arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2016-22-1-61-72arthyper-285Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESГендерные особенности риска развития артериальной гипертензии у населения с депрессией в России/Сибири (программа ВОЗ «MONICA-psychosocial»)Gender-related differences of hypertension risk in population with depression in Russia/Siberia (WHO program «MONICA-psychosocial»)ГафаровВ. В.GafarovV. V.

доктор медицинских наук, профессор, руководитель межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний, лаборатории психологических и социологических проблем терапевтических заболеваний,

ул. Б. Богаткова, д. 175/1, Новосибирск, 630089

MD, PhD, DSc, Professor, Head, Collaborative Laboratory of Cardiovascular Diseases Epidemiology, Head, Laboratory of Psychological and Sociological Issues of Internal Diseases,

175/1 B. Bogatkov street, Novosibirsk, 630089

valery.gafarov@gmail.comГромоваЕ. А.GromovaE. A.

доктор медицинских наук, ведущий научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний

MD, PhD, DSc, Leading Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases,

valery.gafarov@gmail.comГагулинИ. В.GagulinI. V.

старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний

MD, Senior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases

valery.gafarov@gmail.comГафароваА. В.GafarovaA. V.

дкандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний

MD, PhD, Senior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases

valery.gafarov@gmail.comПановД. О.PanovD. O.

кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний

MD, PhD, Senior Researcher, Laboratory of Psychological and Sociological Issues of Internal Diseases

valery.gafarov@gmail.comФедеральное государственное бюджетное научное учреждение «Научно-исследовательский институт терапии и профилактической медицины»; Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеванийРоссияResearch Institute of Internal and Preventive Medicine; Collaborative Laboratory of Cardiovascular Diseases EpidemiologyRussian Federation2016040520162216172Copyright © Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О., 20162016Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О.Gafarov V.V., Gromova E.A., Gagulin I.V., Gafarova A.V., Panov D.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/285

Цель исследования — определить гендерные различия влияния депрессии на риск развития артериальной гипертензии (АГ) в открытой популяции 25–64 лет в России/Сибири.

Материалы и методы

Материалы и методы. В рамках III скрининга программы ВОЗ «MONICA-psychosocial» обследована случайная репрезентативная выборка населения Новосибирска (обоего пола, 25–64 лет) в 1994 году (мужчины: n = 657, 44,3 ± 0,4 года, отклик — 82,1%; женщины: n = 689, 45,4 ± 0,4 года, отклик — 72,5%). Программа скринирующего обследования включала: регистрацию социально-демографических данных, диагностику депрессии. За 16‑летний период было выявлено 229 впервые возникших случаев АГ у женщин и 46 случаев — у мужчин.

Результаты

Результаты. В открытой популяции 25–64 лет уровень депрессии был выше у женщин — 54,5%, чем у мужчин — 29%. Социальный градиент у лиц с депрессией по семейному положению гендерно не различался; женщины с высоким уровнем образования превалируют над мужчинами; среди мужчин больше руководителей и лиц тяжелого физического труда, среди женщин — инженерно-технических работников и лиц легкого физического труда. Риск развития АГ через 5, 10, 16 лет был выше у мужчин с депрессией, чем у женщин соответственно.

Заключение

Заключение. Депрессия в большей степени распространена у женщин, чем у мужчин; в то же время относительный риск АГ при депрессии у мужчин значительно выше, чем у женщин.

Objective

Objective. To determine the gender-related differences of depression impact on the risk (HR — hazard ratio) of hypertension (HTN) development in the general population of 25–64 years old in Russia/Siberia.

Design and methods

Design and methods. Within the III screening WHO program «MONICA-psychosocial», a random representative sample (both genders, aged 25–64 years old) of Novosibirsk citizens was formed in 1994 (men: n = 657, 44,3 ± 0,4 years, response — 82,1%; women: n = 689, 45,4 ± 0,4 years, response — 72,5%). The examination included registration of social and demographic data, diagnostics of depression. During 16‑year follow-up new-onset HTN was diagnosed in 229 women and in 46 men.

Results

Results. In an open population of 25–64 years, depression rate was higher in women (54,5%) compared to men (29%). There were no gender differences in social gradient in depressive subjects divided by marital status: women with high levels of education prevailed over men; depressive men more frequently were leaders and workers of heavy physical labor, while women mostly were engineers and workers of light physical labor. Hazard ration of HTN at 5, 10, 16 years was higher in depressive men compared to women.

Conclusions

Conclusions. Depression is more common in women than in men, however, HR is significantly higher in men than in women.

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The authors declare that there are no conflicts of interest present.