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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">arthyper</journal-id><journal-title-group><journal-title xml:lang="ru">Артериальная гипертензия</journal-title><trans-title-group xml:lang="en"><trans-title>"Arterial’naya Gipertenziya" ("Arterial Hypertension")</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-419X</issn><issn pub-type="epub">2411-8524</issn><publisher><publisher-name>Antihypertensive League</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/1607-419X-2004-10-3-158-160</article-id><article-id custom-type="elpub" pub-id-type="custom">arthyper-933</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Роль жизненного истощения в развитии артериальной гипертензии у мужчин 25-64 лет (эпидемиологическое исследование на основе программы ВОЗ ”MONICA”)</article-title><trans-title-group xml:lang="en"><trans-title>The role of life exhaustion in the development of arterial hypertension in 25-64-year-old men: Epidemiological survey based on the WHO program "MONICA"</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>Ye. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ терапии СО РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Internal Medicine SB RAMS</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-2"><institution>НИИ терапии СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2004</year></pub-date><volume>10</volume><issue>3</issue><fpage>158</fpage><lpage>160</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Gromova Y.A., Gagulin I.V., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://htn.almazovcentre.ru/jour/article/view/933">https://htn.almazovcentre.ru/jour/article/view/933</self-uri><abstract><p>Цель исследования. Изучение влияния жизненного истощения на риск возникновения артериальной гипертензии (АГ) у мужчин в возрасте 25-64 лет в течение 6 лет. Материалы и методы. В рамках программы ВОЗ "MONICA -психосоциальная" было проведено скринирующее исследование населения в 1994 г. Обследована случайная репрезентативная выборка мужчин (657 человек) в возрасте 25-64 лет, жителей одного из районов Новосибирска. Показатель откликов был 82,1 %. Период наблюдения составил 6 лет (1994—2000 гг.). Статистический анализ проводили с помощью пакета программ "SPSS-10". Кокс-пропорциональная регрессионная модель использована для оценки относительного риска развития АГ. Для оценки достоверности различий между группами использовали критерий x2. Результаты. В изучаемой популяции мужчин 25-64 лет, страдающих АГ, распространенность жизненного истощения высока и составляет 73,796 (средний уровень жизненного истощения 5896; высокий уровень жизненного истощения 15,796). В течение 6-летнего периода наблюдали тенденцию к увеличению риска развития АГ у мужчин с жизненным истощением в 2 раза. Относительный риск развития АГ в течение 6 лет у нормотензивных мужчин в возрасте 25-64 лет был в 2 раза выше у лиц с жизненным истощением, чем без него. Среди мужчин с жизненным истощением встречались лица как с высшим образованием и занимающие руководящие должности, так и лица с начальным уровнем образования, занимающиеся тяжелым и средним физическим трудом; пенсионеры; лица с низким уровнем социальной поддержки. Заключение. Полученные результаты позволяют рассматривать жизненное истощение как один из патогенетических механизмов, способствующих развитию АГ.</p></abstract><trans-abstract xml:lang="en"><p>Aim. To study i lie impact of life exhaustion on the risk for the development of arterial hypertension (AH) in 25-64-year-old men for 6 years. Subjects and methods. In 1994, a screening survey was performed within the framework of the WHO program "MONICA - psychosocial". A random representative sample of males (n = 657) aged 25-64 years who resided in one of the Novosibirsk districts was examined. The response rate was 82.1 %. The follow-up lasted 6 years (1904-2000). A statistical analysis was made, by using a "SPSS-10" program package. The Cox-proportional regression model was used to assess the relative risk of AH. The c_ test was applied to estimate the significance of differences between the groups. Results. In the examined population of 25-64-year-old men suffering from AH. the spread of life exhaustion is high and equal to 73-796 (mean 58 %; the high life exhaustion is 15.796): During the 6-year follow-up. there was a trend for the risk of AH to show a 2-fold increase in the exhausted males. The relative risk of AH. which was studied in normotensive males aged 25-64 years dining 6 years, was 2 times higher in the exhausted individuals than that in the unexhausted ones. Among the exhausted males, there were both persons having a higher education or holding leading posts and those having a primary education, or making hard and moderate work; pensioners, and individuals at the low social level. Conclusion. The findings suggest that life exhaustion is a pathogenetic mechanism that contributes to the development of AH.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>психосоциальный стресс</kwd><kwd>жизненное истощение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>psychosocial stress</kwd><kwd>life exhaustion</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Everson S.A., Goldberg D.E., Kaplan G.A. et al. Anger expression and incident hypertension. Psychosom Med 1998; 60: 730-5.</mixed-citation><mixed-citation xml:lang="en">Everson S.A., Goldberg D.E., Kaplan G.A. et al. Anger expression and incident hypertension. 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