Hormonal, immunological and psychological markers of emotional stress in hypertensive patients
https://doi.org/10.18705/1607-419X-2018-24-2-151-161
Abstract
Objective. The objective was to study the relationship of mental and emotional stress, metabolic characteristics, structural and functional parameters of the heart and blood vessels in men with hypertension (HTN). Design and methods. We included 120 men, among them 70 subjects had HTN I–II stage (mean age 21,4 ± 2,3 years, mean ± SD) and 50 healthy individuals (mean age 21,5 ± 1,4 years, mean ± SD). All patient study of hormonal, lipid, fasting venous blood immunological parameters, ultrasound of the heart and blood vessels, blood pressure measurement according to standard procedure, 24‑hour blood pressure monitoring, and psychological questionnaires were performed. Results. Young men with HTN showed higher levels of cortisol, interleukin‑6, low density lipoprotein cholesterol, atherogenic index. Psychological features of hypertensive subjects were characterized by a predominance of personal anxiety, certain coping-strategies (distancing, self-control, acceptance of responsibility). The identified associations of psychological, structural and functional parameters of the heart can be useful for planning programs for early prevention of cardiovascular remodeling in HTN patients. Conclusions. Understanding the relationship of mental and somatic factors, we can find out the mechanisms of pathology development and to implement new methods of preventive medicine at the individual and population level, strategy of interaction between psychiatrists, medical psychologists and physicians.
About the Author
O. Yu. Bastrikov
South Ural State Medical University
Russian Federation
MD, PhD, Associate Professor, Department of Internal Diseases
Russian Federation
MD, PhD, Associate Professor, Department of Internal Diseases
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Review
For citations:
Bastrikov O.Yu. Hormonal, immunological and psychological markers of emotional stress in hypertensive patients. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2018;24(2):151-161. (In Russ.) https://doi.org/10.18705/1607-419X-2018-24-2-151-161
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