Fixed low-dose combinations of perindopril and indapamide in inadequately controlled hypertensive patients

Abstract

The study addresses efficacy of fixed combinations of perindopril and indapamide (Noliprel and Noliprel-forte) in inadequately controlled hypertensive patients previously treated by free administrated combination therapy. 122 patients were followed-up for 3 months. Patients with mild hypertension were treated by Noliprel and patients with moderate-to-severe hypertension received Noliprel-forte. Efficacy, tolerability and quality of life were assessed initially and after 12 weeks of treatment. Is was shown that fixed combinations of perindopril and indapamide can help to effectively reach target blood pressure and can be successfully used as a "step" approach of therapy of different stages of hypertension.