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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2003-9-2-67-70</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-878</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Артериальная гипертензия и сахарный диабет типа 2 у больных метаболическим синдромом: особенности влияния на липидный спектр</article-title><trans-title-group xml:lang="en"><trans-title>Arterial hypertension and type 2 diabetes mellitus in patients with metabolic disorders: Their impact on the lipid spectrum</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чередникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Cherednikova</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камерер</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamerer</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Уральская государственная медицинская академия дополнительного образования Минздрава РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2003</year></pub-date><volume>9</volume><issue>2</issue><fpage>67</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузин А.И., Чередникова М.А., Васильев А.А., Камерер О.В., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Кузин А.И., Чередникова М.А., Васильев А.А., Камерер О.В.</copyright-holder><copyright-holder xml:lang="en">Kuzin A.I., Cherednikova M.A., Vasilyev A.A., Kamerer O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/878">https://htn.almazovcentre.ru/jour/article/view/878</self-uri><abstract><p>Цель работы - изучение особенностей липидного спектра у больных метаболическим синдромом при наличии и отсутствии артериальной гипертензии (AT) и сахарного диабета (СД) типа 2 В исследование включено 176 больных метаболическим синдромом, у 138 больных диагностирована АГ, из них у 39 человек - СД типа 2 Клинико-лабораторное обследование включало определение индекса массы тела, отношения объем талии/объем бедер, определение показателей липидного спектра Все пациенты были разделены на 3 группы 1-я группа - 38 человек без АГ и СД типа 2, 2-я - 99 человек с изолированной АГ без СД типа 2, 3-я - 39 человек с АГ и СД типа 2 Нарастание выраженности абдоминального ожирения ассоциировалось с усилением атерогенности дислипидемии Развитие АГ в рамках метаболического синдрома сопровождалось повышением уровня общего холестерина, что можно рассматривать как усиление эндотелиальной дисфункции Присоединение СД типа 2 сопровождалось трансформированием метаболической дислипидемии в диабетическую По результатам исследования предложен новый показатель, характеризующий атерогенность дислипидемии у больных метаболическим синдромом</p></abstract><trans-abstract xml:lang="en"><p>The study was undertaken to examine the specific features of the lipid spectrum in patients with metabolic disorders in the absence or presence of arterial hypertension (AH) and type 2 diabetes mellitus (DM) The study covered 176 patients with metabolic disorders, 138 patients were diagnosed as having AH, of them 39 patients had type 2 DM Clinical and laboratory studies involved the estimation of the body mass index, waist/hip ratio, and lipid spectrum All the patients were divided into 3 groups I) 38 without AH and type 2 DM, 2) 99 with isolated AH without type 2 DM, 3) 39 with AH and type 2 DM The higher severity of abdominal obesity was associated with enhanced dyslipidemia atherogemcity The development of AH m the presence of metabolic disorders was accompanied by higher total cholesterol levels, which may be considered as aggravated endothelial dysfunction Its concurrence with type 2 DM was attended by transformation of metabolic to diabetic dyslipidemia The study has yielded a new index that characterizes dyslipidemia atherogemcity in patients with metabolic disorders</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>артериальная гипертензия</kwd><kwd>сахарный диабет</kwd><kwd>дислипидемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic disorders</kwd><kwd>arterial hypertension</kwd><kwd>diabetes mellitus</kwd><kwd>dyslipidemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen F General characteristics of the insulin resistance syndrome preva lence and hentability European Group for the study of Insulin Resistance (EGlR) Drugs 1999,58 (suppl I) 7-10</mixed-citation><mixed-citation xml:lang="en">Nielsen F General characteristics of the insulin resistance syndrome preva lence and hentability European Group for the study of Insulin Resistance (EGlR) Drugs 1999,58 (suppl I) 7-10</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Donahue RP, Orchard J Hypennsulmemia and insulin resistense associations with cardiovascular nsk factors and disease Cardiovasc Risk Factors 1993, 1 12-8</mixed-citation><mixed-citation xml:lang="en">Donahue RP, Orchard J Hypennsulmemia and insulin resistense associations with cardiovascular nsk factors and disease Cardiovasc Risk Factors 1993, 1 12-8</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Haffner SM Obesity and the metabolic syndrome the SanAntomo Hean Study Br J Nutr 2000, 83 (suppl I) 67-70</mixed-citation><mixed-citation xml:lang="en">Haffner SM Obesity and the metabolic syndrome the SanAntomo Hean Study Br J Nutr 2000, 83 (suppl I) 67-70</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Steiner G, Lewis G Hypennsulmemia and tnglycende-nch lipoproteins Diabetes 1996, 45 (suppl 3) 24-6</mixed-citation><mixed-citation xml:lang="en">Steiner G, Lewis G Hypennsulmemia and tnglycende-nch lipoproteins Diabetes 1996, 45 (suppl 3) 24-6</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Петрова T.B., Стрюк Р.И. u дp. О взаимосвязи избыточной массы тела, артериальной гипертонии, гиперинсулинемии и нарушения толерантности к глюкозе Кардиология 2001, 30-3</mixed-citation><mixed-citation xml:lang="en">Петрова T.B., Стрюк Р.И. u дp. О взаимосвязи избыточной массы тела, артериальной гипертонии, гиперинсулинемии и нарушения толерантности к глюкозе Кардиология 2001, 30-3</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Howard BV Pathogenesis of diabetic dyslipidaemia Diabetes Rev 1995, 3 423-32</mixed-citation><mixed-citation xml:lang="en">Howard BV Pathogenesis of diabetic dyslipidaemia Diabetes Rev 1995, 3 423-32</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Laakso M Epidemiology of diabetic dyslipidemta Diabetes Rev 1995,3 408-22</mixed-citation><mixed-citation xml:lang="en">Laakso M Epidemiology of diabetic dyslipidemta Diabetes Rev 1995,3 408-22</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
