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RESOURCE MAINTENANCE TREATMENT OF ARTERIAL HYPERTENSION IN OUTPATIENT CLINICS

https://doi.org/10.18705/1607-419X-2017-23-1-25-35

Abstract

Due to the significant financial costs associated with the management of arterial hypertension (HTN), the optimization of health care resource distribution is required.

Objective. To study the resource maintenance treatment of HTN in outpatient clinics. design and methods. The study included two stages. Firstly, we selected a sample of primary HTN patients based on the screening of primary medical records (n = 1766). Secondly, we performed a telephone survey 6 months after the inclusion (n = 1419).

Results. Outpatients are characterized by a high frequency of visits to the doctor: 2,9 physician’s counseling, 2,6 cardiologist’s counseling, 0.21 cases of medical emergencies, 0.08 hospitalizations per 1 patient for 6 months on average. Significant use of health care resources was found in the following groups: patients aged 60 years and older, who periodically or regularly measure blood pressure (BP), regularly take antihypertensive therapy (AHT), those who have drug incentives, do not use fixed combinations, with uncontrolled BP, coronary heart disease (СHD), who take 3 or more antihypertensive drugs, who changed or withdrew the recommended AHT. Although achieving target BP is associated with a reduced likelihood of medical emergency calls and outpatient physician’s counseling, there was not difference in the number of hospitalizations between the groups with achieved target BP and the group with uncontrolled HTN. Total direct costs for 6 months composed 9 283,13 rubles per one study participant. Factors associated with a higher total direct costs included age 60 years or older, a high level of self-monitoring of BP, regular intake of AHT, the opportunity of drug incentives, the presence of СHD, uncontrolled HTN, multiple combination antihypertensive therapy (3 drugs and more), no use of fixed combinations, changes or withdrawal of recommended AHT.

Conclusions. Our analysis of resource provision and cost-effectiveness of HTN treatment allowed to identify the groups of patients with inappropriate resource expenses. These data demonstrate the need for targeted interventions in order to reduce the economic burden of HTN.

About the Authors

A. V. Kontsevaya
National Research Centre for Preventive Medicine
Russian Federation

Anna V. Kontsevaya - MD, PhD, Head, Laboratory of Economic Analysis of Epidemiologic Studies and Preventive Technologies, Department of Epidemiology of Chronic Non-infectious Diseases.

10–3, Petroverigskiy lane, Moscow, 101990



T. S. Romanenko
National Research Centre for Preventive Medicine
Russian Federation

Tatyana S. Romanenko - MD, Degree Seeking Applicant, Department of Epidemiology of Chronic Non-infectious Diseases.

10–3, Petroverigskiy lane, Moscow, 101990



M. B. Khudyakov
National Research Centre for Preventive Medicine
Russian Federation

Michail B. Khudyakov - Leading Engineer, Laboratory of Economic Analysis of Epidemiologic Studies and Preventive technologies, Department of Epidemiology of Chronic Noninfectious Diseases.

10–3, Petroverigskiy lane, Moscow, 101990



References

1. Bromfield S, Muntner P. High blood pressure: the leading global burden of disease risk factor and the need for worldwide prevention programs. Curr Hypertens Rep. 2013;15(3):134–136.

2. Balu S, Thomas J. Incremental expenditure of treating hypertension in the United States. Am J Hypertens. 2006;19 (8):810–816.

3. Rosano A, Loha CA, Falvo R, van der Zee J, Ricciardi W, Guasticchi G et al. The relationship between avoidable hospitalization and accessibility to primary care: a systematic review. Eur J Public Health. 2013;23(3):356–60.

4. Walker RL, Chen G, McAlister FA, Campbell NR, Hemmelgarn BR, Dixon E et al. Hospitalization for uncomplicated hypertension: an ambulatory care sensitive condition. Can J Cardiol. 2013;29(11):1462–9.

5. Caminal J, Starfield B, Sánchez E, Casanova C, Morales M. The role of primary care in preventing ambulatory care sensitive conditions. Eur J Public Health. 2004;14(3):246–51.

