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Глюкозо-инсулиново-калиевая смесь при остром коронарном синдроме. Точку ставить рано

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Аннотация

Глюкозо-инсулиново-калиевая смесь (ГИКС) используется в кардиологии с 1960-х годов, но на сегодняшний день данные об эффективности подобной терапии остаются противоречивыми. В обзоре освещены механизмы кардиопротективного действия компонентов ГИКС. результаты основных экспериментальных и крупных клинических исследований. Представлены собственные данные об эффективности терапии ГИКС у пациентов с острым коронарным синдромом без подъема сегмента ST, демонстрирующие улучшение сократительной функции миокарда и антиишемическое действие, а также возможную роль взаимодействия эффектов терапии ГИКС и эндогенных механизмов кардиопротекции.

Об авторах

А. Н. Яковлев
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Россия


Е. М. Нифонтов
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Россия


Н. С. Щербак
ФГУ «Федеральный центр сердца, крови и эндокринологии имени В.А. Алмазова Росмедтехнологий»
Россия


М. М. Галагудза
ФГУ «Федеральный центр сердца, крови и эндокринологии имени В.А. Алмазова Росмедтехнологий»
Россия


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Для цитирования:


Яковлев А.Н., Нифонтов Е.М., Щербак Н.С., Галагудза М.М. Глюкозо-инсулиново-калиевая смесь при остром коронарном синдроме. Точку ставить рано. Артериальная гипертензия. 2008;14(1-S2):137-146.

For citation:


., ., ., . . "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2008;14(1-S2):137-146. (In Russ.)

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