arthyperАртериальная гипертензия"Arterial’naya Gipertenziya" ("Arterial Hypertension")1607-419X2411-8524Antihypertensive League10.18705/1607-419X-2017-23-1-69-73arthyper-552Research ArticleСтатьиArticlesСУБКЛИНИЧЕСКИЙ МУЛЬТИФОКАЛЬНЫЙ АТЕРОСКЛЕРОЗ: КАК ЕГО ВЫЯВЛЯТЬ И НАДО ЛИ?SUBCLINICAL MULTIFOCAL ATHEROSCLEROSIS: SHOULD IT BE DETECTED?СуминА. Н.SuminA. N.

Сумин Алексей Николаевич — доктор медицинских наук, заведующий отделом мультифокального атеросклероза.

Сосновый бул., д. 6, г. Кемерово, Россия, 650002. Тел.: +7(3842)64–44–61

Alexei N. Sumin - Doctor of Medical Sciences, Chief of Department of Multifocal Atherosclerosis.

6 Sosnoviy boulevard, Kemerovo, 650002. Phone: +7(3842)64–44–61

an_sumin@mail.ruНаучно-исследовательский институт комплексных проблем сердечно-сосудистых заболеванийРоссияResearch Institute for Complex Issues of Cardiovascular DiseasesRussian Federation2017060320172316973Copyright © Сумин А.Н., 20172017Сумин А.Н.Sumin A.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://htn.almazovcentre.ru/jour/article/view/552

В настоящей статье обсуждается клиническая и прогностическая значимость наличия мультифокального атеросклероза, то есть сочетанного атеросклеротического поражения нескольких артериальных бассейнов. Также рассматриваются вопросы диагностики субклинических форм мультифокального атеросклероза.

The paper discusses the clinical and prognostic role of multifocal atherosclerosis, namely co-existent atherosclerotic lesions of several arteries. In addition, the issues of the diagnosis of subclinical multifocal atherosclerosis are reviewed.

