Enalapril plus Indapamid in the treatment All: effect and safety estimation of rational pharmacotherapy. Design and main results of trial “EP1GRAPH-2”
https://doi.org/10.18705/1607-419X-2006-12-1-41-51
Abstract
Study EPIGRAPH-2 focuses on evaluating clinical efficacy and safety of a combination treatment for AH including the use of non-fixed combinations of enalapril and indapamid. It was shown that early initiation of treatment with the non-fixed combination of enalapril and indapamid (Enzix) in patients with I-II degree AH as compared to routine therapy results in a fast reduction of BP, significant decreases in numbers of patients with LV hypertrophy (LVH) and proteinuria, improvement of quality of life in patients with AH, decrease in the frequency of hospitalizations and additional visits to doctor's office. Furthermore this therapy is cost effective.
About the Authors
Y. .. BelenkovRussian Federation
F. .. Ageev
Russian Federation
S. .. Boizov
Russian Federation
L. .. Lascbnic
Russian Federation
V. .. Mareev
Russian Federation
R. .. Oganov
Russian Federation
L. .. Olbinskaya
Russian Federation
B. .. Obrenovich-Kirchanski
Russian Federation
M. .. Ostoich
Russian Federation
Y. .. Pozdnyakov
Russian Federation
I. .. Chazova
Russian Federation
E. .. Shlyakhto
Russian Federation
Review
For citations:
Belenkov Y..., Ageev F..., Boizov S..., Lascbnic L..., Mareev V..., Oganov R..., Olbinskaya L..., Obrenovich-Kirchanski B..., Ostoich M..., Pozdnyakov Y..., Chazova I..., Shlyakhto E... Enalapril plus Indapamid in the treatment All: effect and safety estimation of rational pharmacotherapy. Design and main results of trial “EP1GRAPH-2”. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2006;12(1):41-51. (In Russ.) https://doi.org/10.18705/1607-419X-2006-12-1-41-51
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