HYPERTENSION TREATMENT IN THE YOUNG AGE AND IN THE ELDERLY
https://doi.org/10.18705/1607-419X-2014-20-5-406-414
Abstract
The review assesses the current guidelines of hypertension treatment in different age groups and pathophysiology of hypertension according to age. Specific questions concerning prevention of cognitive decline in the elderly are also discussed as well as target blood pressure levels and side effects of the drugs.
About the Author
A. O. Konradi
Federal Almazov Medical Research Centre, St Petersburg
Russian Federation
Federal Almazov Medical Research Centre, 2 Akkuratov street, St Petersburg, Russia, 197341. Tel.: +7(812)702–68–10. MD, PhD, Professor, Vice-Director on Research of the Federal Almazov Medical Research Centre, Head of the Hypertension Research Department at the Federal Almazov Medical Research Centre
Russian Federation
Federal Almazov Medical Research Centre, 2 Akkuratov street, St Petersburg, Russia, 197341. Tel.: +7(812)702–68–10. MD, PhD, Professor, Vice-Director on Research of the Federal Almazov Medical Research Centre, Head of the Hypertension Research Department at the Federal Almazov Medical Research Centre
References
1. 2013 Guidelines for the management of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the EuropeanSociety of Cardiology (ESC) // J. Hypertens. — 2013. — Vol. 31, № 7. — P. 1281–1357.
2. Ong K.L., Cheung B.M.Y., Man Y.B. et al. Prevalence, awareness, treatment, and control of hypertension among United States adults 1999–2004 // Hypertension. — 2007. — Vol. 31, № 49. — P. 69–75.
3. Franklin S.S., Jacobs M.J., Wong N.D., L’Italien G.J., Lapuerta P. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III // Hypertension. — 2001. — Vol. 37, № 3. — P. 869–874.
4. Lloyd-Jones D.M., Evans J.C., Larson M.G. et al. Differential control of systolic and diastolic blood pressure: factors associated with lack of blood pressure control in the community // Hypertension. — 2000. — Vol. 36, № 4. — P. 594–599.
5. Kannel W.B., Dannenberg A.L., Abbott R.D. Unrecognized myocardial infarction and hypertension: the Framingham Study // Am. Heart J. — 1985. — Vol. 109, № 3, Pt. 1. — P. 581–585.
6. Pannier B., Brunel P., Aroussey W.E., Lacolley P., Safar M.E. Pulse pressure and echocardiographic findings in essential hypertension // J. Hypertens. — 1989. — Vol. 7, № 2. — P. 127–132.
7. Gardin J.M., Gottdiener J.S., Wong N.D. et al. Left ventricular mass in the elderly. The Cardiovascular Health Study // Hypertension. — 1997. — Vol. 29, № 5. — P. 1095–1103.
8. Rutan G.H., McDonald R.H., Kuller L.H. A historical perspective of systolic vs diastolic blood pressure from an epidemiological and clinical trial viewpoint // J. Clin. Epidemiol. — 1989. — Vol. 42, № 7. — P. 663–673.
9. Kannel W.B., Wilson P.W.F., Silbershatz H. et al. Epidemiology of risk factor clustering in elevated blood pressure // Gotto A.M., Lenfant C., Paoletti R. (eds). Multiple Risk Factors in Cardiovascular Disease. — The Netherlands: Klewer Academic Publishers and Fondazione Giovanni Lorenzini, 1998. — P. 325–333.
10. Reaven G.M. Insulin resistance, hyperinsulinemia, and hypertriglyceridemia in the etiology clinical course of hypertension // Am. J. Med. — 1991. — Vol. 90, № 2А. — P. 7S–12S.
11. Van Bortel L.M., Struijker-Boudier H.A., Safar M.E. Pulse pressure, arterial stiffness, and drug treatment of hypertension // Hypertension. — 2001. — Vol. 38, № 4. — P. 914.
12. Franklin S. Hypertension in older people: part 1 // J. Clin. Hypertens. — 2006. — Vol. 8, № 6. — P. 444–449.
13. Izzo J. Stagnation and the critical need for hypertension subtyping // Clin. Hypertens. — 2008. — March. — Vol. 10, № 3. — P. 174–175.
