степени по сравнению с больными с легкими нарушениями дыхания во сне.</p></abstract><trans-abstract xml:lang="en"><p>Objective – to study the incidence and risk factors of atrial fibrillation (AF) in patients with obstructive sleep apnea syndrome (OSA), verified according to screening respiratory monitoring during sleep, performed during hospitalization in a therapeutic hospital. Design and methods. The study performed a retrospective analysis of 291 case histories of patients hospitalized in a therapeutic clinic in 2021-2022. All patients underwent overnight respiratory monitoring as part of the initial screening examination for sleep-disordered breathing. Results. Obstructive sleep apnea syndrome was identified in 216 patients, mild severity – in 27,8%, moderate severity – in 20,3%, severe severity – in 26,1% of patients. The incidence of atrial fibrillation in patients with diagnosed OSA was 28,7% and was significantly higher in patients with severe apnea compared to patients with mild apnea (p=0,043). According to the results of the analysis of the reasons underlying the development of AF in patients with verified apnea, arterial hypertension was identified in 96,8% of patients, chronic heart failure in 72,6%, coronary heart disease in 51,6%, thyrotoxicosis in 6,5%, sick sinus syndrome in 4,8% of patients, 19,4% of patients without structural heart damage. In severe apnea, the permanent form of AF was more common (p=0,008), and in mild OSA, paroxysmal AF was more common (p=0,024). It was found that the volumes of the left and right atria in patients with AF and severe OSA are greater than in patients with mild apnea. Conclusion. AF in OSA often occurs in patients without organic heart disease. The most common risk factors for AF in patients with OSA were arterial hypertension, found in 96,8% of subjects, as well as obesity (in 74,2%). The incidence of AF in patients with severe apnea is higher than in patients with mild apnea. The permanent form of AF is detected more often, and atrial volumes are larger in patients with severe OSA compared to patients with mild sleep-disordered breathing.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>нарушения дыхания во сне</kwd><kwd>обструктивное апноэ</kwd><kwd>ночное респираторное мониторирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>breathing disorders during sleep</kwd><kwd>obstructive apnea</kwd><kwd>night respiratory monitoring</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы выражают признательность руководителям и сотрудникам отделения респираторной терапии и кафедры функциональной диагностики ФГБОУ ВО ПСПбГМУ им. акад. И. П. Павлова Минздрава России за оказанную помощь при подготовке материалов для написания статьи. Исследование выполнено при финансовой поддержке гранта Российского научного фонда, регистрационный № НИОКТР 123022700073–7.</funding-statement><funding-statement xml:lang="en">The authors express their gratitude to the heads and staff of the Department of Respiratory Therapy and the Department of Functional Diagnostics of the Pavlov University for assistance in preparing materials for writing the article. The work was carried out with the support of the grant of the Russian Science Foundation, registration No. NIOKTR 123022700073–7.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lau DH, Linz D, Sanders P. New findings in atrial fibrillation mechanisms. Card Electrophysiol. 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