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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2003-9-2-37-41</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-871</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Синдром обструктивного апноэ сна -фактор риска артериальной гипертонии</article-title><trans-title-group xml:lang="en"><trans-title>Obstructive sleep apnea syndrome is a risk factor for arterial hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калинкин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalinkin</surname><given-names>A. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>83 КБ Федерального управления медико-биологических и экстремальных проблем при Минздраве РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2003</year></pub-date><volume>9</volume><issue>2</issue><fpage>37</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Калинкин А.Л., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Калинкин А.Л.</copyright-holder><copyright-holder xml:lang="en">Kalinkin A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/871">https://htn.almazovcentre.ru/jour/article/view/871</self-uri><abstract><p>Синдром обструктивного апноэ сна (COAC) является фактором риска развития сердечно-сосудистых заболеваний Результаты эпидемиологических, обсервационных и экспериментальных работ подтверждают существенную роль COAC в формировании артериальной гипертонии (AT) посредством хронической симпатической активации и нейрогуморальных изменений, инициируемых во время сна Особенно большое значение проблема COAC приобретает в развитии рефрактерной AT Лечение COAC методом СИПАП-терапии приводит не только к устранению обструктивных нарушений дыхания во время сна, но и зачастую снижает артериальное давление у больных AT и улучшает прогноз течения сердечнососудистых заболеваний</p></abstract><trans-abstract xml:lang="en"><p>The obstructive sleep apnea syndrome (OSAS) is a risk factor for cardiovascular diseases The results of epidemiological, observational, and experimental studies support the fact that OSAS is of considerable importance in the development of arterial hypertension via chronic sympathetic activation and sleep-induced neurohumoral changes OSAS is of prime importance in the development of refractory AH CPAP therapy not only eliminates sleep-induced obstructive respiratory impairments, but frequently lowers blood pressure in hypertensive patients, and improves the prognosis of cardiovascular diseases</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>синдром обструктивного апноэ сна</kwd><kwd>обструктивные нарушения дыхания во время сна</kwd><kwd>рефрактерная артериальная гипертония</kwd><kwd>СИПАП-терапия</kwd><kwd>лечение артериальной гипертонии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>obstructive sleep apnea syndrome</kwd><kwd>sleep-induced obstructive respiratory impairment</kwd><kwd>CPAP therapy</kwd><kwd>treatment of arterial hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Young Т, Palta М, Dempsey J et al. 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