A potential role for pro-inflammatory cytokines in progress of anxiety and depression in patients with coronary artery disease
https://doi.org/10.18705/1607-419X-2009-15-4-497-501
Abstract
We studied the levels of IL-1, IL-6 and TNF- in patients with coronary artery disease (CAD) and with concomitant anxiety and depression. We found a significant growth these parametres in patients with CAD and with concomitant anxiety and depression as compared with patients with CAD without anxiety and depressive disorders. The level of IL-6 was significant decreased in patients with isolated anxiety and depression as compared with patients with CAD and anxiety and depression. Our results support cytocines hypothesis of depression in patients with CAD and concomitant anxiety and depression.
About the Authors
S. N. Kozlova
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
St Petersburg
Russian Federation
St Petersburg
A. V. Golubev
Pavlov St Petersburg State Medical University
Russian Federation
St Petersburg
Russian Federation
St Petersburg
U. S. Krilova
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
St Petersburg
Russian Federation
St Petersburg
K. A. Syssoev
Center of Molecular Medicine, Pavlov St Petersburg State Medical University
Russian Federation
St Petersburg
Russian Federation
St Petersburg
E. V. Shlyakhto
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
St Petersburg
Russian Federation
St Petersburg
N. G. Neznanov
Pavlov St Petersburg State Medical University
Russian Federation
St Petersburg
Russian Federation
St Petersburg
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Review
For citations:
Kozlova S.N., Golubev A.V., Krilova U.S., Syssoev K.A., Shlyakhto E.V., Neznanov N.G. A potential role for pro-inflammatory cytokines in progress of anxiety and depression in patients with coronary artery disease. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2009;15(4):497-501. (In Russ.) https://doi.org/10.18705/1607-419X-2009-15-4-497-501
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