Morhological characteristics of exiperimental miocardial infarction after granulocyte growth factor injection
https://doi.org/10.18705/1607-419X-2007-13-3-208-211
Abstract
G-CSF effects on experimental myocardial infarction in rats have been studied. Morphometrical evaluation was performed of the infracted zone as well as of the density of capillary and undifferentiated vessels in the surrounding granulation (issue. By day 7 G-CSF had no influence on the size of the infracted area, but I he vessel density eras substantially increased following administration of G-CSF. Existing data on G CSF effects on angiogenesis art- controversial. The results obtained favor stimulatory effect оf G-CSF on angiogenesis in healing of the myocardial in fare I ion.
About the Authors
Т. Н. Nutfullina
Санкт-Петербургский государственный медицинский университет имени академика И.П.Павлова
Russian Federation
Russian Federation
A. N. Krutikov
Санкт-Петербургский государственный медицинский университет имени академика И.П.Павлова
Russian Federation
Russian Federation
H. K. Amineva
Санкт-Петербургский государственный медицинский университет имени академика И.П.Павлова
Russian Federation
Russian Federation
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Review
For citations:
Nutfullina Т.Н., Krutikov A.N., Amineva H.K. Morhological characteristics of exiperimental miocardial infarction after granulocyte growth factor injection. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2007;13(3):208-211. (In Russ.) https://doi.org/10.18705/1607-419X-2007-13-3-208-211
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