14. Mancia G., Grassi G. Treating very elderly hypertensive patients is rewarding: the HYVET results // Curr. Hypertens. Rep. — 2008. — Vol. 10, № 4. — P. 301–302.
15. Mahvan T.D.1, Mlodinow S.G. JNC 8: What's covered, what's not, and what else to consider // J. Fam. Pract. — 2014. — Vol. 63, № 10. — P. 574–584.
16. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP) // J. Am. Med. Assoc. — 1991. — Vol. 265, № 24. — P. 3255–3264.
17. Williams B.R., Kim J. Cardiovascular drug therapy in the elderly: theoretical and practical considerations // Drugs Aging. — 2003. — Vol. 20, № 6. — P. 445–463.
18. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) // J. Am. Med. Assoc. — 2002. — Vol. 288, № 23. — P. 2981–2997.
19. Messerli F.H., Grossman E., Goldbourt U. Are beta-block-ers efficacious as first-line therapy for hypertension in the elderly? A systematic review // J. Am. Med. Assoc. — 1998. — Vol. 279, № 23. — P. 1903–1907.
20. Tu K., Campbell N.R.C, Chen Z., McAlister F.A. Use of beta-blockers for uncomplicated hypertension in the elderly: a cause for concern // J. Hum. Hypertens. — 2007. — Vol. 21, № 4. — P. 271–275.
21. Rodgers J.E., Patterson J.H. Angiotensin II-receptor blockers: clinical relevance and therapeutic role // Am. J. Health Syst. Pharm. — 2001. — Vol. 58, № 8. — P. 671–683.
22. Schrander J., Luders S., Kulschewski A. et al. Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention (MOSES study) // Stroke. — 2005. — Vol. 36, № 6. — P. 1218–1226.
23. Petrella R.J.1, Shlyakhto E.V., Konradi A.O. et al. OSCAR Publication Group. Blood pressure responses to hypertension treatment and trends in cognitive function in patients with initially difficult-to-treat hypertension: a retrospective subgroup analysis of the Observational Study on Cognitive Function and SBP Reduction (OSCAR) study // J. Clin. Hypertens. (Greenwich). — 2012. — Vol. 14, № 2. — P. 78–84.
24. Papademetriou V., Farsang C., Elmfeldt D. et al. Study on Cognition and Prognosis in the Elderly study group. Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE) // J. Am. Coll. Cardiol. — 2004. — Vol. 44, № 6. — P. 1175–1180.
25. Akamine D., Filho M.K., Peres C.M. Drug-nutrient interactions in elderly people // Curr. Opin. Clin. Nutr. Metab. Care. — 2007. — Vol. 10, № 3. — P. 304–310.
26. Oliveria S.A., Lapuerta P., McCarthy B.D. et al. Physician-related barriers to the effective management of uncontrolled hypertension // Arch. Intern. Med. — 2002. — Vol. 162, № 4. — P. 413–420.
27. Hajjar I., Miller K., Hirth V. Age-related bias in the management of hypertension: a national survey of physicians’ opinions on hypertension in elderly adults // J. Gerontol. — 2002. — Vol. 57A, № 8. — P. M487–M491.
28. Sica D.A. Rationale for fixed-dose combinations in the treatment of hypertension: the cycle repeats // Drugs. — 2002. — Vol. 62, № 3. — P. 443–462.
29. Franklin S.S. Systolic blood pressure: it's time to take control // Am. J. Hypertens. — 2004. — December. — Vol. 17, № 12, Pt. 2. — P. 49S–54S.
30. Ekpo E.B., Shah I.U., Fernando M.U., White A.D. Isolated systolic hypertension in the elderly: survey of practitioners’ attitude and management // Gerontology. — 1993. — Vol. 39, № 4. — P. 207–214.
Review
For citations:
Konradi A.O. HYPERTENSION TREATMENT IN THE YOUNG AGE AND IN THE ELDERLY. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2014;20(5):406-414. https://doi.org/10.18705/1607-419X-2014-20-5-406-414
Views:
1079
Email this article 