Polymorbidity in hypertensive patients
https://doi.org/10.18705/1607-419X-2019-25-2-200-208
Abstract
Background. Hypertension (HTN) is often combined with other diseases, that significantly complicate its course, worsen the prognosis, interfere with the therapeutic and preventive measures. Therefore, assessing the development and structure of polymorbidity (PM) in hypertension is a relevant issue. Objective. To study the structure and degree of PM in hypertensive patients depending on age and gender. Design and methods. We conducted an analysis of 20 560 case histories of patients with HTN and without HTN (men and women), inhabitants of West Siberia-Novosibirsk region, who underwent examination and treatment at the clinic of the Federal Research Center of Fundamental and Translational Medicine in Novosibirsk. All identified diagnoses (nosological forms and classes according to the International Classification of Diseases of the 10th revision, ICD‑10) were considered. Transnosological PM was assessed by the average number of nosologies corresponding to the three-digit ICD‑10 rubric. Results. An increase in the PM index by 16,8 % was found in HTN patients compared to patients without HTN. Among HTN patients, there was an increase in the incidence of comorbid diseases of the circulatory system (in the 16–39 age group in men — by 46 %, in women — by 42,8 %), the endocrine system, eating disorders and metabolism (in the age group 16–39 years for men — by 19,3 %, for women — by 45,2 %), the musculoskeletal system, urinary system (for men) and neoplasms (for women) compared with patients without HTN. Conclusions. We found a high rate of transnosological PM in HTN patients was found and defined its structure.
About the Authors
E. V. Sevostyanova
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
MD, PhD, Senior Researcher, Laboratory of the Pathogenesis of Somatic Diseases, Department of Medical and Environmental Studies
2 Timakova street, Novosibirsk, 630117 Russia
Yu. A. Nikolaev
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
MD, PhD, DSc, Chief Scientific Researcher, Acting Deputy Director for Scientific and Medical Work, Head, Laboratory of the Pathogenesis of Somatic Diseases, Department of Medical and Environmental Studies
2 Timakova street, Novosibirsk, 630117 Russia
I. M. Mitrofanov
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
MD, PhD DSc, Leading Researcher, Laboratory of the Pathogenesis of Somatic Diseases, Department of Medical and Environmental Studies
2 Timakova street, Novosibirsk, 630117 Russia
V. Ya. Polyakov
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
MD, PhD, DSc, Leading Researcher, Laboratory of the Pathogenesis of Somatic Diseases, Department of Medical and Environmental Studies
2 Timakova street, Novosibirsk, 630117 Russia
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Sevostyanova E.V., Nikolaev Yu.A., Mitrofanov I.M., Polyakov V.Ya. Polymorbidity in hypertensive patients. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2019;25(2):200-208. (In Russ.) https://doi.org/10.18705/1607-419X-2019-25-2-200-208
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