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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2015-21-3-276-285</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-257</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Гендерные различия в риске развития артериальной гипертензии у населения с высоким уровнем личностной тревожности в Р оссии/Сибири (программа ВОЗ «MONIC A- психосоциальная»)</article-title><trans-title-group xml:lang="en"><trans-title>Gender differences of hypertension risk in population with the high level of personal anxiety in Russia/Siberia (WHO program «MONIC A-psychosocial)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, руководитель межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний (ССЗ), лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Новосибирск</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Professor, Head, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Head, Laboratory of Psychological and Sociological Issues of Internal Diseases, Research Institute of Internal and Preventive Medicine, Novosibirsk</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, ведущий научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Межведомственной лаборатории эпидемиологии ССЗ, Новосибирск</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, Leading Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases, Research Institute of Internal and Preventive Medicine, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Межведомственной лаборатории эпидемиологии ССЗ, Новосибирск</p></bio><bio xml:lang="en"><p>MD, PhD, Senior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases, Research Institute of Internal and Preventive Medicine, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Межведомственной лаборатории эпидемиологии ССЗ, Новосибирск</p></bio><bio xml:lang="en"><p>PhD, senior research scientist of Laboratory of Psychological and Sociological Issues of Internal Diseases at Research Institute of Internal and Preventive Medicine, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Межведомственной лаборатории эпидемиологии ССЗ, Новосибирск</p></bio><bio xml:lang="en"><p>MD, PhD, Senior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases, Research Institute of Internal and Preventive Medicine, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Есипенко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Esipenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний НИИ терапии и профилактической медицины, Межведомственной лаборатории эпидемиологии ССЗ, Новосибирск</p></bio><bio xml:lang="en"><p>MD, Junior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases, Research Institute of Internal and Preventive Medicine, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины, Новосибирск, Россия ул. Б. Богаткова, д. 175/1, 630089. Тел./факс: +7 (383)373–10–81&#13;
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Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеваний, Новосибирск, Россия<country>Россия</country></aff><aff xml:lang="en">Research Institute of Internal and Preventive Medicine, Novosibirsk, Russia 175/1 B. Bogatkova street, 630089 Tel./Fax: +7(383)373–10–81&#13;
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Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk, Russia<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научно-исследовательский институт терапии и профилактической медицины, Новосибирск, Россия ул. Б. Богаткова, д. 175/1, 630089. Тел./факс: +7 (383)373–10–81<country>Россия</country></aff><aff xml:lang="en">Research Institute of Internal and Preventive Medicine, Novosibirsk, Russia 175/1 B. Bogatkova street, 630089 Tel./Fax: +7(383)373–10–81<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2015</year></pub-date><volume>21</volume><issue>3</issue><fpage>276</fpage><lpage>285</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О., Есипенко О.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О., Есипенко О.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Gromova E.A., Gagulin I.V., Gafarova A.V., Panov D.O., Esipenko O.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/257">https://htn.almazovcentre.ru/jour/article/view/257</self-uri><abstract><p>Цель исследования — определить гендерные различия влияния личностной тревожности (ЛТ) на риск развития (РР) артериальной гипертензии (АГ) в открытой популяции 25–64 лет в России/Сибири.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В рамках III скрининга программы ВОЗ «MONICA-psychosocial» обследована случайная репрезентативная выборка населения обоего пола 25–64 лет Новосибирска в 1994 году (мужчины: n = 657, 44,3 ± 0,4 года, отклик — 82,1 %; женщины: n = 689, 45,4 ± 0,4 года, отклик — 72,5 %). Программа скринирующего обследования включала регистрацию социально-демографических данных, определение ЛТ (тест Spielberger C. D., 1972). За 16‑летний период было выявлено 229 впервые возникших случаев АГ у женщин и 46 случаев — у мужчин.</p></sec><sec><title>Результаты</title><p>Результаты. В открытой популяции 25–64 лет высокий уровень тревожности (ВУТ) определялся у 59,9 % женщин и 50,9 % мужчин. Через 5 лет РР АГ в возрастной группе 25–64 лет был выше у мужчин (РР = 5), чем у женщин (РР = 2,3) при наличии ВУТ. Такая же динамика наблюдалась через 10 лет. Но при рассмотрении по возрастным группам в течение 10‑летнего периода у женщин 55–64 лет с ВУТ отмечен более высокий РР АГ (в 10 раз), чем у мужчин (7,9 раз). Многофакторный регрессионный анализ Кокса выявил у женщин наибольшее влияние ВУТ на риск АГ в возрасте 55–64 лет (РР = 7,9); среди мужчин влияние ВУТ на риск АГ было выше у разведенных (РР = 4,3) и овдовевших (РР = 4,8) и в возрасте 55–64 лет (РР = 5,5).</p></sec><sec><title>Заключение</title><p>Заключение. Установлена бóльшая распространенность высоких уровней ЛТ среди женщин. В то же время РР АГ выше у мужчин с ВУТ, чем у сопоставимых женщин в возрасте 25–64 лет, за исключением старших возрастных групп.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To determine the gender differences influence of personal anxiety (PA) in the risk of hypertension development in the open population aged 25–64 years old in Russia/Siberia. </p></sec><sec><title>Design and methods</title><p>Design and methods. As part of the G program III WHO “MONICA-psychosocial” a random representative sample including both sexes aged 25–64 years old was surveyed in Novosibirsk in 1994 (males: n = 657 44,3 ± 0,4 years, response — 82,1 %; women: n = 689, 45,4 ± 0,4 years, response — 72,5 %). The survey included registration of socio-demographic data, and assessment of PA (test Spielberger CD, 1972). During 16‑year follow-up 229 cases of new-onset hypertension (HTN) among women and 46 cases among men were identified.</p></sec><sec><title>Results</title><p>Results. In an open population of 25–64 high level of anxiety (HLA) was detected in 59,9 % of women and 50,9 % men. After 5 years, in population aged 25–64 years old the hazard risk (HR) of HTN development was higher in men (HR = 5) than in women (HR = 2,3) in the presence of HLA; the same results were found in 10 years. However, when considering subgroups, women aged 55–64 years old with HLA had higher HTN risk (10‑fold) than men (7,9‑fold) in 10 years. Multivariate Cox regression analysis showed that HLA had the greatest impact on the risk of HTN in female population aged 55–64 years old (HR = 7,9); among men, HLA is associated with the higher HTN risk in divorced (HR = 4,3) and widowed (HR = 4,8) subjects, and in males aged 55–64 years old (HR = 5,5).</p></sec><sec><title>Conclusion</title><p>Conclusion. We found greater prevalence of HLA traits in women compared to men. At the same time the risk of HTN is higher in men with HLA than in women aged 25–64 years, except for the older age groups. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гендерные особенности</kwd><kwd>личностная тревожность</kwd><kwd>популяция</kwd><kwd>артериальная гипертензия</kwd><kwd>риск развития</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gender differences</kwd><kwd>personal anxiety</kwd><kwd>population</kwd><kwd>arterial hypertension</kwd><kwd>hazard ratio</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бритов А. Н., Быстрова М. М. Стресс-индуцированная АГ. Профилактика заболеваний и укрепления здоровья. 2003;5:34–40. [Britov AN, Bystrova MM. Stress-induced hypertension. Disease prevention and health promotion. 2003;5:34–40. In Russian].</mixed-citation><mixed-citation xml:lang="en">Бритов А. Н., Быстрова М. М. Стресс-индуцированная АГ. 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