Глюкозо-инсулиново-калиевая смесь при остром коронарном синдроме. Точку ставить рано
Аннотация
Глюкозо-инсулиново-калиевая смесь (ГИКС) используется в кардиологии с 1960-х годов, но на сегодняшний день данные об эффективности подобной терапии остаются противоречивыми. В обзоре освещены механизмы кардиопротективного действия компонентов ГИКС. результаты основных экспериментальных и крупных клинических исследований. Представлены собственные данные об эффективности терапии ГИКС у пациентов с острым коронарным синдромом без подъема сегмента ST, демонстрирующие улучшение сократительной функции миокарда и антиишемическое действие, а также возможную роль взаимодействия эффектов терапии ГИКС и эндогенных механизмов кардиопротекции.
Об авторах
А. Н. Яковлев
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Россия
Россия
Е. М. Нифонтов
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Россия
Россия
Н. С. Щербак
ФГУ «Федеральный центр сердца, крови и эндокринологии имени В.А. Алмазова Росмедтехнологий»
Россия
Россия
М. М. Галагудза
ФГУ «Федеральный центр сердца, крови и эндокринологии имени В.А. Алмазова Росмедтехнологий»
Россия
Россия
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Рецензия
Для цитирования:
Яковлев А.Н., Нифонтов Е.М., Щербак Н.С., Галагудза М.М. Глюкозо-инсулиново-калиевая смесь при остром коронарном синдроме. Точку ставить рано. Артериальная гипертензия. 2008;14(1-S2):137-146.
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