Elastic artery wall in hyper-tensive patients with different patterns of left ventricle remodeling
https://doi.org/10.18705/1607-419X-2009-15-3-296-299
Abstract
Objective: to estimate common carotid arteries wall state in hypertensive patients with different types of left ventricle (LV) remodeling.
Materials and methods: 102 patients 30-65 years old with essential arterial hypertension were examined. The average arterial hypertension length was 7,1 ± 1,2 years. Ultrasound examination of heart and common carotid arteries was performed. The subgroups were formed depending on the type of geometric left ventricle remodeling recommended by A. Canau et al. (1992). Structural changes of common carotid arteries walls and central hemodynamics parameters were estimated. Results: patients with concentric left ventricle hypertrophy demonstrated high arterial stiffness index (6,81 ± 1,1 units) and thickness of arterial intima-media complex (1,0 ± 0,18 mm), significantly differing from subgroups with normal type of LV and eccentric hypertrophy of LV (EHLV) (p < 0,05). Patients with EHLV have bigger internal diameter of carotid arteries (6,42 ± 0,2 mm) as compared to other subgroups (p < 0,05). Summary: patients with essential arterial hypertension show different structural changes of elastic arteries wall depending on the type of left ventricle remodeling.
Materials and methods: 102 patients 30-65 years old with essential arterial hypertension were examined. The average arterial hypertension length was 7,1 ± 1,2 years. Ultrasound examination of heart and common carotid arteries was performed. The subgroups were formed depending on the type of geometric left ventricle remodeling recommended by A. Canau et al. (1992). Structural changes of common carotid arteries walls and central hemodynamics parameters were estimated. Results: patients with concentric left ventricle hypertrophy demonstrated high arterial stiffness index (6,81 ± 1,1 units) and thickness of arterial intima-media complex (1,0 ± 0,18 mm), significantly differing from subgroups with normal type of LV and eccentric hypertrophy of LV (EHLV) (p < 0,05). Patients with EHLV have bigger internal diameter of carotid arteries (6,42 ± 0,2 mm) as compared to other subgroups (p < 0,05). Summary: patients with essential arterial hypertension show different structural changes of elastic arteries wall depending on the type of left ventricle remodeling.
About the Authors
L. F. Bartosh
Penza University of Advanced Medical Studies
Russian Federation
Russian Federation
L. Melnikova
Penza University of Advanced Medical Studies
Russian Federation
Russian Federation
References
1. Михайлов В.В. Основы патологической физиологии. Руководство для врачей. Москва; 2001. с. 459-82.
2.
3. Морман Д., Хеллер Л. Физиология сердечно-сосудистой системы. С.-Петербург, 2000. 114 с.
4.
5. Ollerenshaw J.D., Heagerty A.M., West P.W. et al. The effects of coarctation hypertension upon vascular inositol phospholipids hydrolysis in Wistar rats // J. Hypertension. - 1988. - Vol. 6. - P. 733-738.
6.
7. Devereux R.B., Reichek N. Echocardiographic determination of left ventricular mass in man // Circulation. - 1977. - Vol. 53. - P. 613-618.
8.
9. Ganau A., Devereux R.B., Roman M.J. et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension // J. Am. Coll. Cardiol. - 1992. - Vol. 19. - P. 1550-1558.
10.
11. Kawasaki T., Sasayama S., Yagi S. et al. Nonivasive measurement of the age related changes in stiffness of major branches of the human arteries // Cardiovasc. Res. - 1987. - Vol. 21. - P. 678-687.
12.
13. Devereux R.B., Casale P.N., Savage D.D. et al. Relation of left ventricular mass and geometry in morbidity and mortality in uncomplicated essential hypertension // Ann. Intern. Med. - 1991. - Vol. 114. - P. 345-352.
14.
15. Бойцов С.С. Изучение патогенеза гипертонической болезни продолжается // Тер. архив. - 2006. - Vol. 9. - C. 5-12.
16.
17. London G.M. Role of arterial wall properties in the pathogenesis of systolic hypertension // Am. J. Hypertens. - 2005. - Vol. 18. - P. 19-22.
18.
19. O´Rourke M.F. Mechanical principles in arterial disease // Hypertension. - 1995. -Vol. 26. - P. 2-9.
20.
21. Лелюк В.Г., Лелюк С.Э. Церебральное кровообращение и артериальное давление. Москва, 2004. 22 c.
22.
23. Верещагин Н.В., Моргунов В.А., Гулевская Т.С. Патология головного мозга при атеросклерозе и артериальной гипертензии. Москва, 1997. 287 c.
24.
25. Каро К., Педли Т., Шротер Р., Сид У. Механика кровообращения. Москва, 1981. 300 c.
26.
27. Korner P., Jennings G., Esler M. The cardiovascular amplifiers in human primary hypertension and their role in a strategy for detecting the underlying causes // Can. J. Physiol. Pharmacol. - 1987. - Vol. 65. - P. 1730-1738.
28.
Review
For citations:
Bartosh L.F., Melnikova L. Elastic artery wall in hyper-tensive patients with different patterns of left ventricle remodeling. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2009;15(3):296-299. (In Russ.) https://doi.org/10.18705/1607-419X-2009-15-3-296-299
Views:
866
Email this article 