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Does hypertension during pregnancy contribute to female metabolic syndrome?

https://doi.org/10.18705/1607-419X-2006-12-2-117-120

Abstract

The aim of the study was to assess metabolic abnormalities in women with different patterns of hypertension during pregnancy in a prospective long-term observational study. 38 females were followed for 10 years after pregnancy. 16 females with normal pregnancy served as a control group. It is shown than hypertension during pregnancy predispose to blood pressure stabilization, target organ damage as well as metabolic disturbances and can predispose to metabolic syndrome manifestation. Maternal weight before pregnancy, and weight increase during pregnancy are predictors of future metabolic syndrome. It was shown also that enalapril 5-20 mg per day can significantly reduce blood pressure and improve metabolic glucose and lipid parameters in such women.

About the Authors

O. N. Tkacheva
МГМСУ
Russian Federation


N. F. Razgulaeva
МГМСУ
Russian Federation


K. Y. Guseva
МГМСУ
Russian Federation


N. S. Samsonenko
МГМСУ
Russian Federation


I. E. Mishina
ГОУ ВПО ИвГМА Росздрава
Russian Federation


A. V. Barabashkina
Владимирская областная клиническая больница
Russian Federation


L. P. Maksimenko
МУЗ «Городская клиническая больница №3 г. Иванова»
Russian Federation


I. P. Mokeeva
МУЗ «Городская клиническая больница №3 г. Иванова»
Russian Federation


References

1. Чазова И.E., Мычка В.Б. Метаболический синдром. Consilium Medicum 2004; 4(1).

2. Despres J.P., Lamarche В., Mauriege P. et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Eng J Med 1996; 334 (15): 952-57.

3. Richard P.D., Trevor J.O. Hyperinsulinemia and resistance: associations with cardiovasculars and disease. Cardiovasc rise factors 1993; 1: 12-18.

4. Davis B.R., Cutler J.D., Gordon D.J. et al. Rationale and design for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Am J Hyperten. 1996; 9:342-60.

5. Gluckman P.D., Hanson M.A. The developmental origins of the metabolic syndrome. Trends Endocrinol. Metab. 2004; 15(4) :183-7.

6. Williams D. Pregnancy: a stress test for life. Cur Opin Obstet Gynecol 2003; 15(6): 465-71.

7. Ong K.K., Dunger D.B. Birth weight, infant growth and insulin resistance. Eur Endocrino. 2004; 151 (Suppl 3):U131-9.

8. Pouta A., Hartikainen A.L., Sovio U. et al. Manifestations of metabolic syndrome after hypertensive pregnancy. Hypertension. 2004; 43(4): 825-31.

9. Rodie V.A., Freeman D.J., Sattar N., Greer L.A. Pre-eclampsia and cardiovascular disease: metabolic syndrome of pregnancy? Atherosclerosis. 2004; 175(2): 189-202.

10. Barbieri R.L. 1999 Endocrine disorders in pregnancy. In: Yen SSC,Jaffe RB, Barbieri RL, eds. Reproductive endocrinology. Philadelphia: Saunders; 785-811

11. Belo L., Caslake M., Gaffney D. et al. Changes in LDL size and HDL concentration in normal and preeclamptic pregnancies. Atherosclerosis 2002;162:425-432

12. Ogura K., Miyatake T., Fukui O. et al. Low-density lipoprotein particle diameter in normal and preeclampsia, J Atheroscler Thromb 20029:42-47

13. Sattar N., Greer I.A., Rumley A. et al. A longitudinal study of the relationships between between haemostatic, lipid, and oestradiol changes during normal human pregnancy. Thromb Haemost 1999 81:71-75

14. Caruso A., Ferrazzani S., De Carolis S. et al. Gestational hypertension but not pre-eclampsia is associated with insulin resistance syndrome characteristics. Hum Reprod 1999;14:219-223

15. Kaaje R., Laivuori H., Laasko M. et al. Evidence of a state of increased insulin resistance in preeclampsia. Metabolism 1999; 48: 892-896

16. Sermer M., Naylor C.D., Gare D.J. et al. Impact of increasing carbohydrate intolerance on maternal-fetal outcomes in 3637 women without gestational diabetes: the Toronto Trihospital Gestational Project. Am J Obstet Gynecol 1995;173:146-156

17. Joffe G.M., Esterlitz J.R., Levine R.J. et al. The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women: Calcium for Preeclampsia Prevention (CPEP) study group. Am J Obstet Gynecol 1998; 179:1032-1037

18. Solomon C.G., Graves S.W., Greene M.F., Seely E.W. Glucose intolerance as a predictor of hypertension in pregnancy. Hypertension 19994; 23:717-721

19. Solomon C.G., Carroll J.S., Okumura K. et al. Higher cholesterol and insulin levels are associated with increased risk for pregnancy-induced hypertension. Am J Hypertens 1999;12:276-282

20. Sowers J.R., Sokol R.J., Standley P.R. et al. Insulin resistance and increased body mass index in women developing hypertension in pregnancy. Nutr Metab Cardiovasc Dis 1996; 6:141-146

21. Innés K.E., Wimsatt J.H., McDuffie R. 2001 Relative glucose tolerance and subsequent development of hypertension in pregnancy. Obstet Gynecol 97:905-910

22. Thadhani R., Stampfer M.J., Hunter D.J. et al. High body mass index and hypercholesterolemia: risk of hypertensive disorders of pregnancy. Obstet Gynecol 1999; 94:543-550

23. Sattar N., Clark P., Holmes A. et al. Antenatal waist circumference and hypertension risk. Obstet Gynecol 2001; 97:268-271

24. Saftlas A., Wang W., Risch H. et al. Prepregnancy body mass index and gestational weight gain as risk factors for preeclampsia and transient hypertension. Ann Epidemiol 2000,10:475

25. Marcoux S., Brisson J., Fabia J. The effect of leisure time physical activity on the risk of pre-eclampsia and gestational hypertension. J Epidemiol Community Health 1989;43:147-152


Review

For citations:


Tkacheva O.N., Razgulaeva N.F., Guseva K.Y., Samsonenko N.S., Mishina I.E., Barabashkina A.V., Maksimenko L.P., Mokeeva I.P. Does hypertension during pregnancy contribute to female metabolic syndrome? "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2006;12(2):117-120. (In Russ.) https://doi.org/10.18705/1607-419X-2006-12-2-117-120

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ISSN 1607-419X (Print)
ISSN 2411-8524 (Online)