мультифокальный атеросклерозсубклинический атеросклероздиагностикаmultifocal atherosclerosissubclinical atherosclerosisdiagnosticsReferencesSuárez C, Zeymer U, Limbourg T, Baumgartner I, Cacoub P, Poldermans D. REACH Registry Investigators. Influence of polyvascular disease on cardiovascular event rates. Insights from the REACH Registry. Vasc Med. 2010;15(4):259–65. doi: 10.1177/1358863X10373299.Suárez C, Zeymer U, Limbourg T, Baumgartner I, Cacoub P, Poldermans D. REACH Registry Investigators. Influence of polyvascular disease on cardiovascular event rates. Insights from the REACH Registry. Vasc Med. 2010;15(4):259–65. doi: 10.1177/1358863X10373299.Gallino A, Aboyans V, Diehm C, Cosentino F, Stricker H, Falk E et al. European Society of Cardiology Working Group on peripheral circulation. Non-coronary atherosclerosis. Eur Heart J. 2014;35(17):1112–9. doi: 10.1093/eurheartj/ehu071.Gallino A, Aboyans V, Diehm C, Cosentino F, Stricker H, Falk E et al. European Society of Cardiology Working Group on peripheral circulation. Non-coronary atherosclerosis. Eur Heart J. 2014;35(17):1112–9. doi: 10.1093/eurheartj/ehu071.van der Meer MG, Cramer MJ, van der Graaf Y, Appelman Y, Doevendans PA, Nathoe HM. SMART Study Group. The impact of polyvascular disease on long-term outcome in percutaneous coronary intervention patients. Eur J Clin Invest. 2014;44(3):231–9. doi: 10.1111/eci.12222.van der Meer MG, Cramer MJ, van der Graaf Y, Appelman Y, Doevendans PA, Nathoe HM. SMART Study Group. The impact of polyvascular disease on long-term outcome in percutaneous coronary intervention patients. Eur J Clin Invest. 2014;44(3):231–9. doi: 10.1111/eci.12222.Барбараш Л. С., Сумин А. Н. Диагностика ИБС перед операциями на некоронарных сосудистых бассейнах. Ангиология и сосудистая хирургия. 2016;22(2):188–196. [Barbarash LS, Sumin AN. Diagnosis of coronary artery disease prior to operations on noncoronary arterial basins. Angiologiya i Sosudistaya Khirurgiya = Angiology and Vascular Surgery. 2016;22 (2):188–96. In Russian].Барбараш Л. С., Сумин А. Н. Диагностика ИБС перед операциями на некоронарных сосудистых бассейнах. Ангиология и сосудистая хирургия. 2016;22(2):188–196. [Barbarash LS, Sumin AN. Diagnosis of coronary artery disease prior to operations on noncoronary arterial basins. Angiologiya i Sosudistaya Khirurgiya = Angiology and Vascular Surgery. 2016;22 (2):188–96. In Russian].Найден Т. В., Бартош-Зеленая С. Ю., Плавинский С. Л., Евсикова И. А. Предикторы изолированных и сочетанных атеросклеротических поражений на субклинической стадии у мужчин среднего возраста и их взаимосвязь с метаболическим синдромом. Артериальная гипертензия. 2017; 23(1):56–68. [Nayden TV, Bartosh-Zelenaya SYu, Plavinskij SL, Evsikova IA. Predictors of isolated and combined atherosclerotic lesions on subclinical stage in middle-aged men and its correlation with metabolic syndrome. Arterial’naya Gipertenziya = Arterial Hypertension. 2017;23(1):56–68. In Russian].Найден Т. В., Бартош-Зеленая С. Ю., Плавинский С. Л., Евсикова И. А. Предикторы изолированных и сочетанных атеросклеротических поражений на субклинической стадии у мужчин среднего возраста и их взаимосвязь с метаболическим синдромом. Артериальная гипертензия. 2017; 23(1):56–68. [Nayden TV, Bartosh-Zelenaya SYu, Plavinskij SL, Evsikova IA. Predictors of isolated and combined atherosclerotic lesions on subclinical stage in middle-aged men and its correlation with metabolic syndrome. Arterial’naya Gipertenziya = Arterial Hypertension. 2017;23(1):56–68. In Russian].McCully KS. Homocysteine and the pathogenesis of atherosclerosis. Expert Rev Clin Pharmacol. 2015;8(2):211–9. doi: 10.1586/17512433.2015.1010516.McCully KS. Homocysteine and the pathogenesis of atherosclerosis. Expert Rev Clin Pharmacol. 2015;8(2):211–9. doi: 10.1586/17512433.2015.1010516.Tanaka S, Kaneko H, Kano H, Matsuno S, Suzuki S, Takai H et al. The predictive value of the borderline anklebrachial index for long-term clinical outcomes: an observational cohort study. Atherosclerosis. 2016;250:69–76. doi: 10.1016/j. atherosclerosis.2016.05.014.Tanaka S, Kaneko H, Kano H, Matsuno S, Suzuki S, Takai H et al. The predictive value of the borderline anklebrachial index for long-term clinical outcomes: an observational cohort study. Atherosclerosis. 