6. Walker RL, Chen G, McAlister FA, Campbell NR, Hemmelgarn BR, Dixon E et al. Relationship between primary care physician visits and hospital/emergency use for uncomplicated hypertension, an ambulatory care-sensitive condition. Can J Cardiol. 2014;30(12):1640–8.

7. Бойцов С. А., Баланова Ю. А., Шальнова С. А., Деев А. Д., Артамонова Г. В., Гатагонова Т. М. и др. Артериальная гипертония среди лиц 25–64 лет: распространенность, осведомленность, лечение и контроль. По материалам исследования ЭССЕ. Кардиоваскулярная терапия и профилактика. 2014;13 (4):4–14. [Boytsov SA, Balanova YuA, Shalnova SA, Deev AD, Artamonova GV, Gatagonova TM et al. Arterial hypertension among individuals of 25–64 years old: prevalence, awareness, treatment and control. By the data from ECCD. Kardiovaskulyarnaya Terapiya i Profilaktika = Cardiovascular Therapy and Prevention. 2014;13(4):4–14. In Russian].

8. Леонова М. В., Белоусов Ю. Б., Штейнберг Л. Л., Алимова Э. Э., Смирнова Е. П., Белоусов Д. Ю. Результаты фармакоэпидемиологического исследования артериальной гипертонии ПИФАГОР IV (опрос пациентов с артериальной гипертонией). Системные гипертензии. 2015;12(3):11–18. [Leonova MV, Belousov YuB, Shtejnberg LL, Alimova EE, Smirnova EP, Belousov DYu et al. The results of the pharmacoepidemiological study PIFAGOR IV concerning arterial hypertension (AH patients survey). Sistemnye Gipertenzii = Systemic Hypertension. 2015;12 (3):11–18. In Russian].

9. Gibson OR, Segal L, McDermott RA. A systematic review of evidence on the association between hospitalisation for chronic disease related ambulatory care sensitive conditions and primary health care resourcing. BMC Health Serv Res. 2013;13:336.

10. Концевая А. В., Романенко Т. С., Выгодин В. А., Фитилев С. Б. Фармакоэпидемиология и эффективность антигипертензивной терапии в реальной практике специализированного кардиологического учреждения. Рациональная фармакотерапия в кардиологии. 2015;11(1):8–17. [Kontsevaya AV, Romanenko TS, Vygodin VA, Fitilev SB. Pharmacoepidemiology and the efficacy of antihypertensive treatment in real-life practice of the cardiology referral clinic. Ratsional’naja Farmakoterapija v Kardiologii = Rational Pharmacotherapy in Cardiology. 2015;11 (1):8–17. In Russian].

11. Sturm R. The effects of obesity, smoking, and drinking on medical problems and costs. Health Aff (Millwood). 2002;21 (2):245–253.

12. . Бойцов С. А. , Лукьянов М. М . , Якушин С. С . Амбулаторно-поликлинический регистр РЕКВАЗА: данные проспективного наблюдения, оценка риска и исходы у больных с кардиоваскулярными заболеваниями. Кардиоваскулярная терапия и профилактика. 2015;14(1):53–62. [Boytsov SA, Lukyanov MM, Yakushin SS. The outpatient based registry RECVASA: prospective follow-up data, risk evluation and outcomes in cardiovascular patients. Kardiovaskulyarnaya Terapiya i Profilaktika = Cardiovascular Therapy and Prevention. 2015;14(1):53–62. In Russian].

13. Концевая А. В., Романенко Т. С., Выгодин В. А., Фитилев С. Б. Анализ регулярности приема антигипертензивной терапии, как компонента приверженности к лечению, у амбулаторных пациентов специализированного кардиологического учреждения. Рациональная фармакотерапия в кардиологии. 2015;11(3):238–246. [Kontsevaya AV, Romanenko TS, Vygodin VA, Fitilev SB. Evaluation of the regularity of antihypertensive drugs usage as a component of treatment adherence in outpatients of a specialized cardiology center. Ratsional’naja Farmakoterapija v Kardiologii = Rational Pharmacotherapy in Cardiology. 2015;11 (3):238–246. In Russian].

