Association of arterial wall stiffness with cardiovascular risk factors
https://doi.org/10.18705/1607-419X-2009-15-3-290-295
Abstract
Objective. To assess relation between central blood pressure and arterial stiffness with cardiovascular risk factors. Design and methods. 116 subjects considering themselves healthy were examined. 63 showed blood pressure elevation. Anthropometry was performed and fasting blood specimens were obtained from all patients. Plasma glucose and lipids levels were measured. Pulse wave velocity (PWV) and augmentation index (AI) were measured by Sphygmocor Px device (Australia). Results. Parameters of arterial stiffness were strongly associated with hypertension, increased waist circumference, age, cholesterol level, and metaboloc syndrome. Females had higher AI as compared to males. Conclusion. Central blood pressure and arterial stiffness are determined not only by age and peripheral blood pressure but by cholesterol level and anthropometric parameters as well.
About the Authors
V. V. Ivanenko
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
O. P. Rotar
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
A. Konradi
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
References
1. Guidelines for the Management of Arterial Hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // J. Hypertens. - 2007. - Vol. 25. - P. 1105−1187.
2.
3. Heanson T., Staessen J., Pedersen T. et al. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in general population // Circulation. - 2006. - Vol. 113. - Vol. 664-670.
4.
5. Asmar R. Arterial stiffness and pulse wave velocity - Clinical applications. Paris: Elsevier; 1999. P. 9-43.
6.
7. Lakatta E.G. Cardiovascular ageing in health sets the stage for cardiovascular disease // Heart Lung Circ. - 2002. - Vol. 11. - P. 76-91.
8.
9. Laurent S., Cocroft J. Central aortic blood pressure. Elsevier. 2008, P. 65.
10.
11. Blacher J., Guerin A., Marchias S.J. et al. Impact of aortic stiffness on survival in end-stage renal disease // Circulation. - 1999. - Vol. 99. - P. 2434-2439.
12.
13. Boutouyrie P., Tropeano A.I., Asmar R. et al. Aortic stiffness as an independent predictor of primary coronary events in hypertensive patients: a longitudinal study // Hypertension. - 2002. - Vol. 39. - P. 10-15.
14.
15. Asmar J., Ruidavets J.B., Charmontin B. et al. Arterial stiffness and cardiovascular risk factors in a population-based study // J. Hypertens. - 2001. - Vol. 19. - P. 381-387.
16.
17. Laurent S., Boutouyrie P., Asmar R. et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients // Hypertension. - 2001. - Vol. 37. - P. 1236.
18.
19. Laurent S., Katsahian S., Fassot C. et al. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension // Stroke. - 2003. - Vol. 34, № 5. - P. 1203-1206.
20.
21. Willum-Hansen T ., Staessen J.A ., Torp-Pedersen C. et al. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population // Circulation. - 2006. - Vol. 113, № 5. - P. 664-670.
22.
23. Laurent S., Boutouyrie P. Impact of essential hypertension on the arteries // Rev. Prat. - 1999. - Vol. 49, № 5. - P. 495-502.
24.
25. Grundy S.M., Cleeman J.I., Daniels S.R. et al. Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement // Circulation. - 2005. - Vol. 112. - P. 2735-2752.
26.
27. Safar M.E. Pulse pressure, arterial stiffness and wave reflections (augmentation index) as cardiovascular risk factors in hypertension // Ther. Adv. Cardiovasc. Dis. - 2008. - Vol. 2, № 1. - P. 13-24.
28.
29. Shimizu M., Kario K. Role of the augmentation index in hypertension // Ther. Adv. Cardiovasc. Dis. - 2008. - Vol. 2, № 1. - Vol. 25--35.
30.
31. Otsuka T., Kawada T., Ibuki C. et al. Obesity as an independent influential factor for reduced radial arterial wave reflection in a middle-aged Japanese male population // Hypertens. Res. - 2009. - Vol. 32, № 5. - P. 387-391.
32.
33. Tomiyama H., Yamazaki M., Sagawa Y. Synergistic effect of smoking and blood pressure on augmentation index in men, but not in women // Hypertens. Res. - 2009. - Vol. 32, № 2. - P. 122-126.
34.
35. van Trijp M.J., Beulens J.W., Bos W.J. Alcohol consumption and augmentation index in healthy young men: the ARYA study // Am. J. Hypertens. - 2005. - Vol. 18, № 6. - P. 792-796.
36.
37. Vyssoulis G.P., Pietri P.G., Karpanou E.A. Differential impact of metabolic syndrome on arterial stiffness and wave reflections: Focus on distinct definitions // Int. J. Cardiol. - 2008 in press.
38.
39. Kovaite M., Petrulioniene Z., Ryliskyte L. Systemic assessment of arterial wall structure and function in metabolic syndrome // Proc. West Pharmacol. Soc. - 2007. - Vol. 50. - P. 123-130.
40.
41. Aznaouridis K., Vlachopoulos C., Dima I. Triglyceride level is associated with wave reflections and arterial stiffness in apparently healthy middle-aged men // Heart. - 2007. - Vol. 93, № 5. - P. 613-614.
42.
43. Saba P.S., Roman M.J., Longhini C. et al. Carotid intimal-medial thickness and stiffness are not affected by hypercholesterolemia in uncomplicated essential hypertension // Arterioscler. Thromb. Vasc. Biol. - 1999. - Vol. 19, № 11. - P. 2788-2794.
44.
45. Noon J.P., Trischuk T.C., Gaucher S.A. et al. The effect of age and gender on arterial stiffness in healthy Caucasian Canadians // J. Clin. Nurs. - 2008. - Vol. 17, № 17. - P. 2311-2317.
46.
Review
For citations:
Ivanenko V.V., Rotar O.P., Konradi A. Association of arterial wall stiffness with cardiovascular risk factors. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2009;15(3):290-295. (In Russ.) https://doi.org/10.18705/1607-419X-2009-15-3-290-295
Views:
1078
Email this article 