Orthostatic hypotension and atrial fibrillation: is there a relationship?
https://doi.org/10.18705/1607-419X-2021-27-4-409-414
Abstract
Orthostatic hypotension (OH), a possible marker of autonomic dysfunction, reflects the inability of reflex cardiovascular mechanisms to compensate for the fall in venous return in the upright position. This is a manifestation of structural and functional abnormalities of the cardiovascular system. Significance of the orthostatic hypotension is underestimated, while it is associated with all-cause mortality and cardiovascular disease. The article reviews the relationship between atrial fibrillation (AF) and OH. The pathogenetic mechanisms of OH are considered, including various subgroups, e. g. elderly patients. The article also discusses the relationship between OH, AF and cerebrovascular complications. Available evidence suggests that impaired orthostatic hemodynamic response should be considered as a new risk factor for AF. Further research is needed for better understanding of the association between AF and OH, as well as their management.
About the Authors
O. N. Antropova
Altay State Medical University
Russian Federation
Russian Federation
Oxana Nikolaevna Antropova - MD, PhD, DSc, Professor, Department of Therapy and Occupational Diseases, Altai State Medical University.
40 Lenin street, Barnaul, 656038, Tel.: 8(3852)20–12–79
I. V. Osipova
Altay State Medical University
Russian Federation
Russian Federation
Irina Vladimirovna Osipova - MD, Head, Department of Therapy and Occupational Diseases, Altai State Medical University.
40 Lenin street, Barnaul, 656038
G. G. Efremushkin
Altay State Medical University
Russian Federation
Russian Federation
German Gergievich Efremushkin - MD, PhD, DSc, Professor, Department of Therapy and Occupational Diseases, Altai State Medical University.
40 Lenin street, Barnaul, 656038
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Supplementary files
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For citations:
Antropova O.N., Osipova I.V., Efremushkin G.G. Orthostatic hypotension and atrial fibrillation: is there a relationship? "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2021;27(4):409-414. (In Russ.) https://doi.org/10.18705/1607-419X-2021-27-4-409-414
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