14. Концевая А. В., Романенко Т. С., Выгодин В. А., Фитилев С. Б. Изменение схемы лечения артериальной гипертонии амбулаторных пациентов специализированного кардиологического учреждения и факторы, ассоциированные со сменой антигипертензивной терапии. Российский кардиологический журнал. 2015;4(120):100–106. [Kontsevaya AV, Romanenko TS, Vygodin VA, Fitilev SB. Change of hypertension treatment scheme in outpatient care at specialized cardiologic institution, and factors associated with the change of antihypertension therapy. Russian Journal of Cardiology. 2015;4(120):100–106. In Russian].

15. Billups SJ, Moore LR, Olson KL, Magid DJ. Costeffectiveness evaluation of a home blood pressure monitoring program. Am J Manag Care. 2014;20(9): e380–387.

16. Голиков А. П., Лукьянов М. М., Полумисков В. Ю., Голиков П. П., Давыдов Б. В., Руднев Д. В. Новые возможности лечения и профилактики гипертонических кризов у больных с сочетанием гипертонической болезни и ишемической болезни сердца. Кардиоваскулярная терапия и профилактика. 2005;4 (3–1):10–16. [Golikov AP, Lukyanov MM, Polumiskov VYu, Golikov PP, Davydov BV, Rudnev DV et al. Hypertensive crises in patients with essential arterial hypertension and coronary heart disease: new perspectives in treatment and prevention. Kardiovaskulyarnaya Terapiya i Profilaktika = Cardiovascular Therapy and Prevention. 2005;4(3–1):10–16. In Russian].

17. Monane M, Bohn RL, Gurwitz JH, Glynn RJ, Levin R, Avorn J. The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly. Am J Hypertens. 1997;10(7 Pt 1):697–704.

18. Каракулова Е. В., Клокова М. В., Белоусов М. В., Хабарова И. О., Загромова Т. А. Исследование взаимосвязи комплекса медико-социальных факторов и приверженности фармакотерапии больных хроническими заболеваниями [Электронный ресурс]. Современные проблемы науки и образования: электронный научный журнал. 2013;4. URL: www.science-education.ru/110–9784 [дата обращения: 01.06.2015]. [Karakulova EV, Klokova MV, Belousov MV, Khabarova IO, Zagromova TA et al. Research of the relationship between complex of medical and social factors and adherence to pharmacotherapy patients with chronic diseases [Electronic resource]. Sovremennyie Problemyi Nauki i Obrazovaniya = Modern Problems of Science and Education. 2013;4. Available from: www.science-education.ru/110–9784 [cited 2015 Jun 01]. In Russian].

19. Wu PH, Yang CY, Yao ZL, Lin WZ, Wu LW, Chang CC. Relationship of blood pressure control and hospitalization risk to medication adherence among patients with hypertension in Taiwan. Am J Hypertens. 2010;23(2):155–160.

20. Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care. 2005;43(6):521–530.

21. Campbell NR, Brant R, Johansen H, Walker RL, Wielgosz A, Onysko J et al. Increases in antihypertensive prescriptions and reductions in cardiovascular events in Canada. Hypertension. 2009;53(2):128–134.

22. Tung YC, Lin YS, Wu LS, Chang CJ, Chu PH. Clinical outcomes and healthcare costs in hypertensive patients treated with a fixed-dose combination of amlodipine/valsartan. J Clin Hypertens (Greenwich). 2015;17(1):51–58.

23. Yang W, Chang J, Kahler KH, Fellers T, Orloff J, Wu EQ et al. Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives. Curr Med Res Opin. 2010;26(9):2065–2076.


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Kontsevaya A.V., Romanenko T.S., Khudyakov M.B. RESOURCE MAINTENANCE TREATMENT OF ARTERIAL HYPERTENSION IN OUTPATIENT CLINICS. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2017;23(1):25-35. (In Russ.) https://doi.org/10.18705/1607-419X-2017-23-1-25-35

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ISSN 1607-419X (Print)
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