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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2025-2520</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-2520</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Риск формирования артериальной гипертензии у мальчиков-подростков с ожирением в зависимости от стадии полового созревания</article-title><trans-title-group xml:lang="en"><trans-title>Puberty associated hypertension risk evaluation in obese male adolescents</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4449-2786</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кельмансон</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kelmanson</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, профеcсор кафедры детских болезней с клиникой лечебного факультета Института медицинского образования ФГБУ «Национальный медицинский исследовательский центр им. В.А.Алмазова» МЗ РФ</p></bio><email xlink:type="simple">iakelmanson@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0740-2646</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вторникова</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vtornikova</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры детских болезней с клиникой лечебного факультета Института медицинского образования ФГБУ «Национальный медицинский исследовательский центр им. В.А.Алмазова» МЗ РФ</p></bio><email xlink:type="simple">natali28051995@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4013-0785</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.. профессор, заведующая кафедрой детских болезней с клиникой лечебного факультета Института медицинского образования ФГБУ «Национальный медицинский исследовательский центр им. В.А.Алмазова» МЗ РФ</p></bio><email xlink:type="simple">nikitina0901@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр им. В.А.Алмазова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution "Almazov National Medical Research Centre" of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2025</year></pub-date><volume>31</volume><issue>3</issue><fpage>251</fpage><lpage>264</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кельмансон И.А., Вторникова Н.И., Никитина И.Л., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Кельмансон И.А., Вторникова Н.И., Никитина И.Л.</copyright-holder><copyright-holder xml:lang="en">Kelmanson I.A., Vtornikova N.I., Nikitina I.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/2520">https://htn.almazovcentre.ru/jour/article/view/2520</self-uri><abstract><sec><title>Введение</title><p>Введение. Ожирение у детей и подростков является доказанным фактором риска формирования ближайших и отсроченных по времени нарушений со стороны сердечно-сосудистой системы.  Артериальная гипертензия (АГ) является одной из наиболее значимых коморбидностей при ожирении. Отмечается, что риск развития АГ на фоне ожирения модифицируется влиянием ряда факторов, однако влияние стадии полового созревания на риск АГ у мальчиков-подростков с ожирением изучено недостаточно.</p></sec><sec><title> Цель исследования</title><p> Цель исследования. Изучить связь риска АГ у мальчиков-подростков с ожирением с показателями полового созревания.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследовано 147 мальчиков-подростков в возрасте от 14 до 17 лет включительно с конституционально-экзогенным ожирением (код Е66.0, МКБ-10). Проводилось изучение наследственного анамнеза, анамнеза жизни, клиническое обследование по стандартным протоколам. Антропометрическое обследование включало в себя измерение роста, массы тела, расчет показателя индекса массы тела (ИМТ) по формуле [масса (кг)/рост (м2)]. ИМТ оценивался по стандартизированным перцентильным таблицам (Всемирная организация здравоохранения, 2007 г.), а также таблицам Z-score с оценкой стандартного отклонения SDS. Лабораторное исследование включало определение уровня тестостерона в плазме крови. Инструментальное исследование включало суточное мониторирование артериального давления. Диагноз АГ устанавливался в соответствии с принятыми критериями. Статистическая обработка включала в себя применение методов описательной и аналитической статистики.</p></sec><sec><title>Результаты</title><p>Результаты. Отношение шансов наличия АГ на фоне ожирения повышается с ростом значения z-скора ИМТ, стадии полового развития по шкале Таннера и уровня тестостерона плазмы.</p></sec><sec><title>Выводы</title><p>Выводы: максимальный риск АГ имеют мальчики-подростки с морбидным ожирением, оценкой полового развития по шкале Таннера 4-5 и более высоким уровнем тестостерона.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Childhood obesity is a vindicated risk factor both for early and late cardiovascular outcomes. Hypertension is one of the most significant comorbidities accompanying obesity. The risk of developing hypertension in obese patients is influenced by a variety of factors. There is a lack of knowledge in hypertension risk associated with puberty evaluation in obese adolescent boys.</p></sec><sec><title>Objective</title><p>Objective. The study was aimed to evaluate the risk of hypertension as a common comorbidity in obese adolescent boys regarding puberty.</p></sec><sec><title>Design and methods</title><p>Design and methods. The study involved 147 boys with obesity (code E66.0, ICD-10) aged 14-17 years old. Routine clinical examination was performed according to national standards. Family history and medical history data was collected. Anthropometrics were performed including weight and height measurement, body mass index calculation and evaluation using WHO tables and z-score. Laboratory study included blood testosterone levels determination. Instrumental study included 24-hour blood pressure monitoring. Hypertension diagnosis was defined using common criteria. Statistical analysis included use of descriptive and analytical methods.</p></sec><sec><title>Results</title><p>Results. Odds ratio for having hypertension during obesity are associated with higher z-BMI score, Tanner puberty score and blood testosterone level.</p></sec><sec><title>Conclusions</title><p>Conclusions. We concluded that morbid obese boys in late adolescent age, having higher Tanner puberty score, higher zBMI score and higher blood testosterone show highest odds for having hypertension.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>риск</kwd><kwd>коморбидность</kwd><kwd>ожирение</kwd><kwd>тестостерон</kwd><kwd>подростки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypertension</kwd><kwd>risk</kwd><kwd>comorbidity</kwd><kwd>obesity</kwd><kwd>testosterone</kwd><kwd>adolescents</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bixby H., Mishra A., Martinez A. R. 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