Adenos ine diphosphate-induced platelet aggregation in patients with coronary artery disease and concomitant anxiety and depression
https://doi.org/10.18705/1607-419X-2009-15-2-181-184
Abstract
We studied the changes in adenosine diphosphate (ADP)-induced platelet aggregation in patients with coronary artery disease (CAD) and concomitant anxiety and depression. We found a significant reduction of platelet aggregation response (time of aggregation at ADP concentration 1,25 and 2,5 µM, maximum percentages of aggregation at ADP concentrarion 1,25 µM) in plasma of patients with CAD and concomitant anxiety and depression as compared with patients with CAD without anxiety and depression. Our results do not support hypothesis of an increased thrombosis in patients with CAD and anxiety and depression.
About the Authors
S. Kozlova
Almazov federal heart, blood and endocrinology centre
Russian Federation
Russian Federation
A. V. Golubev
Pavlov State Medical University
Russian Federation
Russian Federation
U. S. Krylova
Almazov federal heart, blood and endocrinology centre
Russian Federation
Russian Federation
I. Y. Efimova
Pavlov State Medical University
Russian Federation
Russian Federation
E. V. Shlyakhto
Almazov federal heart, blood and endocrinology centre
Russian Federation
Russian Federation
N. G. Neznanov
Pavlov State Medical University
Russian Federation
Russian Federation
M. I. Kadinskaya
Pavlov State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Kozlova S., Golubev A.V., Krylova U.S., Efimova I.Y., Shlyakhto E.V., Neznanov N.G., Kadinskaya M.I. Adenos ine diphosphate-induced platelet aggregation in patients with coronary artery disease and concomitant anxiety and depression. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2009;15(2):181-184. (In Russ.) https://doi.org/10.18705/1607-419X-2009-15-2-181-184
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