BLOOD VELOCITY IN FUNCTION OF ARTERIOLES IN HYPERTENSIVE PATIENTS
https://doi.org/10.18705/1607-419X-2013-19-1-38-43
Abstract
Objective. To study blood velocity in arterioles in hypertensive patients by doppler.
Design and methods. We assessed blood velocity in 90 patients with essential arterial hypertension (AH) and in 83 patients with type 2 diabetes mellitus (DM2) with AH («Minimax-Doppler-K»), and in 102 control subjects: during systole (Vs, cm/s), diastole (Vd, cm/s) and during the mean blood flow cycle (Vm, cm/s). Then spontaneous changes of blood velocity were recorded during 1 minute. In patients with DM2 association between blood velocity and disease duration was studied. In 43 hypertensive patients Vs and Vd were defined after treatment.
Results. Hypertensive patients had the highest blood velocity, lower values were defined in healthy people, and hypertensive subjects with DM2demonstrated the lowest blood velocity. Fluctuations in blood velocity during systole were the highest in healthy people, less in hypertensives and the smallest in subjects with DM2 and AH. Variations of blood velocity during diastole were the highest in AH patients, less in patients with DM2 with AH and the least in healthy subjects. Blood velocity in arterioles is lower in patients with the longer duration of DM2. In treated hypertensive patients blood velocity in arterioles reduces. Conclusion. By assessment of blood flow velocity in arterioles we can evaluate the functional state of these vessels in hypertensive patients.
About the Authors
O. B. PoselyuginaRussian Federation
Corresponding author: Tver State Medical Academy, 105 St Petersburg way, Tver, Russia, 170000. Phone: 8 (4822) 76–52–85. E-mail: Poselubina@mail.ru (Olga B. Poselyugina, MD, PhD, an Associate Professor at the Department of Internal and Professional Diseases at Tver State Medical Academy).
V. S. Volkov
Russian Federation
E. V. Rudenko
Russian Federation
N. Al Ghalban
Russian Federation
References
1. Мостовой С.Е., Дынник О.Б., Трихлеб В.И. и др. Оценка состояния микроциркуляторного русла кожи при диффузных заболеваниях печени методом лазерной допплеровской флоуметрии // Регионарное кровообращение и микроциркуляция. — 2007. — № 1. — С. 111–112. / Mostovoy S.E., Dynnik O.B., Trihleb V.I. et al. Evaluation of microcirculation of the skin with diffuse liver disease by laser Doppler fl owmetry // Regional Blood Circulation and Microcirculation [Regionarnoye Krovoobrascheniye i Mikrotsirkulyatsiya]. — 2007. — № 1. — P. 111–112 [Russian].
2. Бранько В.В., Вахлеев В.Д., Богданова Э.А. Применение ЛДФ в кардиологии // Рос. мед. журн. — 1998. — № 3. — С. 34–38. / Branko V., Vahleev V.D., Bogdanova E.A. LDF application in cardiology // Russian Medical Journal [Rossiyskiy Meditsinskiy Zhurnal]. — 1998. — № 3. — P. 34–38 [Russian].
3. Гогин Е.Е. Микроциркуляция при ишемической болезни сердца и артериальной гипертонии // Терапевт. aрх. — 2006. — № 4. — С. 5-6. / Gogin E.E. Microcirculation in coronary heart disease and hypertension // Therapeutic Archive [Terapevticheskiy Arkhiv]. — 2006. — № 4. — P. 5–6 [Russian].
4. Руденко Е.В. Функциональные особенности микроциркуляции у больных сахарным диабетом 2 типа с сопутствующей артериальной гипертонией // Сахарный диабет. — 2008. — Т. 38, № 1. — С. 28–29. / Rudenko E.V. Functional characteristics of the microcirculation in patients with type 2 diabetes with arterial hypertension // Diabetes [Sakharniy Diabet]. — 2008. — Vol. 38, № 1. — P. 28–29 [Russian].
5. Дедов И.И. Сахарный диабет в Российской Федерации: проблемы и пути решения // Сахарный диабет. — 1998. — № 1. — С. 7–18. / Dedov I.I. Diabetes mellitus in the Russian Federation: problems and solutions // Diabetes [Sakharniy Diabet]. — 1998. — Vol. 28, № 1. — P. 7–18 [Russian].
6. Mazzucco J., Bertani T., Fortunato M. et al. Different patterns of renal damage in type 2 diabetes mellitus: a multicentre study on 393 biopsies // Am. J. Kidney Dis. — 2002. — Vol. 39, № 4. — Р. 713–720.
7. Iacobellis J., Cipriani R., Jabriele A. et al. High circulating vascular endothelial growth factor (VEJF) is related to better systolic function in diabetic hypertensive patients // Cytokine. — 2004. —Vol. 27, № 1. — Р. 25–30.
8. Аметов А.С. Cахарный диабет 2 типа. Проблемы и решения. — М.: ГЭОТАР-Медиа. — 2012. — 702 c. / Ametov A.S. Type 2 diabetes mellitus. Problems and solutions. — Moscow: GEOTAR-Media. — 2012. — 702 p. [Russian].
9. Ward R., Sparrow D., Landsberg L. et al. The infl uence of obesity, insulin and sympathetic nervous system activity on blood pressure // Clin. Res. — 1993. — Vol. 41. — P. 168–174.
10. Glans R.O., Bilo H.J., Donker A.J. The renal response to exogenous insulin in non-insulin-dependent diabetes mellitus in relation to blood pressure and cardiovascular hormonal status // Dial. Transplant. — 1996. — Vol. 11, № 5. — P. 794–802.
11. Волков В.С., Поселюгина О.Б., Нилова С.А., Роккина С.А. Уровень артериального давления и потребление поваренной соли у больных артериальной гипертонией // Артериальная гипертензия. — 2011. — Vol. 17, № 1. — C. 69–73. /
12. Volkov V., Poselugina O.B., Nilova S.A., Rokkina S.A. The level of blood pressure and consumption of salt in patients with arterial hypertension // Arterial Hypertension [Arterialnaya Gipertenziya]. —2011. — Vol. 17, № 1. — P. 69–73 [Russian].
13. Дедов И.И., Шестакова М.В. Сахарный диабет и артериальная гипертония. МИА. — 2006. — 344 с. / Dedov I.I., Shestakov M.V. Diabetes and hypertension. MIA. — 2006. — 344 p. [Russian].
Review
For citations:
Poselyugina O.B., Volkov V.S., Rudenko E.V., Al Ghalban N. BLOOD VELOCITY IN FUNCTION OF ARTERIOLES IN HYPERTENSIVE PATIENTS. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2013;19(1):38-43. (In Russ.) https://doi.org/10.18705/1607-419X-2013-19-1-38-43