2016;250:69–76. doi: 10.1016/j. atherosclerosis.2016.05.014.Cecere A, Riccioni G, Sforza N, Marano R, Guglielmi G. Coronary artery calcium score and coronary computed tomography angiography for patients with asymptomatic polyvascular (non-coronary) atherosclerosis. Singapore Med J. 2016. doi: 10.11622/smedj.2016186. [Epub ahead of print].Cecere A, Riccioni G, Sforza N, Marano R, Guglielmi G. Coronary artery calcium score and coronary computed tomography angiography for patients with asymptomatic polyvascular (non-coronary) atherosclerosis. Singapore Med J. 2016. doi: 10.11622/smedj.2016186. [Epub ahead of print].Корок Е. В., Сумин А. Н., Синьков М. А., Нагирняк О. А., Чичкова Т. Ю., Барбараш Л. С. Частота выявления интактных коронарных артерий в зависимости от показаний для плановой коронарной ангиографии. Российский кардиологический журнал. 2016;2(130):52–59. DOI: http://dx.doi. org/10.15829/1560–4071–2016–2-52–59 [Korok EV, Sumin AN, Sinkov MA, Nagirnyak OA, Chichkova TYu, Barbarash LA. The prevalence of intact coronary arteries in relation with indications for scheduled coronary arteriography. Russian Journal of Cardiology. 2016;2(130):52–59. doi: http://dx.doi.org/10.15829/1560–4071–2016–2-52–59. In Russian].Корок Е. В., Сумин А. Н., Синьков М. А., Нагирняк О. А., Чичкова Т. Ю., Барбараш Л. С. Частота выявления интактных коронарных артерий в зависимости от показаний для плановой коронарной ангиографии. Российский кардиологический журнал. 2016;2(130):52–59. DOI: http://dx.doi. org/10.15829/1560–4071–2016–2-52–59 [Korok EV, Sumin AN, Sinkov MA, Nagirnyak OA, Chichkova TYu, Barbarash LA. The prevalence of intact coronary arteries in relation with indications for scheduled coronary arteriography. Russian Journal of Cardiology. 2016;2(130):52–59. doi: http://dx.doi.org/10.15829/1560–4071–2016–2-52–59. In Russian].Patel MR, Dai D, Hernandez AF, Douglas PS, Messenger J, Garratt KN et al. Prevalence and predictors of nonobstructive coronary artery disease identified with coronary angiography in contemporary clinical practice. Am Heart J. 2014;167(6):846–852. doi:10.1016/j.ahj.2014.03.001.Patel MR, Dai D, Hernandez AF, Douglas PS, Messenger J, Garratt KN et al. Prevalence and predictors of nonobstructive coronary artery disease identified with coronary angiography in contemporary clinical practice. Am Heart J. 2014;167(6):846–852. doi:10.1016/j.ahj.2014.03.001.Task Force Members, Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C et al. 2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J. 2013;34(38):2949–3003.Task Force Members, Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C et al. 2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J. 2013;34(38):2949–3003.Smeeth L, Skinner JS, Ashcroft J, Hemingway H, Timmis A. Chest Pain Guideline Development Group. Chest Pain Guideline Development Group. NICE clinical guideline: chest pain of recent onset. Br J Gen Pract. 2010;60(577):607–10. doi: 10.3399/bjgp10X515124.Smeeth L, Skinner JS, Ashcroft J, Hemingway H, Timmis A. Chest Pain Guideline Development Group. Chest Pain Guideline Development Group. NICE clinical guideline: chest pain of recent onset. Br J Gen Pract. 2010;60(577):607–10. doi: 10.3399/bjgp10X515124.Neglia D, Rovai D, Caselli C, Pietila M, Teresinska A, Aguadé-Bruix S et al. EVINCI Study Investigators. Detection of significant coronary artery disease by non-invasive anatomical and functional imaging. Circ Cardiovas Imaging. 2015;8(3): e002179.Neglia D, Rovai D, Caselli C, Pietila M, Teresinska A, Aguadé-Bruix S et al. EVINCI Study Investigators. Detection of significant coronary artery disease by non-invasive anatomical and functional imaging. Circ Cardiovas Imaging. 2015;8(3): e002179.Lee H, Yoon YE, Park JB, Kim HL, Park HE, Lee SP et al. The incremental prognostic value of cardiac computed tomography in comparison with single-photon emission computed tomography in patients with suspected coronary artery disease. PLoS One. 2016;11(8):e0160188. doi: 10.1371/journal.pone.0160188.Lee H, Yoon YE, Park JB, Kim HL, Park HE, Lee SP et al. The incremental prognostic value of cardiac computed tomography in comparison with single-photon emission computed tomography in patients with suspected coronary artery disease. PLoS One. 2016;11(8):e0160188. doi: 10.1371/journal.pone.0160188.

The authors declare that there are no conflicts of interest present.