The relationship of epicardial adipose tissue and metabolic syndrome
https://doi.org/10.18705/1607-419X-2023-29-2-186-193
Abstract
Visceral obesity is a key link in the metabolic syndrome and can affect the development of cardiovascular diseases. Objective. The aim of the study was to identify the clinical, laboratory and instrumental characteristics of patients with coronary artery disease, to analyze adverse cardiovascular events after coronary bypass surgery, according to the thickness of the epicardial adipose tissue (EAT). Design and methods. The study included 178 patients who underwent coronary bypass surgery. The median values of the thickness of the EAT was 0,4 cm. The patients were divided into 2 groups: group 1 — epicardial fat < 0,44 cm (n = 84) and group 2 — epicardial fat > 0,44 cm (n = 94). Results. The frequency of metabolic syndrome in group 1 was 59,5 %, while in group 2 — 74,5 % (p = 0,017). The thickness of the EAT correlated with blood glucose (r = 0,28, p = 0,003), body mass index (BMI) (r = 0,27, p = 0,010), waist circumference (r = 0,26, p = 0,001). End-diastolic volume of the left ventricle (p = 0,016), stroke volume (p = 0,014), thickness of the interventricular septum (p = 0,010), mass of the left ventricular myocardium (p = 0,048), left ventricular myocardial mass index (p = 0,035) were higher in the group with a higher content of EAT. The metabolic syndrome was a significant predictor of the EAT thickness. Conclusions. The EAT thickness is associated with the metabolic syndrome and its components.
Keywords
Supporting agencies: The research was carried out with the support of the grant of the Russian Science Foundation No. 21-75-00065.
About the Authors
I. A. Mustafina
Bashkir State Medical University
Russian Federation
Russian Federation
Irina A. Mustafina - MD, PhD, Associate Professor of Propaedeutics of Internal Diseases Department, Bashkir State Medical University.
3 Lenin street, Ufa, 450008
A. A. Dolganov
Bashkir State Medical University
Russian Federation
Russian Federation
Arkady A. Dolganov - MD, Head, Vascular Surgery Department, Bashkir State Medical University Clinic.
3 Lenin street, Ufa, 450008
М. A. Kutlubaev
Bashkir State Medical University
Russian Federation
Russian Federation
Mansur A. Kutlubaev - MD, Head, Department of Neurology, Bashkir State Medical University.
3 Lenin street, Ufa, 450008
N. Sh. Zagidullin
Bashkir State Medical University
Russian Federation
Russian Federation
Naufal Sh. Zagidullin - MD, PhD, Head, Department of Propaedeutics of Internal Diseases, Bashkir State Medical University.
3 Lenin street, Ufa, 450008
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For citations:
Mustafina I.A., Dolganov A.A., Kutlubaev М.A., Zagidullin N.Sh. The relationship of epicardial adipose tissue and metabolic syndrome. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2023;29(2):186-193. (In Russ.) https://doi.org/10.18705/1607-419X-2023-29-2-186-193
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